Uroporphyrinogen decarboxylase: a splice site mutation causes the deletion of exon 6 in multiple families with porphyria cutanea tarda.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Measurement of protein using bicinchoninic acid

1985 • 17,516 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

1988 • 4,259 citations

SPLICING OF MESSENGER RNA PRECURSORS

1986 • 1,233 citations

Hemoglobin: Molecular, Genetic and Clinical Aspects.

1986 • 1,005 citations

Splicing of Messenger RNA Precursors

1987 • 919 citations

Splicing of Messenger RNA Precursors

1984 • 874 citations

Sequence requirements for splicing of higher eukaryotic nuclear pre-mRNA

1986 • 389 citations

An inherited enzymatic defect in porphyria cutanea tarda: decreased uroporphyrinogen decarboxylase activity.

1976 • 283 citations

Scanning from an independently specified branch point defines the 3′ splice site of mammalian introns

1989 • 267 citations

The role of the mammalian branchpoint sequence in pre-mRNA splicing.

1988 • 215 citations

UACUAAC is the preferred branch site for mammalian mRNA splicing.

1989 • 180 citations

Identification of a mutation that causes exon skipping during collagen pre-mRNA splicing in an Ehlers-Danlos syndrome variant.

1988 • 146 citations

Macrocyclic intermediates in the biosynthesis of porphyrins

1976 • 139 citations

Purification and properties of uroporphyrinogen decarboxylase from human erythrocytes. A single enzyme catalyzing the four sequential decarboxylations of uroporphyrinogens I and III.

1983 • 138 citations

Molecular cloning and nucleotide sequence of a complete human uroporphyrinogen decarboxylase cDNA.

1986 • 107 citations

Uroporphyrinogen Decarboxylase Structural Mutant (Gly281→Glu) in a Case of Porphyria

1986 • 95 citations

Branch point selection in alternative splicing of tropomyosin pre-mRNAs

1989 • 89 citations

Single base mutation in the pro alpha 2(I) collagen gene that causes efficient splicing of RNA from exon 27 to exon 29 and synthesis of a shortened but in-frame pro alpha 2(I) chain.

1988 • 83 citations

Uroporphyrinogen decarboxylase. Purification, properties, and inhibition by polychlorinated biphenyl isomers.

1983 • 81 citations

Chicken triosephosphate isomerase complements an Escherichia coli deficiency.

1985 • 76 citations

Purification and characterization of bovine hepatic uroporphyrinogen decarboxylase

1983 • 75 citations

Structure of the gene for human uroporphyrinogen decarboxylase

1987 • 67 citations

Investigations of rat liver uroporphyrinogen decarboxylase. Comparisons of porphyrinogens I and III as substrates and the inhibition by porphyrins

1981 • 64 citations

A point mutation in the coding region of uroporphyrinogen decarboxylase associated with familial porphyria cutanea tarda

1989 • 58 citations

Hepatoerythropoietic Porphyria: Clinical, Biochemical, and Enzymatic Studies in a Three-Generation Family Lineage

1987 • 58 citations

Purification of uroporphyrinogen decarboxylase from human erythrocytes. Immunochemical evidence for a single protein with decarboxylase activity in human erythrocytes and liver

1983 • 54 citations

In vitro splicing pathways of pre-mRNAs containing multiple intervening sequences?

1987 • 39 citations

Prevalence of the 281 (Gly→Glu) mutation in hepatoerythropoietic porphyria and porphyria cutanea tarda

1988 • 30 citations

Stereochemical and mechanistic studies on the decarboxylation of uroporphyrinogen III in haem biosynthesis

1979 • 30 citations

Uroporphyrinogen decarboxylase. A method for measuring enzyme activity.

1982 • 28 citations

In Vitro Splicing Pathways of Pre-mRNAs Containing Multiple Intervening Sequences

1987 • 24 citations

Assays of the heme biosynthetic enzymes. Preface.

1982 • 11 citations

Steady-state levels of uroporphyrinogen decarboxylase mRNA in lymphoblastoid cell lines from patients with familial porphyria cutanea tarda and their relatives.

1988 • 9 citations

A point mutation in the coding region of uroporphyrinogen decarboxylase associated with familial porphyria cutanea tarda

1989 • 6 citations