Damage to DNA by UV light and activation of transcription factors

ras oncogenes in human cancer: a review.

1989 • 5,116 citations

Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line.

1988 • 4,008 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

1990 • 1,605 citations

Phosphorylation of c-jun mediated by MAP kinases

1991 • 1,495 citations

Signal transduction via the MAP kinases: proceed at your own RSK.

1993 • 1,262 citations

Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

1991 • 1,071 citations

Oncogene jun encodes a sequence-specific trans- activator similar to AP-1

1988 • 940 citations

The mammalian ultraviolet response is triggered by activation of src tyrosine kinases

1992 • 874 citations

Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences

1985 • 871 citations

Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

1991 • 800 citations

Rapid and preferential activation of the c-jun gene during the mammalian UV response.

1991 • 685 citations

Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain

1991 • 626 citations

UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein.

1989 • 549 citations

The ability of a ternary complex to form over the serum response element correlates with serum inducibility of the human c-fos promoter

1989 • 495 citations

Involvement of p21ras in activation of extracellular signal-regulated kinase 2

1992 • 403 citations

Identification and purification of a polypeptide that binds to the c-fos serum response element.

1987 • 398 citations

Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity

1992 • 387 citations

Heterodimer formation of cJun and ATF-2 is responsible for induction of c-jun by the 243 amino acid adenovirus E1A protein.

1993 • 380 citations

Immunological Unresponsiveness Induced by Ultraviolet Radiation

1984 • 314 citations

c-fos Sequence Necessary for Basal Expression and Induction by Epidermal Growth Factor, 12-O-Tetradecanoyl Phorbol-13-Acetate and the Calcium Ionophore

1987 • 304 citations

Activation of the c-fos gene by UV and phorbol ester: different signal transduction pathways converge to the same enhancer element.

1988 • 271 citations

Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin.

1986 • 270 citations

UV-induced activation of AP-1 involves obligatory extranuclear steps including Raf-1 kinase.

1993 • 262 citations

Dimethyl sulfoxide prevents DNA nicking mediated by ionizing radiation or iron/hydrogen peroxide-generated hydroxyl radical.

1981 • 192 citations

DNA damage-induced gene expression: Signal transduction and relation to growth factor signaling

1992 • 187 citations

DNA excision-repair defect of xeroderma pigmentosum prevents removal of a class of oxygen free radical-induced base lesions.

1993 • 183 citations

Phorbol ester enhances human immunodeficiency virus-promoted gene expression and acts on a repeated 10-base-pair functional enhancer element.

1987 • 164 citations

UV-induced extracellular factor from human fibroblasts communicates the UV response to nonirradiated cells

1984 • 162 citations

ULTRAVIOLET‐RADIATION INDUCED c‐jun GENE TRANSCRIPTION: TWO AP‐1 LIKE BINDING SITES MEDIATE THE RESPONSE

1992 • 129 citations

UV irradiation-induced interleukin-1 and basic fibroblast growth factor synthesis and release mediate part of the UV response.

1993 • 126 citations

c-fos sequence necessary for basal expression and induction by epidermal growth factor, 12-O-tetradecanoyl phorbol-13-acetate and the calcium ionophore.

1987 • 126 citations

Jun is phosphorylated by several protein kinases at the same sites that are modified in serum-stimulated fibroblasts.

1992 • 123 citations

UV-induced transcription from the human immunodeficiency virus type 1 (HIV-1) long terminal repeat and UV-induced secretion of an extracellular factor that induces HIV-1 transcription in nonirradiated cells

1989 • 119 citations

In vitro activation of the HIV-1 enhancer in extracts from cells treated with a phorbol ester tumor promoter.

1987 • 100 citations

Adenovirus E1A negatively and positively modulates transcription of AP-1 dependent genes by dimer-specific regulation of the DNA binding and transactivation activities of Jun.

1993 • 98 citations

Induction of plasminogen activator by UV light in normal and xeroderma pigmentosum fibroblasts.

1981 • 96 citations

Global Trends in Total Ozone

1988 • 80 citations

Interleukin 1 induction of the c-jun promoter.

1993 • 73 citations

Induction of urokinase-type plasminogen activator by UV light in human fetal fibroblasts is mediated through a UV-induced secreted protein.

1987 • 69 citations

LONG‐WAVELENGTH UVA RADIATION INDUCES OXIDATIVE STRESS, CYTOSKELETAL DAMAGE and HEMOLYSIS*

1993 • 60 citations

Radiation-induced activation of transcription factors in mammalian cells

1990 • 54 citations

Indirect induction of erythroid differentiation in mouse Friend cells: evidence for two intracellular reactions involved in the differentiation.

1983 • 38 citations

A synthetic hapten for induction of thymine‐dimer‐specific antibodies

1984 • 20 citations

DEVELOPMENT OF AN in vitro SYSTEM FOR THE ANALYSIS OF ULTRAVIOLET RADIATION‐INDUCED SUPPRESSION OF NATURAL KILLER CELL ACTIVITY

1993 • 13 citations

Induced Effects of Genotoxic Agents in Eukaryotic Cells

1993 • 8 citations