Reversing the Inactivation of Peroxiredoxins Caused by Cysteine Sulfinic Acid Formation

Protein Oxidation and Aging

1992 • 2,687 citations

Oxygen radicals and signaling

1998 • 1,163 citations

Thioredoxin-dependent peroxide reductase from yeast.

1994 • 940 citations

Cloning and sequencing of thiol-specific antioxidant from mammalian brain: alkyl hydroperoxide reductase and thiol-specific antioxidant define a large family of antioxidant enzymes.

1994 • 743 citations

Mammalian Peroxiredoxin Isoforms Can Reduce Hydrogen Peroxide Generated in Response to Growth Factors and Tumor Necrosis Factor-α

1998 • 672 citations

Peroxiredoxin, a Novel Family of Peroxidases

2001 • 616 citations

Protein-Sulfenic Acids: Diverse Roles for an Unlikely Player in Enzyme Catalysis and Redox Regulation

1999 • 489 citations

Hypochlorous Acid Oxygenates the Cysteine Switch Domain of Pro-matrilysin (MMP-7)

2001 • 473 citations

Inactivation of Human Peroxiredoxin I during Catalysis as the Result of the Oxidation of the Catalytic Site Cysteine to Cysteine-sulfinic Acid

2002 • 449 citations

Regulatory Role for a Novel Human Thioredoxin Peroxidase in NF-κB Activation

1997 • 414 citations

Proteomics Analysis of Cellular Response to Oxidative Stress

2002 • 388 citations

Thioredoxin Peroxidase Is a Novel Inhibitor of Apoptosis with a Mechanism Distinct from That of Bcl-2

1997 • 372 citations

Dimerization of thiol-specific antioxidant and the essential role of cysteine 47.

1994 • 309 citations

Crystal structure of decameric 2-Cys peroxiredoxin from human erythrocytes at 1.7Å resolution

2000 • 296 citations

Oxidation of Methionine in Proteins: Roles in Antioxidant Defense and Cellular Regulation

2000 • 284 citations

Identification of Proteins Containing Cysteine Residues That Are Sensitive to Oxidation by Hydrogen Peroxide at Neutral pH

2000 • 271 citations

Crystal structure of a multifunctional 2-Cys peroxiredoxin heme-binding protein 23 kDa/proliferation-associated gene product

1999 • 255 citations

Characterization of a Two-component Alkanesulfonate Monooxygenase from Escherichia coli

1999 • 211 citations

Post‐translational modification is essential for catalytic activity of nitrile hydratase

2000 • 153 citations

Mechanisms and Reactivity in Reactions of Organic Oxyacids of Sulfur and their Anhydrides

1980 • 121 citations

Variants of peroxiredoxins expression in response to hydroperoxide stress

2001 • 118 citations

Production methods for gene transfer vectors based on adeno-associated virus serotypes

2002 • 114 citations

Hydrogen Peroxide: A Key Messenger That Modulates Protein Phosphorylation Through Cysteine Oxidation

2000 • 97 citations

[15] Quantitation of protein sulfinic and sulfonic acid, irreversibly oxidized protein cysteine sites in cellular proteins

2002 • 79 citations

Intracellular glutathione is a cofactor in methylseleninic acid-induced apoptotic cell death of human hepatoma HEPG2 cells

2002 • 43 citations