Heterogeneity and cardiac arrhythmias: An overview

Right bundle branch block, persistent ST segment elevation and sudden cardiac death: A distinct clinical and electrocardiographic syndrome

1992 • 3,249 citations

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

1995 • 2,263 citations

Cardiac Electrophysiology: From Cell to Bedside

1991 • 2,234 citations

Genetic basis and molecular mechanism for idiopathic ventricular fibrillation

1998 • 1,803 citations

Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

1996 • 1,746 citations

Genotype-Phenotype Correlation in the Long-QT Syndrome

2001 • 1,708 citations

SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

1995 • 1,686 citations

CaV1.2 Calcium Channel Dysfunction Causes a Multisystem Disorder Including Arrhythmia and Autism

2004 • 1,530 citations

Mutations in the Cardiac Ryanodine Receptor Gene ( hRyR2 ) Underlie Catecholaminergic Polymorphic Ventricular Tachycardia

2001 • 1,360 citations

A computer model of atrial fibrillation

1964 • 1,343 citations

Clinical and Molecular Characterization of Patients With Catecholaminergic Polymorphic Ventricular Tachycardia

2002 • 1,138 citations

Cellular Basis for the Brugada Syndrome and Other Mechanisms of Arrhythmogenesis Associated With ST-Segment Elevation

1999 • 1,122 citations

Cellular Basis for the Normal T Wave and the Electrocardiographic Manifestations of the Long-QT Syndrome

1998 • 982 citations

Catecholaminergic Polymorphic Ventricular Tachycardia in Children

1995 • 975 citations

Mutations in Kir2.1 Cause the Developmental and Episodic Electrical Phenotypes of Andersen's Syndrome

2001 • 973 citations

The long QT syndrome. Prospective longitudinal study of 328 families.

1991 • 960 citations

Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death

2003 • 958 citations

Nonuniform Recovery of Excitability in Ventricular Muscle

1964 • 939 citations

Loss-of-Function Mutations in the Cardiac Calcium Channel Underlie a New Clinical Entity Characterized by ST-Segment Elevation, Short QT Intervals, and Sudden Cardiac Death

2007 • 921 citations

Sudden Death Associated With Short-QT Syndrome Linked to Mutations in HERG

2003 • 846 citations

Sodium Channel Blockers Identify Risk for Sudden Death in Patients With ST-Segment Elevation and Right Bundle Branch Block but Structurally Normal Hearts

2000 • 778 citations

Mutations in the hminK gene cause long QT syndrome and suppress lKs function

1997 • 763 citations

Electrophysiological remodeling in hypertrophy and heart failure

1999 • 743 citations

Mutations of the Cardiac Ryanodine Receptor (RyR2) Gene in Familial Polymorphic Ventricular Tachycardia

2001 • 726 citations

Short QT Syndrome

2003 • 706 citations

Electrophysiological Effects of Ranolazine, a Novel Antianginal Agent With Antiarrhythmic Properties

2004 • 679 citations

Idiopathic Short QT Interval:A New Clinical Syndrome?

2000 • 659 citations

Idiopathic long QT syndrome: Progress and questions

1985 • 630 citations

Mutation in the KCNQ1 Gene Leading to the Short QT-Interval Syndrome

2004 • 615 citations

The M Cell:

1999 • 606 citations

Characteristics of the Delayed Rectifier Current (I_Krand I_Ks) in Canine Ventricular Epicardial, Midmyocardial, and Endocardial Myocytes

1995 • 605 citations

Sodium Channel Block With Mexiletine Is Effective in Reducing Dispersion of Repolarization and Preventing Torsade de Pointes in LQT2 and LQT3 Models of the Long-QT Syndrome

1997 • 524 citations

The Brugada syndrome: clinical, electrophysiologic and genetic aspects

1999 • 510 citations

Mutant Caveolin-3 Induces Persistent Late Sodium Current and Is Associated With Long-QT Syndrome

2006 • 502 citations

A subpopulation of cells with unique electrophysiological properties in the deep subepicardium of the canine ventricle. The M cell.

1991 • 499 citations

Cellular Basis for the ECG Features of the LQT1 Form of the Long-QT Syndrome

1998 • 499 citations

Clinical and Genetic Heterogeneity of Right Bundle Branch Block and ST-Segment Elevation Syndrome

2000 • 456 citations

Cardiac Electrophysiology: From Cell to Bedside

2014 • 456 citations

Characteristics and Distribution of M Cells in Arterially Perfused Canine Left Ventricular Wedge Preparations

1998 • 449 citations

The Brugada Syndrome: Ionic Basis and Arrhythmia Mechanisms

2001 • 417 citations

Absence of Calsequestrin 2 Causes Severe Forms of Catecholaminergic Polymorphic Ventricular Tachycardia

2002 • 398 citations

Temporal dispersion of recovery of excitability in atrium and ventricle as a function of heart rate

1966 • 393 citations

Differential effects of beta-adrenergic agonists and antagonists in LQT1, LQT2 and LQT3 models of the long QT syndrome

2000 • 379 citations

Arrhythmic disorder mapped to chromosome 1q42–q43 causes malignant polymorphic ventricular tachycardia in structurally normal hearts

1999 • 343 citations

Drug‐Induced Torsades de Pointes and Implications for Drug Development

2004 • 338 citations

Cellular mechanisms underlying the long QT syndrome

2002 • 317 citations

Long QT syndrome: reduced repolarization reserve and the genetic link

2005 • 312 citations

T wave peak-to-end interval and QT dispersion in acquired long QT syndrome: a new index for arrhythmogenicity

2003 • 307 citations

Novel, Ultraslow Inactivating Sodium Current in Human Ventricular Cardiomyocytes

1998 • 306 citations

Assessing predictors of drug-induced torsade de pointes

2003 • 306 citations

Brugada Syndrome

2006 • 296 citations

Transmural Electrophysiological Heterogeneities Underlying Arrhythmogenesis in Heart Failure

2003 • 293 citations

The QT interval

2001 • 270 citations

Enhanced Ca ²⁺ Release and Na/Ca Exchange Activity in Hypertrophied Canine Ventricular Myocytes

2000 • 263 citations

Exercise Stress Test Amplifies Genotype-Phenotype Correlation in the LQT1 and LQT2 Forms of the Long-QT Syndrome

2003 • 256 citations

T‐peak to T‐end interval may be a better predictor of high‐risk patients with hypertrophic cardiomyopathy associated with a cardiac troponin i mutation than qt dispersion

2002 • 254 citations

Clinical and Molecular Heterogeneity in the Brugada Syndrome

2002 • 254 citations

Larger late sodium conductance in M cells contributes to electrical heterogeneity in canine ventricle

2001 • 253 citations

Downregulation of Delayed Rectifier K ⁺ Currents in Dogs With Chronic Complete Atrioventricular Block and Acquired Torsades de Pointes

1999 • 246 citations

Transmural heterogeneity of action potentials andI _to1 in myocytes isolated from the human right ventricle

1998 • 241 citations

Sodium channel gene (SCN5A) mutations in 44 index patients with Brugada syndrome: Different incidences in familial and sporadic disease

2003 • 235 citations

Effect of Sodium Channel Blockers on ST Segment, QRS Duration, and Corrected QT Interval in Patients with Brugada Syndrome

2000 • 234 citations

Common Sodium Channel Promoter Haplotype in Asian Subjects Underlies Variability in Cardiac Conduction

2006 • 230 citations

Brugada Syndrome

2002 • 221 citations

Amplified Transmural Dispersion of Repolarization as the Basis for Arrhythmogenesis in a Canine Ventricular-Wedge Model of Short-QT Syndrome

2004 • 212 citations

Phase 2 reentry as a mechanism of initiation of circus movement reentry in canine epicardium exposed to simulated ischemia

1996 • 212 citations

Transmural dispersion of repolarization and ventricular tachyarrhythmias

2004 • 197 citations

Repolarization abnormalities in cardiomyocytes of dogs with chronic heart failure: role of sustained inward current

1999 • 196 citations

Chronic Amiodarone Evokes No Torsade de Pointes Arrhythmias Despite QT Lengthening in an Animal Model of Acquired Long-QT Syndrome

2001 • 195 citations

Delay in Right Ventricular Activation Contributes to Brugada Syndrome

2004 • 187 citations

Effects of a K ⁺ Channel Opener to Reduce Transmural Dispersion of Repolarization and Prevent Torsade de Pointes in LQT1, LQT2, and LQT3 Models of the Long-QT Syndrome

2000 • 184 citations

The electrophysiologic mechanism of ST-segment elevation in Brugada syndrome

2002 • 177 citations

Role of sodium and calcium channel block in unmasking the Brugada syndrome

2004 • 160 citations

Heterogeneous connexin43 expression produces electrophysiological heterogeneities across ventricular wall

2004 • 160 citations

Phase 2 Reentry as a Trigger to Initiate Ventricular Fibrillation During Early Acute Myocardial Ischemia

2004 • 157 citations

I _NaCa contributes to electrical heterogeneity within the canine ventricle

2000 • 154 citations

Chronic Amiodarone Reduces Transmural Dispersion of Repolarization in the Canine Heart

1997 • 150 citations

The Controversial M Cell

1999 • 142 citations

Distribution of M Cells in the Canine Ventricle

1994 • 133 citations

Sodium Pentobarbital Reduces Transmural Dispersion of Repolarization and Prevents Torsades de Pointes in Models of Acquired and Congenital Long QT Syndrome

1999 • 133 citations

Cellular Basis for Complex T Waves and Arrhythmic Activity Following Combined I_Kr and I_Ks Block

2001 • 131 citations

Sympathetic stimulation produces a greater increase in both transmural and spatial dispersion of repolarization in LQT1 than LQT2 forms of congenital long QT syndrome

2001 • 131 citations

Cellular Basis for Trigger and Maintenance of Ventricular Fibrillation in the Brugada Syndrome Model

2006 • 131 citations

The Brugada syndrome: diagnostic criteria and cellular mechanisms

2001 • 125 citations

Cellular Arrhythmogenic Effects of Congenital and Acquired Long-QT Syndrome in the Heterogeneous Myocardium

2000 • 122 citations

The Brugada Syndrome: From Bench to Bedside

2005 • 121 citations

Cisapride-Induced Transmural Dispersion of Repolarization and Torsade de Pointes in the Canine Left Ventricular Wedge Preparation During Epicardial Stimulation

2003 • 120 citations

Cellular Mechanisms Underlying the Development of Catecholaminergic Ventricular Tachycardia

2005 • 108 citations

Cellular basis for ST-segment changes observed during ischemia

2003 • 73 citations

Functional and transmural modulation of M cell behavior in canine ventricular wall

2004 • 66 citations

ECG phenomenon of idiopathic and paradoxical short QT intervals.

2002 • 62 citations

Extrasystolic beats affect transmural electrical dispersion during programmed electrical stimulation

2001 • 59 citations

Temperature modulation of ventricular arrhythmogenicity in a canine tissue model of Brugada syndrome

2006 • 59 citations

Electrophysiological parameters indicative of sudden cardiac death in the dog with chronic complete AV-block

2001 • 58 citations

Cryptic 5? splice site activation in SCN5A associated with Brugada syndrome

2004 • 56 citations

Transmural Distribution of Connexins in Rodent Hearts

2004 • 52 citations

T wave alternans in an in vitro canine tissue model of Brugada syndrome

2006 • 45 citations

Within-subject electrocardiographic differences at equal heart rates: role of the autonomic nervous system

2000 • 38 citations

Conduction Abnormalities in Nonischemic Dilated Cardiomyopathy: Basic Mechanisms and Arrhythmic Consequences

2005 • 35 citations

AB16-1

2006 • 33 citations

Prior ischemia enhances arrhythmogenicity in isolated canine ventricular wedge model of long QT 3

2004 • 24 citations

Drug-induced Channelopathies

2004 • 17 citations

AB16-6

2006 • 16 citations

Cardiac Electrophysiology: From Cell to Bedside, Fourth Edition

2004 • 6 citations