Structure of LEP100, a glycoprotein that shuttles between lysosomes and the plasma membrane, deduced from the nucleotide sequence of the encoding cDNA.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed Recombinants

1964 • 2,108 citations

Intracellular protein topogenesis

1980 • 1,378 citations

pEMBL: a new family of single stranded plasmids

1983 • 1,231 citations

[17] Isolation of microgram quantities of proteins from polyacrylamide gels for amino acid sequence analysis

1983 • 1,115 citations

Purification and Properties of an Endo-β-N-acetylglucosaminidase from Streptomyces griseus

1974 • 870 citations

[36] High-sensitivity sequencing with a gas-phase sequenator

1983 • 670 citations

Deletion of thymidine kinase activity from L cells resistant to bromodeoxyuridine

1963 • 611 citations

The nucleotide sequence and transcript map of the herpes simplex virus thymidine kinase gene

1980 • 556 citations

Identification of two lysosomal membrane glycoproteins.

1985 • 475 citations

Expression of recombinant plasmids in mammalian cells Is enhanced by sodium butyrate

1983 • 380 citations

An alternative approach to deoxyoligonucleotides as hybridization probes by insertion of deoxyinosine at ambiguous codon positions.

1985 • 305 citations

Novel mannosidase inhibitor blocking conversion of high mannose to complex oligosaccharides

1984 • 304 citations

Glycoproteins of the lysosomal membrane.

1985 • 294 citations

Cycling of the integral membrane glycoprotein, LEP100, between plasma membrane and lysosomes: Kinetic and morphological analysis

1987 • 244 citations

Molecular Mechanisms of Protein Secretion: The Role of the Signal Sequence

1986 • 222 citations

Biosynthesis, glycosylation, movement through the Golgi system, and transport to lysosomes by an N-linked carbohydrate-independent mechanism of three lysosomal integral membrane proteins.

1986 • 212 citations

Lysosomal membrane dynamics: structure and interorganellar movement of a major lysosomal membrane glycoprotein.

1986 • 193 citations

The (Na+ + K+)-ATPase of chick sensory neurons. Studies on biosynthesis and intracellular transport.

1986 • 169 citations

Tissue distribution, structural characterization, and biosynthesis of Mac-3, a macrophage surface glycoprotein exhibiting molecular weight heterogeneity.

1983 • 151 citations

The use of 1-deoxymannojirimycin to evaluate the role of various alpha-mannosidases in oligosaccharide processing in intact cells.

1986 • 137 citations

Antibodies against lysosomal membranes reveal a 100,000-mol-wt protein that cross-reacts with purified H+,K+ ATPase from gastric mucosa.

1984 • 96 citations

Expression of hybrid (Na+ + K+)-ATPase molecules after transfection of mouse Ltk-cells with DNA encoding the beta-subunit of an avian brain sodium pump.

1987 • 93 citations

Nucleotide Sequence Analysis of Deoxyribonucleic Acid

1972 • 40 citations

Expression of cotransferred genes in mouse L cells

1984 • 10 citations