Nervous tissue as an immune compartment: the dialect of the immune response in the CNS

Van Damme A.

1986 • 3,477 citations

Prevention of experimental autoimmune encephalomyelitis by antibodies against α4βl integrin

1992 • 1,711 citations

The T Lymphocyte in Experimental Allergic Encephalomyelitis

1990 • 1,005 citations

Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma.

1993 • 837 citations

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

1984 • 773 citations

Cervical lymphatics, the blood-brain barrier and the immunoreactivity of the brain: a new view

1992 • 653 citations

Antigen presentation and tumor cytotoxicity by interferon‐γ‐treated microglial cells

1987 • 648 citations

Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery.

1992 • 627 citations

Intercellular adhesion molecule-1 (ICAM-1) in cellular immune reactions in the human central nervous system.

1990 • 388 citations

Interleukins-1 and -6 Stimulate the Release of Corticotropin-Releasing Hormone-41 from Rat Hypothalamusin Vitrovia the Eicosanoid Cyclooxygenase Pathway*

1991 • 331 citations

Cytokines as modulators of the hypothalamus-pituitary-adrenal axis

1991 • 289 citations

Stimulation of oligodendroglial proliferation and maturation by interleukin-2

1986 • 251 citations

Production of hemopoietic colony-stimulating factors by astrocytes.

1990 • 237 citations

Homing to central nervous system vasculature by antigen-specific lymphocytes. I. Localization of 14C-labeled cells during acute, chronic, and relapsing experimental allergic encephalomyelitis.

1990 • 234 citations

Product ion of the cytokines interleukin 1 and 6 by murine brain microvessel endothelium and smooth muscle pericytes

1993 • 204 citations

Microglial cells are a component of the perivascular glia limitans

1991 • 203 citations

TNFα induces IL-6 production by astrocytes but not by microglia

1992 • 185 citations

Upregulation and coexpression of adhesion molecules correlate with relapsing autoimmune demyelination in the central nervous system.

1990 • 173 citations

Blood-Brain Barrier Damage in Patients with Bacterial Meningitis: Association with Tumor Necrosis Factor- but not Interleukin-I

1992 • 157 citations

Adhesion molecules on murine brain microvascular endothelial cells: expression and regulation of ICAM-1 and Lgp 55

1992 • 156 citations

Interleukin 6 production in the central nervous system during experimental autoimmune encephalomyelitis

1990 • 149 citations

Ultrastructural Location of Major Histocompatibility Complex (MHC) Class II Positive Perivascular Cells in Histologically Normal Human Brain

1992 • 148 citations

The reaction of pericytes of the central nervous system to exogenous protein.

1972 • 137 citations

Multiple sclerosis: a pivotal role for the T cell in lesion development

1991 • 118 citations

Antigen presentation in brain: MHC induction on brain endothelium and astrocytes compared.

1987 • 115 citations

Is interleukin 2 a neuromodulator in the brain?

1991 • 111 citations

Transforming growth factor-beta 1 (TGF-β1) expression and regulation in rat cortical astrocytes

1992 • 106 citations

Neutral Amino Acid Transport Properties of Cerebral Endothelial Cells in Vitro

1983 • 82 citations

Central corticotropin-releasing hormone activates the sympathetic nervous system and reduces immune function: increased responsivity of the aged rat.

1992 • 75 citations

Preliminary studies of cytokine-induced functional effects on the visual pathways in the rabbit

1989 • 72 citations

Production of Peptide Hormones and Neurotransmitters by the Immune System

1992 • 67 citations

A lymphocyte homing receptor (L-selectin) mediates the in vitro attachment of lymphocytes to myelinated tracts of the central nervous system.

1991 • 63 citations

H-CAM expression in the human nervous system: Evidence for a role in diverse glial interactions

1992 • 63 citations

Transforming growth factor-β1 differentially regulates proliferation and MHC class-II antigen expression in forebrain and brainstem astrocyte primary cultures

1992 • 60 citations

Evidence for antigen presentation in situ by endothelial cells and astrocytes

1985 • 50 citations

Human brain microvascular DR‐antigen

1989 • 48 citations

Antigen presentation by brain microvessel smooth muscle and endothelium

1990 • 47 citations

Induction of Ia molecules on brain endothelium is related to susceptibility to experimental allergic encephalomyelitis

1989 • 46 citations

Central nervous system endothelial cell-polymorphonuclear cell interactions during autoimmune demyelination.

1991 • 41 citations

Cerebral vascular endothelial cells are effective targets for in vitro lysis by encephalitogenic T lymphocytes.

1991 • 40 citations

Immunomodulatory Action of Somatostatin

1987 • 38 citations

Central corticotropin-releasing hormone activates the sympathetic nervous system and reduces immune function: increased responsivity of the aged rat

1992 • 37 citations

Cytokines up-regulate Ia expression in organotypic cultures of central nervous system tissue

1989 • 36 citations

The inhibitory effect of tumor necrosis factor and interleukin-1 on Ia induction by interferon-γ on endothelial cells from murine central nervous system microvessels

1990 • 36 citations

The central effect of methionine-enkephalin on NK cell activity

1992 • 31 citations

Brain microvascular smooth muscle and endothelial cells produce granulocyte macrophage colony-stimulating factor and support colony formation of granulocyte-macrophage-like cells.

1992 • 31 citations

Catecholamines stimulate the IFN-gamma-induced class II MHC expression on bovine brain capillary endothelial cells.

1991 • 26 citations

Immune cell traffic control and the central nervous system

1992 • 24 citations

Adhesion of splenocytes to brain microvascular endothelium in the BALB/c and SJL/j mouse systems

1991 • 17 citations

The inflammatory cytokine IL-22 promotes murine gliomas via proliferation

2017 • 9 citations

Neurotransmitter induction of glial cell cytokines

1993 • 3 citations

Neuropeptides modulate interleukin production in murine schistosomiasis

1993 • 1 citations

Effect of neuropeptides on human monocyte/macrophage functions in vitro

1993 • 1 citations

Binding and pharmacological evidence for a special subtype of delta opioid receptor on human and invertebrate immune cells

1993 • 1 citations

Neuroimmune interaction of TGFβ1 and TGFβ2

1993 • 1 citations