Store-operated Ca2+ influx: What is the message from the stores to the membrane?

Inositol trisphosphate and calcium signalling

1993 • 6,546 citations

A model for receptor-regulated calcium entry

1986 • 2,535 citations

Depletion of intracellular calcium stores activates a calcium current in mast cells

1992 • 1,748 citations

Heterotrimeric C proteins: Organizers of transmembrane signals

1995 • 1,388 citations

Molecular characterization of the drosophila trp locus: A putative integral membrane protein required for phototransduction

1989 • 1,119 citations

The structure and function of proline-rich regions in proteins

1994 • 965 citations

Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx

1993 • 892 citations

Activation of Calcium Entry by the Tumor Promoter Thapsigargin in Parotid Acinar Cells

1989 • 887 citations

The Cellular Functions of Small GTP-Binding Proteins

1990 • 881 citations

Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores.

1993 • 752 citations

‘Quanta’ Ca²⁺ release and the control of Ca²⁺ entry by inositol phosphates ‐ a possible mechanism

1990 • 743 citations

Calcium release‐activated calcium current in rat mast cells.

1993 • 729 citations

TRPC1, a human homolog of a Drosophila store-operated channel.

1995 • 623 citations

Regions of the skeletal muscle dihydropyridine receptor critical for excitation–contraction coupling

1990 • 606 citations

CALCIUM CHANNELS: Mechanisms of Selectivity, Permeation, and Block

1987 • 528 citations

Regulation of calcium influx by second messengers in rat mast cells

1988 • 506 citations

Receptor-activated Ca2+ influx: how many mechanisms for how many channels?

1994 • 403 citations

Depletion of InsP3 stores activates a Ca2+ and K+ current by means of a phosphatase and a diffusible messenger

1993 • 363 citations

A novel tumour promoter, thapsigargin, transiently increases cytoplasmic free Ca2+ without generation of inositol phosphates in NG115-401L neuronal cells

1988 • 344 citations

Ionomycin enhances Ca2+ influx by stimulating store-regulated cation entry and not by a direct action at the plasma membrane

1994 • 305 citations

Uptake and intracellular sequestration of divalent cations in resting and methacholine-stimulated mouse lacrimal acinar cells. Dissociation by Sr2+ and Ba2+ of agonist-stimulated divalent cation entry from the refilling of the agonist-sensitive intracellular pool.

1990 • 298 citations

Exchange characteristics of the noradrenaline‐sensitive calcium store in vascular smooth muscle cells or rabbit ear artery.

1981 • 291 citations

A GTP-dependent step in the activation mechanism of capacitative calcium influx.

1993 • 283 citations

Cyclopiazonic acid depletes intracellular Ca2+ stores and activates an influx pathway for divalent cations in HL-60 cells.

1992 • 271 citations

Novel Ca2+ channels underlying transduction in Drosophila photoreceptors: implications for phosphoinositide-mediated Ca2+ mobilization

1993 • 262 citations

Intracellular Ca2+ pool content is linked to control of cell growth.

1993 • 260 citations

Coupling between intracellular Ca2+ stores and the Ca2+ permeability of the plasma membrane. Comparison of the effects of thapsigargin, 2,5-di-(tert-butyl)-1,4-hydroquinone, and cyclopiazonic acid in rat thymic lymphocytes.

1991 • 243 citations

Capacitative calcium entry in parotid acinar cells

1989 • 234 citations

Activation of recombinant trp by thapsigargin in Sf9 insect cells

1994 • 226 citations

Effects of MeCh, thapsigargin, and La3+ on plasmalemmal and intracellular Ca2+ transport in lacrimal acinar cells

1990 • 207 citations

Inhibition of bradykinin- and thapsigargin-induced Ca2+ entry by tyrosine kinase inhibitors

1993 • 206 citations

Putative capacitative calcium entry channels: expression of Drosophila trp and evidence for the existence of vertebrate homologues

1995 • 193 citations

ADP- and thapsigargin-evoked Ca2+ entry and protein-tyrosine phosphorylation are inhibited by the tyrosine kinase inhibitors genistein and methyl-2,5-dihydroxycinnamate in fura-2-loaded human platelets.

1993 • 191 citations

Depletion of the inositol 1,4,5-trisphosphate-sensitive intracellular Ca2+ store in vascular endothelial cells activates the agonist-sensitive Ca2+-influx pathway

1992 • 190 citations

Depletion of intracellular Ca2+ stores activates nitric-oxide synthase to generate cGMP and regulate Ca2+ influx.

1994 • 179 citations

Cytosolic and stored calcium antagonistically control tyrosine phosphorylation of specific platelet proteins.

1991 • 170 citations

Depletion-activated calcium current is inhibited by protein kinase in RBL-2H3 cells.

1995 • 166 citations

Cytochrome P-450 may link intracellular Ca2+ stores with plasma membrane Ca2+ influx

1991 • 164 citations

Inhibition of protein synthesis and early protein processing by thapsigargin in cultured cells

1993 • 157 citations

Subcellular distribution of the calcium-storing inositol 1,4,5-trisphosphate-sensitive organelle in rat liver. Possible linkage to the plasma membrane through the actin microfilaments

1991 • 144 citations

Cyclic GMP mediates the agonist-stimulated increase in plasma membrane calcium entry in the pancreatic acinar cell.

1990 • 138 citations

Redistribution of intracellular Ca2+ stores during phagocytosis in human neutrophils

1994 • 136 citations

Degradation of a Calcium Influx Factor (CIF) Can Be Blocked by Phosphatase Inhibitors or Chelation of Ca2+

1995 • 134 citations

Inhibition of Ca2+ transport pathways in thymic lymphocytes by econazole, miconazole, and SKF 96365

1993 • 133 citations

Calcium channels activated by depletion of internal calcium stores in A431 cells

1994 • 131 citations

Cyclic GMP modulates depletion-activated Ca2+ entry in pancreatic acinar cells

1993 • 130 citations

Direct G Protein Activation of Ion Channels?

1994 • 127 citations

Activation of Ca2+ current in Jurkat T cells following the depletion of Ca2+ stores by microsomal Ca(2+)-ATPase inhibitors.

1994 • 123 citations

The route of Ca2+ entry during reloading of the intracellular Ca2+ pool in pancreatic acini.

1990 • 104 citations

Agonist-induced Ca2+ influx into human platelets is secondary to the emptying of intracellular Ca2+ stores

1991 • 100 citations

Calcium influx evoked by Ca2+ store depletion in human platelets is more susceptible to cytochrome P-450 inhibitors than receptor-mediated calcium entry

1992 • 97 citations

Primaquine, an inhibitor of vesicular transport, blocks the calcium-release-activated current in rat megakaryocytes

1995 • 94 citations

Modulation of Ca2+ influx dependent on store depletion by intracellular adenine-guanine nucleotide levels.

1994 • 87 citations

Evaluation of Calcium Influx Factors from Stimulated Jurkat T-lymphocytes by Microinjection into Xenopus Oocytes

1995 • 86 citations

Refill status of the agonist-sensitive Ca2+ pool regulates Mn2+ influx into parotid acini.

1990 • 78 citations

Tyrosine Kinase Inhibitors Attenuate "Capacitative" Ca2+ Influx in Rat Pancreatic Acinar Cells

1994 • 71 citations

The COOH-terminal Domain of Drosophila TRP Channels Confers Thapsigargin Sensitivity

1996 • 65 citations

Protein kinase C activates capacitative calcium entry in the insulin secreting cell line RINm5F

1994 • 64 citations

Vectorial Ca2+ flux from the extracellular space to the endoplasmic reticulum via a restricted cytoplasmic compartment regulates inositol 1,4,5-trisphosphate-stimulated Ca2+ release from internal stores in vascular endothelial cells

1993 • 64 citations

Multiple mechanisms of manganese-induced quenching of fura-2 fluorescence in rat mast cells

1993 • 64 citations

TRP, a protein essential for inositide-mediated Ca2+ influx is localized adjacent to the calcium stores in Drosophila photoreceptors

1995 • 63 citations

The regulation of store-dependent Ca2+ influx in HL-60 granulocytes involves GTP-sensitive elements.

1993 • 63 citations

Kinetics of empty store-activated Ca2+ influx in HeLa cells.

1994 • 55 citations

Phosphorylation down-regulates the store-operated Ca2+ entry pathway of human neutrophils.

1994 • 55 citations

G-protein regulation of capacitative calcium entry may be mediated by protein kinases A and C in Xenopus oocytes

1995 • 55 citations

Chromatographic Resolution of an Intracellular Calcium Influx Factor from Thapsigargin-activated Jurkat Cells

1995 • 51 citations

ATP depletion inhibits capacitative Ca2+ entry in rat thymic lymphocytes

1995 • 50 citations

The effect of calcium-store depletion and refilling with various bivalent cations on tyrosine phosphorylation and Mn2+ entry in fura-2-loaded human platelets

1994 • 49 citations

Indirect regulation of Ca²⁺ entry by cAMP‐dependent and cGMP‐dependent protein kinases and phospholipase C in rat platelets

1994 • 48 citations

Pharmacology of a Ca2+-influx pathway activated by emptying the intracellular Ca2+ stores in HL-60 cells: evidence that a cytochrome P-450 is not involved

1994 • 43 citations

ω-conotoxin and Cd2+ stimulate the recruitment to the plasmamembrane of an intracellular pool of voltage-operated Ca2+ channels

1994 • 42 citations

An intracellular calcium store regulates protein synthesis in HeLa cells, but it is not the hormone-sensitive store

1992 • 39 citations

Calcium signalling

1990 • 39 citations

Inhibition of the calcium store-operated calcium entry pathway by chemotactic peptide and by phorbol ester develops gradually and independently along differentiation of HL60 cells.

1993 • 37 citations

Role of cyclic GMP in the control of capacitative Ca2+ entry in rat pancreatic acinar cells

1995 • 36 citations

Agonist-induced inhibition of phosphatidylserine synthesis is secondary to the emptying of intracellular Ca2+ stores in Jurkat T-cells

1992 • 36 citations

Evidence That the Pertussis Toxin-sensitive Trimeric GTP-binding Protein Gi2 Is Required for Agonist- and Store-activated Ca2+ Inflow in Hepatocytes

1995 • 35 citations

Comparative effects of cytochrome P-450 inhibitors on Ca2+ and Mn2+ entry induced by agonists or by emptying the Ca2+ stores of human neutrophils

1993 • 33 citations

Department of Physiology, Box 642, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, U.S.A

1990 • 32 citations

A Soluble Cellular Factor Directly Stimulates Ca2+ Entry in Neutrophils

1995 • 32 citations

Pharmacology of the Respiratory Tract

1994 • 32 citations

Receptor-mediated Mn2+ influx in rat hepatocytes: comparison of cells loaded with Fura-2 ester and cells microinjected with Fura-2 salt

1994 • 29 citations

Evidence from studies with hepatocyte suspensions that store-operated Ca2+ inflow requires a pertussis toxin-sensitive trimeric G-protein

1994 • 28 citations

Molecular Properties of Voltage-Dependent Ca<sup>2+</sup> Channels in Excitable Tissues

1993 • 26 citations

A role for a pertussis toxin‐sensitive trimeric G‐protein in store‐operated Ca²⁺ inflow in hepatocytes

1994 • 23 citations

LU52396, an inhibitor of the store-dependent (capacitative) Ca2+ influx

1995 • 18 citations

Inhibition by a receptor-mediated Ca2+ entry blocker, SK & F 96365, of Ca2+ and secretory responses in rat pancreatic acini

1993 • 12 citations

Cyclic-GMP-dependent protein kinase in smooth muscle and neutrophils.

1993 • 11 citations

Calcium signalling: comparison of the role of Ca2+ influx in excitable endocrine and non-excitable myeloid cells.

1993 • 4 citations