Granulocytic differentiation of HL‐60 cells results in spontaneous apoptosis mediated by increased caspase expression

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

1991 • 4,682 citations

The Fas Death Factor

1995 • 4,070 citations

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1988 • 3,194 citations

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

1994 • 2,575 citations

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme

1993 • 2,484 citations

Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages.

1989 • 1,540 citations

Protease activation during apoptosis: Death by a thousand cuts?

1995 • 1,335 citations

bcl-2-Immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

1989 • 1,252 citations

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2

1994 • 1,145 citations

Molecular Cloning of the Interleukin-1β Converting Enzyme

1992 • 1,115 citations

Bcl-2 initiates a new category of oncogenes: regulators of cell death

1992 • 1,078 citations

Bcl-2 initiates a new category of oncogenes: regulators of cell death

1992 • 860 citations

Involvement of an ICE-like protease in Fas-mediated apoptosis

1995 • 757 citations

Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators

1993 • 726 citations

Prevention of Vertebrate Neuronal Death by the crmA Gene

1994 • 618 citations

Programmed Cell Death in the Immune System

1991 • 575 citations

Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils.

1996 • 574 citations

CPP32/Apopain Is a Key Interleukin 1β Converting Enzyme-like Protease Involved in Fas-mediated Apoptosis

1996 • 480 citations

HL-60 cells induced to differentiate towards neutrophils subsequently die via apoptosis

1990 • 390 citations

Differential expression of bcl-2 and susceptibility to anti-Fas- mediated cell death in peripheral blood lymphocytes, monocytes, and neutrophils

1994 • 320 citations

Neutrophils undergo apoptosis following ingestion of Escherichia coli.

1996 • 303 citations

bcl-2 proto-oncogene expression in normal and neoplastic human myeloid cells

1992 • 276 citations

Activation of Multiple Interleukin-1β Converting Enzyme Homologues in Cytosol and Nuclei of HL-60 Cells during Etoposide-induced Apoptosis

1997 • 211 citations

Regulation of bcl-2 Proto-Oncogene Expression During Normal Human Lymphocyte Proliferation

1987 • 202 citations

A Pre-aspartate-specific Protease from Human Leukocytes That Cleaves Pro-interleukin-1 β

1989 • 174 citations

Further characterization of the neutrophil oxidative burst by flow cytometry

1993 • 159 citations

Selective Activation of Caspases During Apoptotic Induction in HL-60 Cells

1997 • 138 citations

Regulation of apoptosis in neutrophils--Fas track to death?

1995 • 127 citations

Thiol-mediated redox regulation of neutrophil apoptosis

1996 • 104 citations

The efficacy of 9-cis retinoic acid in experimental models of cancer

1996 • 80 citations

Intracellular IL-1beta is an inhibitor of Fas-mediated apoptosis.

1996 • 67 citations

Defective Rho GTPase regulation by IL-1 beta-converting enzyme-mediated cleavage of D4 GDP dissociation inhibitor.

1996 • 48 citations

Role of serine and ICE-like proteases in induction of apoptosis by etoposide in human leukemia HL-60 cells.

1996 • 29 citations

Development of a H(+)-selective conductance during granulocytic differentiation of HL-60 cells

1994 • 26 citations

Mechanism of bcl-2 activation in human follicular lymphoma.

1990 • 20 citations

Regulation of cytoplasmic pH in resident and activated peritoneal macrophages

1990 • 19 citations

Retinoids and differentiation treatment: a strategy for treatment in cancer.

1994 • 9 citations

Retrovirus-mediated transfer of nuclear factor-kappa B subunit genes modulates I kappa B alpha and interferon beta expression.

1995 • 8 citations