Engineering Human Prolactin to Bind to the Human Growth Hormone Receptor

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Growth hormone receptor and serum binding protein: purification, cloning and expression

1987 • 1,540 citations

High-Resolution Epitope Mapping of hGH-Receptor Interactions by Alanine-Scanning Mutagenesis

1989 • 1,357 citations

Replacing the complementarity-determining regions in a human antibody with those from a mouse

1986 • 1,356 citations

Ultraviolet spectra Of Proteins and Amino Acids

1963 • 952 citations

Oligonucleotide-directed mutagenesis using M13-derived vectors: an efficient and general procedure for the production of point mutations in any fragment of DNA

1982 • 764 citations

A New Sensitive and Specific Bioassay for Lactogenic Hormones: Measurement of Prolactin and Growth Hormone in Human Serum*

1980 • 574 citations

Different base/base mismatches are corrected with different efficiencies by the methyl-directed DNA mismatch-repair system of E. coli

1984 • 468 citations

Three-dimensional structure of a genetically engineered variant of porcine growth hormone.

1987 • 457 citations

Mode of Action of Pituitary Growth Hormone on Target Cells

1985 • 452 citations

Structural Features of Prolactins and Growth Hormones That Can Be Related to Their Biological Properties*

1986 • 350 citations

Receptor and Antibody Epitopes in Human Growth Hormone Identified by Homolog-Scanning Mutagenesis

1989 • 345 citations

Human prolactin. cDNA structural analysis and evolutionary comparisons.

1981 • 336 citations

A Specific, Highly Active Malate Dehydrogenase by Redesign of a Lactate Dehydrogenase Framework

1988 • 276 citations

Rabbit liver growth hormone receptor and serum binding protein. Purification, characterization, and sequence.

1988 • 190 citations

Changing the binding specificity of a represser by redesigning an α-helix

1985 • 176 citations

Role of primary structure and disulfide bond formation in beta-lactamase secretion

1983 • 170 citations

The human growth hormone receptor. Secretion from Escherichia coli and disulfide bonding pattern of the extracellular binding domain.

1990 • 164 citations

Nonenzymic reactivation of reduced bovine pancreatic ribonuclease by air oxidation and by glutathione oxidoreduction buffers.

1975 • 159 citations

High-level secretion of human growth hormone by Escherichia coli

1987 • 150 citations

Importance of hydrogen-bond formation in stabilizing the transition state of subtilisin

1986 • 136 citations

Purified human growth hormone from E. coli is biologically active

1981 • 136 citations

Recruitment of substrate-specificity properties from one enzyme into a related one by protein engineering.

1987 • 134 citations

Structural Variants of Human Growth Hormone: Biochemical, Genetic, and Clinical Aspects

1983 • 120 citations

Purification and characterization of recombinant single-chain urokinase produced in Escherichia coli

1986 • 47 citations

Circular Dichroism of Pituitary Hormones

1979 • 22 citations