Human small‐cell lung‐cancer cells are cytokine‐resistant but NK/LAK‐sensitive

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Genomic sequencing.

1984 • 8,343 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

Human granulocyte colony-stimulating factor: biologic activities and receptor characterization on hematopoietic cells and small cell lung cancer cell lines

1990 • 239 citations

Tumor Necrosis Factors: Gene Structure and Biological Activities

1986 • 215 citations

Selective growth in serum-free hormone-supplemented medium of tumor cells obtained by biopsy from patients with small cell carcinoma of the lung.

1981 • 208 citations

Sensitivity of the Epstein-Barr Virus Transformed Human Lymphoid Cell Lines to Interferon

1975 • 185 citations

The Endocrine Lung in Health and Disease

1985 • 160 citations

Inhibition of Cell Division by Interferons

1981 • 111 citations

Characterization of three small cell lung cancer cell lines established from one patient during longitudinal follow-up.

1988 • 83 citations

Differential expression of platelet‐derived growth factor and transforming growth factor genes in small‐ and non‐small‐cell human lung carcinoma lines

1988 • 78 citations

Interferon gamma and granulocyte/macrophage colony-stimulating factor inhibit growth and induce antigens characteristic of myeloid differentiation in small-cell lung cancer cell lines.

1986 • 78 citations

Peptides and growth factors in small cell lung cancer: production, binding sites, and growth effects

1988 • 74 citations

Characteristics and mechanism of IFN-gamma-induced protection of human tumor cells from lysis by lymphokine-activated killer cells.

1988 • 72 citations

How does interferon inhibit tumor growth?

1985 • 71 citations

Effect of recombinant monokines, lymphokines, and other agents on clonal proliferation of human lung cancer cell lines.

1987 • 63 citations

Expression of endogenous tumor necrosis factor as a protective protein against the cytotoxicity of exogenous tumor necrosis factor.

1990 • 56 citations

Up‐ and down‐regulation of human lymphokine (IL‐2)‐activated killer cell induction by monocytes, depending on their functional state

1988 • 49 citations

Biology of small-cell lung cancer

1992 • 48 citations

Lack of correlation between levels of MHC class I antigen and susceptibility to lysis of small cellular lung carcinoma (SCLC) by natural killer cells

1990 • 46 citations

Lack of correlation between levels of MHC class I antigen and susceptibility to lysis of small cellular lung carcinoma (SCLC) by natural killer cells.

1989 • 40 citations

Antiproliferative and differentiative effect of granulocyte-macrophage colony-stimulating factor on a variant human small cell lung cancer cell line

1990 • 37 citations

A phase I trial of recombinant interleukin-2 combined with recombinant interferon-gamma in patients with cancer.

1990 • 35 citations

Expression of myeloid and major histocompatibility antigens on small cell carcinoma of the lung cell lines analyzed by cytofluorography: modulation by gamma-interferon.

1986 • 33 citations

How does interferon inhibit tumour growth?

1982 • 33 citations

Immunoregulatory T-lymphocyte functions in patients with small cell lung cancer

1987 • 30 citations

The effects of α and γ interferons on human lung cancer cells grown in vitro or as xenografts in nude mice

1985 • 30 citations

Interferon is able to reduce tumor cell susceptibility to human lymphokine-activated killer (LAK) cells

1989 • 27 citations

Additive and differential biological activity of alpha-interferon A, difluoromethylornithine, and their combination on established human lung cancer cell lines.

1986 • 27 citations

Lysis by activated lymphocytes of melanoma and small cell lung cancer cells surviving in vitro treatment with mafosfamide.

1987 • 21 citations

Interferon-gamma upregulates the susceptibility of human neuroblastoma cells to interleukin-2-activated natural killer cells.

1989 • 20 citations

Effects of tumor necrosis factor, alone or in combination with topoisomerase‐ii‐targeted drugs, on human lung cancer cell lines

1990 • 18 citations

Augmentation of lymphokine-activated killer cell cytotoxicity by monoclonal antibodies against human small cell lung carcinoma

1990 • 16 citations

Cytokines in cancer therapy

1989 • 15 citations

In vitro antitumor effect of recombinant human tumor necrotizing factor on cultured human cancer cell lines and freshly isolated lung cancer cells by the human tumor clonogenic assay

1987 • 8 citations

The use of clonogenic assays in assessing the response of human lung cancer cell lines to α and γ interferons alone or in combination with adriamycin

1990 • 5 citations