Back to search

Landmark discrimination learning in the dog: effects of age, an antioxidant fortified food, and cognitive strategy

Data up to Jan 2025

Published2002
Citations141
References81

Total Citations Per Year

Abstract

References (81)

Aging: A Theory Based on Free Radical and Radiation Chemistry

1956 • 8,252 citations

Oxidants, antioxidants, and the degenerative diseases of aging.

1993 • 6,011 citations

The Free Radical Theory of Aging Matures

1998 • 3,846 citations

Protein Oxidation in Aging, Disease, and Oxidative Stress

1997 • 3,299 citations

Protein Oxidation and Aging

1992 • 2,687 citations

Oxidative damage and mitochondrial decay in aging.

1994 • 2,024 citations

Aging, energy, and oxidative stress in neurodegenerative diseases

1995 • 1,453 citations

Protein Oxidation

2000 • 935 citations

The pharmacology of the antioxidant lipoic acid

1997 • 817 citations

Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone.

1991 • 734 citations

Four-Hydroxynonenal, a Product of Lipid Peroxidation, is Increased in the Brain in Alzheimer’s Disease

1998 • 677 citations

Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: Partial reversal by feeding acetyl- <scp>l</scp> -carnitine and/or R -α-lipoic acid

2002 • 510 citations

Increased Nuclear DNA Oxidation in the Brain in Alzheimer's Disease

1998 • 467 citations

Long-Term Dietary Strawberry, Spinach, or Vitamin E Supplementation Retards the Onset of Age-Related Neuronal Signal-Transduction and Cognitive Behavioral Deficits

1998 • 434 citations

Dissociation of spatial discrimination deficits following frontal and parietal lesions in monkeys.

1973 • 425 citations

Decreases in Regional Cerebral Blood Flow with Normal Aging

1991 • 400 citations

Automated assay of oxygen radical absorbance capacity with the COBAS FARA II

1995 • 392 citations

Micronutrients prevent cancer and delay aging

1998 • 365 citations

Dissociation of the Medial Prefrontal, Posterior Parietal, and Posterior Temporal Cortex for Spatial Navigation and Recognition Memory in the Rat

1994 • 364 citations

Severity of memory impairment in monkeys as a function of locus and extent of damage within the medial temporal lobe memory system

1994 • 360 citations

The role of oxidative stress in the toxicity induced by amyloid β-peptide in Alzheimer’s disease

2000 • 358 citations

Antioxidant-rich diets improve cerebellar physiology and motor learning in aged rats

2000 • 306 citations

(R)‐α‐Lipoic acid‐supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate

1999 • 297 citations

Oxidants Are a Major Contributor to Aginga

1992 • 296 citations

Aging in the Rhesus Monkey: Debilitating Effects on Short-term Memory

1978 • 284 citations

Age-associated mitochondrial oxidative decay: Improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl- <scp>l</scp> - carnitine and/or R -α-lipoic acid

2002 • 274 citations

Patterns of cognitive decline in aged rhesus monkeys

1997 • 273 citations

Evidence for task-dependent memory dysfunction in the aged monkey

1989 • 269 citations

Acetyl- <scp>l</scp> -carnitine fed to old rats partially restores mitochondrial function and ambulatory activity

1998 • 264 citations

A comparison of egocentric and allocentric spatial memory in a patient with selective hippocampal damage

2000 • 260 citations

Aged monkeys exhibit behavioral deficits indicative of widespread cerebral dysfunction

1991 • 258 citations

Functional Neurobiology of Aging

2001 • 251 citations

Neurobehavioral aspects of antioxidants in aging

2000 • 235 citations

Cognitive functions and aging in the dog: Acquisition of nonspatial visual tasks.

1994 • 224 citations

β-Amyloid Accumulation Correlates with Cognitive Dysfunction in the Aged Canine

1996 • 217 citations

Cognitive functions and aging in the dog: Acquisition of nonspatial visual tasks.

1994 • 196 citations

Evidence of an oxidative challenge in the Alzheimer's brain

1994 • 194 citations

Oxidative damage increases with age in a canine model of human brain aging

2002 • 191 citations

Chronic antioxidant treatment improves the cognitive performance of aged rats

1995 • 186 citations

Aging in the Rhesus Monkey: Effects on Visual Discrimination Learning and Reversal Learning

1979 • 181 citations

Effects of aging on visual recognition memory in the rhesus monkey

1988 • 180 citations

Landmark stability is a prerequisite for spatial but not discrimination learning

1993 • 179 citations

Alpha-lipoic acid as a new treatment option for Azheimer type dementia

2001 • 179 citations

Executive system dysfunction in the aged monkey: Spatial and object reversal learning

1995 • 171 citations

Visual-discrimination learning ability and β-amyloid accumulation in the dog

1998 • 170 citations

The canine as a model of human cognitive aging: Recent developments

2000 • 158 citations

Dietary enrichment counteracts age-associated cognitive dysfunction in canines

2002 • 146 citations

Spatial learning and memory as a function of age in the dog.

1995 • 131 citations

Spatial learning and memory as a function of age in the dog.

1995 • 129 citations

Use of a delayed non-matching to position task to model age-dependent cognitive decline in the dog

2000 • 110 citations

Visual discrimination and reversal learning in the aged monkey (Macaca mulatta).

1990 • 110 citations

Impaired spatial information processing in aged monkeys with preserved recognition memory

1997 • 110 citations

Memory Functioning in Dementia

1992 • 110 citations

Oxidative stress protection and vulnerability in aging: putative nutritional implications for intervention

2000 • 107 citations

Visuospatial impairments in aged canines (Canis familiaris): The role of cognitive-behavioral flexibility.

2002 • 104 citations

Lateral ventricle injection of the protein synthesis inhibitor anisomycin impairs long-term memory in a spatial memory task

1998 • 100 citations

Visual discrimination and reversal learning in the aged monkey (Macaca mulatta).

1990 • 97 citations

Impairments in acquisition and reversals of two-choice discriminations by aged rhesus monkeys

1999 • 93 citations

Landmark Discrimination Learning in the Dog

1999 • 90 citations

Equivalence of parieto-preoccipital subareas for visuospatial ability in monkeys

1982 • 84 citations

The fractionation of remote memory

1996 • 83 citations

Age-related changes in LTP and antioxidant defenses are reversed by an α-lipoic acid-enriched diet

1999 • 81 citations

Effects of object preferences and aversions on discrimination learning in monkeys with frontal lesions.

1961 • 80 citations

Oxidative base damage in RNA detected by reverse transcriptase

1995 • 72 citations

Chronic antioxidant supplementation attenuates nuclear factor-κB activation and preserves endothelial function in hypercholesterolemic pigs

2002 • 70 citations

Remote memory: Recalling autobiographical and public events from across the lifespan.

1992 • 62 citations

Spatial encoding of hidden objects in dogs (Canis familiaris).

2000 • 60 citations

Alpha-lipoic acid modulates NF-κB activity in human monocytic cells by direct interaction with DNA

2002 • 60 citations

Development of a protocol for studying object recognition memory in the dog

2000 • 59 citations

Effects of ageing on allocentric and egocentric spatial strategies in the Wistar rat

2001 • 50 citations

Visuospatial Dysgnosia

1979 • 45 citations

Behavioral changes in aged rhesus monkeys

1993 • 40 citations

Extraction of α-Tocopherol from Serum Prior to Reversed-Phase Liquid Chromatography

1998 • 33 citations

α‐tocopherol concentrations of the nervous system and selected tissues of adult dogs fed three levels of vitamin E

1993 • 30 citations

Object discrimination learning in aged Japanese monkeys.

2001 • 28 citations

The longitudinal assessment of recognition memory in aged rhesus monkeys

1993 • 21 citations

Age-related working memory deficits in the allocentric place discrimination task: possible involvement in cholinergic dysfunction

1999 • 18 citations

Color Vision, Object Recognition, and Spatial Localization in Aging and Alzheimer's Disease

2001 • 15 citations

In search of molecular memory: experience-driven protein synthesis

2000 • 12 citations

Landmark discrimination in the rat: A measure of allocentric spatial ability.

1994 • 5 citations

Landmark discrimination in the rat: A measure of allocentric spatial ability.

1994 • 5 citations

Cited By (0)

Loading...