Her-2/neu overexpression induces NF-κB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IκB-α that can be inhibited by the tumor suppressor PTEN

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1987 • 11,429 citations

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1997 • 4,753 citations

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1999 • 2,147 citations

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1997 • 2,137 citations

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1997 • 2,048 citations

NF-κB is a target of AKT in anti-apoptotic PDGF signalling

1999 • 1,830 citations

Pten is essential for embryonic development and tumour suppression

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1992 • 1,190 citations

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2000 • 1,150 citations

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1993 • 1,148 citations

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Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment.

1998 • 1,086 citations

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1997 • 1,075 citations

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1996 • 717 citations

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1992 • 288 citations

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1994 • 186 citations

Transformation of human breast epithelial cells by chemical carcinogens

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Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene.

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Protein-tyrosine Phosphatase ϵ

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Evidence for a role of NF-κB in the survival of hematopoietic cells mediated by interleukin 3 and the oncogenic TEL/platelet-derived growth factor receptor β fusion protein

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Recent developments in breast cancer therapy.

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2000 • 26 citations

Untitled

1997 • 23 citations

Involvement of Small GTPases in Mycoplasma fermentans Membrane Lipoproteins-mediated Activation of Macrophages

1999 • 22 citations