Synaptotagmin Interaction with the Syntaxin/SNAP-25 Dimer Is Mediated by an Evolutionarily Conserved Motif and Is Sensitive to Inositol Hexakisphosphate

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution

1998 • 2,377 citations

A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion

1993 • 1,893 citations

Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse

1994 • 1,485 citations

Syntaxin: A Synaptic Protein Implicated in Docking of Synaptic Vesicles at Presynaptic Active Zones

1992 • 1,274 citations

Neurotoxins Affecting Neuroexocytosis

2000 • 1,230 citations

Synaptotagmin I functions as a calcium regulator of release probability

2001 • 964 citations

Secretory Granule Exocytosis

2003 • 914 citations

Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C

1990 • 829 citations

Calcium Action in Synaptic Transmitter Release

1987 • 742 citations

Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold

1995 • 680 citations

The effect of calcium on acetylcholine release from motor nerve terminals

1965 • 629 citations

Synaptotagmins: Why So Many?

2002 • 497 citations

Complexins: Cytosolic proteins that regulate SNAP receptor function

1995 • 494 citations

A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding.

1993 • 486 citations

Three-Dimensional Structure of the Synaptotagmin 1 C2B-Domain

2001 • 389 citations

How does calcium trigger neurotransmitter release?

2001 • 371 citations

The C2B Ca2+-binding motif of synaptotagmin is required for synaptic transmission in vivo

2002 • 322 citations

Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin

1996 • 290 citations

Synaptotagmin I Functions as a Calcium Sensor to Synchronize Neurotransmitter Release

2002 • 286 citations

Inhibition of neurotransmitter release by C2-domain peptides implicates synaptotagmin in exocytosis

1993 • 282 citations

HPC-1 is associated with synaptotagmin and omega-conotoxin receptor.

1992 • 275 citations

Synaptotagmin II. A novel differentially distributed form of synaptotagmin

1991 • 231 citations

Synaptotagmin I, a Ca2+ sensor for neurotransmitter release

2003 • 226 citations

Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin I

2001 • 199 citations

Vesicular restriction of synaptobrevin suggests a role for calcium in membrane fusion

2002 • 197 citations

SNARE assembly and disassembly exhibit a pronounced hysteresis

2002 • 193 citations

Time course of Ca2+ concentration triggering exocytosis in neuroendocrine cells.

1994 • 191 citations

Delineation of the Oligomerization, AP-2 Binding, and Synprint Binding Region of the C2B Domain of Synaptotagmin

1998 • 180 citations

Neurotransmitter Release from Synaptotagmin-Deficient Clonal Variants of PC 12 Cells

1992 • 178 citations

Crystal Structure of the Cytosolic C2a-C2b Domains of Synaptotagmin III

1999 • 174 citations

Regulated exocytosis and SNARE function (Review)

2003 • 173 citations

Functional Diversity of C2 Domains of Synaptotagmin Family

1995 • 170 citations

Mechanisms Determining the Time Course of Secretion in Neuroendocrine Cells

1996 • 149 citations

The C₂B Domain of Synaptotagmin I Is a Ca²⁺-Binding Module

2001 • 131 citations

Complexin Regulates the Closure of the Fusion Pore during Regulated Vesicle Exocytosis

2002 • 127 citations

Mechanism of Calcium-independent Synaptotagmin Binding to Target SNAREs

2003 • 99 citations

Synaptotagmin IX Regulates Ca2+-dependent Secretion in PC12 Cells

2002 • 98 citations

Synaptotagmins in membrane traffic: Which vesicles do the tagmins tag?

2000 • 96 citations

The inositol high-polyphosphate series blocks synaptic transmission by preventing vesicular fusion: a squid giant synapse study.

1994 • 94 citations

High Affinity Interaction of Syntaxin and SNAP-25 on the Plasma Membrane Is Abolished by Botulinum Toxin E

2003 • 93 citations

Mutations in the second C2 domain of synaptotagmin disrupt synaptic transmission at Drosophila neuromuscular junctions.

2001 • 89 citations

Membrane-embedded Synaptotagmin Penetrates cis ortrans Target Membranes and Clusters via a Novel Mechanism

2000 • 89 citations

Visualization of synaptotagmin I oligomers assembled onto lipid monolayers

2003 • 80 citations

Mutations in the second C₂ domain of synaptotagmin disrupt synaptic transmission at Drosophila neuromuscular junctions

2001 • 80 citations

Role of the conserved WHXL motif in the C terminus of synaptotagmin in synaptic vesicle docking

2000 • 68 citations

Phosphoinositides as Key Regulators of Synaptic Function

2001 • 63 citations

Glycerotoxin from Glycera convoluta stimulates neurosecretion by up-regulating N-type Ca2+ channel activity

2002 • 53 citations

Neurotransmitter Release

1999 • 30 citations

Mouse motor nerve terminal immunoreactivity to synaptotagmin II during sustained quantal transmitter release

1995 • 15 citations

Synaptotagmin II immunoreactivity in normal and botulinum type-A treated mouse motor nerve terminals

1996 • 15 citations