Cloning and sequencing of thiol-specific antioxidant from mammalian brain: alkyl hydroperoxide reductase and thiol-specific antioxidant define a large family of antioxidant enzymes.

Free radicals in biology and medicine

1991 • 17,840 citations

Bacterial evolution

1987 • 2,303 citations

Complementary DNA Sequencing: Expressed Sequence Tags and Human Genome Project

1991 • 2,286 citations

Strategies of antioxidant defense

1993 • 1,963 citations

Large scale cDNA sequencing for analysis of quantitative and qualitative aspects of gene expression

1992 • 528 citations

The isolation and purification of a specific “protector” protein which inhibits enzyme inactivation by a thiol/Fe(III)/O2 mixed-function oxidation system.

1988 • 483 citations

[23] Progressive alignment and phylogenetic tree construction of protein sequences

1990 • 350 citations

An Alkyl Hydroperoxide Reductase from Salmonella typhimurium Involved in the Defense of DNA against Oxidative Damage

1989 • 337 citations

Dimerization of thiol-specific antioxidant and the essential role of cysteine 47.

1994 • 309 citations

Cloning, sequencing, and mutation of thiol-specific antioxidant gene of Saccharomyces cerevisiae

1993 • 299 citations

An alkyl hydroperoxide reductase induced by oxidative stress in Salmonella typhimurium and Escherichia coli: genetic characterization and cloning of ahp

1989 • 261 citations

Spontaneous mutagenesis and oxidative damage to DNA in Salmonella typhimurium.

1987 • 222 citations

Cloning and characterization of a 23-kDa stress-induced mouse peritoneal macrophage protein.

1993 • 192 citations

A human cDNA corresponding to a gene overexpressed during cell proliferation encodes a product sharing homology with amoebic and bacterial proteins

1993 • 182 citations

Removals of Hydrogen Peroxide and Hydroxyl Radical by Thiol-Specific Antioxidant Protein as a Possible Role in Vivo

1993 • 178 citations

Alkyl hydroperoxide reductase from Salmonella typhimurium. Sequence and homology to thioredoxin reductase and other flavoprotein disulfide oxidoreductases.

1990 • 173 citations

Sequence of thioredoxin reductase from Escherichia coli. Relationship to other flavoprotein disulfide oxidoreductases.

1988 • 137 citations

Induction of an antioxidant protein of Saccharomyces cerevisiae by O2, Fe3+, or 2-mercaptoethanol.

1989 • 134 citations

Overproduction of peroxide-scavenging enzymes in Escherichia coli suppresses spontaneous mutagenesis and sensitivity to redox-cycling agents in oxyR-mutants.

1988 • 128 citations

Isolation and biochemical and molecular analyses of a species-specific protein antigen from the gastric pathogen Helicobacter pylori

1991 • 120 citations

Cloning of a housekeeping-type gene (MERS) preferentially expressed in murine erythroleukemia cells

1989 • 110 citations

On the protective mechanism of the thiol-specific antioxidant enzyme against the oxidative damage of biomacromolecules.

1994 • 104 citations

Molecular cloning and analysis of the gene encoding the NADH oxidase from Streptococcus faecalis 10C1

1992 • 102 citations

Cloning and expression of an embryo-specific mRNA up-regulated in hydrated dormant seeds

1992 • 96 citations

cDNA sequence analysis of a 29-kDa cysteine-rich surface antigen of pathogenic Entamoeba histolytica.

1990 • 84 citations

Cloning, sequencing and expression in Escherichia coli of the rubredoxin gene from Clostridium pasteurianum

1992 • 67 citations

Identification of Natural Killer-Enhancing Factor as a Major Antioxidant in Human Red Blood Cells

1994 • 66 citations

Non-selenium glutathione peroxidase without glutathione S-transferase activity from bovine ciliary body

1990 • 62 citations

The Non-flavin Redox Center of the Streptococcal NADH Peroxidase

1989 • 48 citations

Characterization of a superoxide dismutase gene from the archaebacterium Methanobacterium thermoautotrophicum

1990 • 38 citations

Nucleotide Sequence of the Gene Encoding NADH Dehydrogenase from an Alkalophile, Bacillus sp. Strain YN-1

1991 • 38 citations

A molecular analysis of the 53.3 minute region of the Escherichia coli linkage map

1991 • 31 citations

Molecular analysis of the Bacteroides fragilis recA gene

1990 • 26 citations

The Pseudomonas cepacia 249 chromosomal penicillinase is a member of the AmpC family of chromosomal beta-lactamases

1993 • 23 citations

Cloning and expression of the gene for the Avi-3 antigen of Mycobacterium avium and mapping of its epitopes

1992 • 22 citations

Sequence of peptides from Saccharomyces cerevisiae glutamine synthetase. N-terminal peptide and ATP-binding domain.

1988 • 14 citations

Tryptic Digestion of NADH Dehydrogenase from Alkalophilic Bacillus1

1989 • 8 citations