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1995 • 632 citations

The Rotarod Test: An Evaluation of Its Effectiveness in Assessing Motor Deficits Following Traumatic Brain Injury

1994 • 616 citations

TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination

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Experimental Brain Injury Induces Regionally Distinct Apoptosis during the Acute and Delayed Post-Traumatic Period

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1993 • 517 citations

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1995 • 517 citations

DIFFERENTIAL REGULATION OF PRO-INFLAMMATORY CYTOKINES DURING WOUND HEALING IN NORMAL AND GLUCOCORTICOID-TREATED MICE

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Evaluation of Memory Dysfunction Following Experimental Brain Injury Using the Morris Water Maze

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TNF-α Pretreatment Induces Protective Effects against Focal Cerebral Ischemia in Mice

1997 • 346 citations

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Temporal and spatial characterization of neuronal injury following lateral fluid-percussion brain injury in the rat

1996 • 289 citations

Neutrophil Accumulation After Traumatic Brain Injury in Rats: Comparison of Weight Drop and Controlled Cortical Impact Models

1994 • 285 citations

Inhibition of Tumor Necrosis Factor Alpha (TNFα) Activity in Rat Brain is Associated with Cerebroprotection after Closed Head Injury

1996 • 284 citations

Tumor necrosis factor-α-induced gelatinase B causes delayed opening of the blood-brain barrier: an expanded therapeutic window

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Tumor Necrosis Factor-Alpha Potentiates Glutamate Neurotoxicity in Human Fetal Brain Cell Cultures

1994 • 243 citations

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Oxidative Stress in Closed-Head Injury: Brain Antioxidant Capacity as an Indicator of Functional Outcome

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Experimental brain injury induces differential expression of tumor necrosis factor-α mRNA in the CNS

1996 • 242 citations

Cytokine modulation of glial glutamate uptake

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Apoptotic morphology of dentate gyrus granule cells following experimental cortical impact injury in rats: possible role in spatial memory deficits

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Inhibition of tumor necrosis factor-alpha reduces focal cerebral ischemic injury in the spontaneously hypertensive rat

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Circulating Antibody against Tumor Necrosis Factor–Alpha Protects Rat Brain from Reperfusion Injury

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Defective Peyer's patch organogenesis in mice lacking the 55-kD receptor for tumor necrosis factor.

1996 • 181 citations

Localization of TNFα and IL-1a immunoreactivities in striatal neurons after surgical injury to the hippocampus

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Neurotoxic Effects of Tumor Necrosis Factor Alpha in Primary Human Neuronal Cultures are Mediated by Activation of the Glutamate AMPA Receptor Subtype: Implications for AIDS Neuropathogenesis

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Attenuation of acute and chronic damage following traumatic brain injury in copper, zinc—superoxide dismutase transgenic mice

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Protective roles of cytokines against radiation: Induction of mitochondrial MnSOD

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The HIV envelope protein gp120 is toxic to human brain-cell cultures through the induction of interleukin-6 and tumor necrosis factor-α

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Tumor necrosis factor stimulates the synthesis and secretion of biologically active nerve growth factor in non-neuronal cells.

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The presence of tumour necrosis factor in CSF and plasma after severe head injury

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The HIV envelope protein gp120 is toxic to human brain-cell cultures through the induction of interleukin-6 and tumor necrosis factor-α

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Formation of Ion-Permeable Channels by Tumor Necrosis Factor-α

1992 • 143 citations

Brain injury and tumor necrosis factors induce calbindin D‐28K in astrocytes: Evidence for a cytoprotective response

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BCL-2 Overexpression Attenuates Cortical Cell Loss after Traumatic Brain Injury in Transgenic Mice

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Regulation of GDNF expression in cultured astrocytes by inflammatory stimuli

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Calcium Movements in Traumatic Brain Injury: The Role of Glutamate Receptor-Operated Ion Channels

1996 • 118 citations

Persistent memory dysfunction is associated with bilateral hippocampal damage following experimental brain injury

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Twofold overexpression of human ?-amyloid precursor proteins in transgenic mice does not affect the neuromotor, cognitive, or neurodegenerative sequelae following experimental brain injury

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Peripheral Blood Mononuclear Cells Induce Programmed Cell Death in Human Endothelial Cells and May Prevent Repair: Role of Cytokines

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Accumulation of calcium in the brain following head trauma

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Toxicity of TNFα and platelet activating factor for human NT2N neurons: A tissue culture model for human immunodeficiency virus dementia

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TNFα gene expression is induced in neurones after a hippocampal lesion

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Histological and functional evaluation of experimental spinal cord injury: evidence of a stepwise response to graded compression

1996 • 68 citations

Tumor necrosis factor induces genes involved in inflammation, cellular and tissue repair, and metabolism in murine fibroblasts.

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An endogenous 55 kDa TNF receptor mediates cell death in a neural cell line

1996 • 62 citations

Inhibition of tumor necrosis factor is protective against neurologic dysfunction after active immunization of lewis rats with myelin basic protein

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TNF-α increases the frequency of spontaneous miniature synaptic currents in cultured rat hippocampal neurons

1994 • 59 citations

Structural changes of tumor necrosis factor alpha associated with membrane insertion and channel formation.

1996 • 59 citations

TNF and related molecules: trends in neuroscience and clinical applications1This is a Meeting report from the 6th International TNF Congress: TNF and Related Molecules, Scientific Trends and Clinical Applications. Abstracts are published in European Cytokine Network 7 (1996) 143–346.1

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Expression of TNF? in central neurons of Lewis rat spinal cord after EAE induction

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TUMOR NECROSIS FACTOR PROMOTES MOTOR FUNCTIONAL RECOVERY IN CRUSHED PERIPHERAL NERVE

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8 Down-regulation of cytokine action

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