Sequestration of doxorubicin in vesicles in a multidrug-resistant cell line (LZ-100)

DNA Damage Produced by Ionizing Radiation in Mammalian Cells: Identities, Mechanisms of Formation, and Reparability

1988 • 1,434 citations

Mechanism of multidrug resistance

1988 • 630 citations

The cell biology of multiple drug resistance

1987 • 340 citations

Separation of drug transport and chloride channel functions of the human multidrug resistance P-glycoprotein

1992 • 328 citations

Glutathione S-transferases and drug resistance

1991 • 299 citations

Multifactorial drug resistance in an adriamycin-resistant human small cell lung carcinoma cell line.

1987 • 266 citations

Selfassociation of daunomycin

1982 • 259 citations

Differential formation of hydroxyl radicals by adriamycin in sensitive and resistant MCF-7 human breast tumor cells: implications for the mechanism of action

1987 • 214 citations

Mechanisms of Multidrug Resistance in Cancer Treatment

1992 • 208 citations

P-glycoproteins in pathology: The multidrug resistance gene family in humans

1990 • 173 citations

Subcellular distribution of daunorubicin in P-glycoprotein-positive and -negative drug-resistant cell lines using laser-assisted confocal microscopy.

1991 • 160 citations

Membrane vesicle formation due to acquired mitoxantrone resistance in human gastric carcinoma cell line EPG85-257.

1990 • 148 citations

Intracellular distribution and pharmacokinetics of daunorubicin in anthracycline-sensitive and -resistant HL-60 cells.

1989 • 132 citations

Genetic basis of multidrug resistance of tumor cells

1990 • 124 citations

Quantitative Determination of Factors Contributing to Doxorubicin Resistance in Multidrug-Resistant Cells

1989 • 102 citations

Glutathione S-transferases and drug resistance

1991 • 98 citations

Drug transport mechanisms in HL60 cells isolated for resistance to adriamycin: evidence for nuclear drug accumulation and redistribution in resistant cells.

1992 • 94 citations

Increase in Nonspecific Adsorptive Endocytosis in Anthracycline-and Vinca Alkaloid-Resistant Ehrlich Ascites Tumor Cell Lines2

1987 • 87 citations

Chloroquine enhancement of anticancer drug cytotoxicity in multiple drug resistant human leukemic cells

1986 • 85 citations

Laser scanning and confocal microscopy of daunorubicin, doxorubicin, and rhodamine 123 in multidrug-resistant cells

1991 • 79 citations

Increased plasma membrane traffic in daunorubicin resistant P388 leukaemic cells. Effect of daunorubicin and verapamil

1987 • 79 citations

Self‐association of daunorubicin

1974 • 75 citations

Cross-resistance to rhodamine 123 in Adriamycin- and daunorubicin-resistant Friend leukemia cell variants.

1984 • 74 citations

Mechanisms of multidrug resistance in human tumor cells. The roles of P-glycoprotein, DNA topoisomerase II, and other factors

1990 • 70 citations

High-level, unstable adriamycin resistance in a Chinese hamster mutant cell line with double minute chromosomes.

1984 • 67 citations

The effect of lysosomotropic agents and secretory inhibitors on anthracycline retention and activity in multiple drug-resistant cells.

1988 • 66 citations

Enhanced efflux of [3H]vinblastine from Chinese hamster ovary cells transfected with a full-length complementary DNA clone for the mdr1 gene.

1989 • 64 citations

What's New in Cytostatic Drug Resistance and Pathology

1991 • 48 citations

Secretion of lysosomal enzymes by drug-sensitive and multiple drug-resistant cells.

1991 • 46 citations

Cytofluorescence localization of adriamycin in resistant colon cancer cells

1984 • 44 citations

Why haven't we cured multidrug resistant tumors?

1992 • 37 citations

Dot-blot hybridization: quantitative analysis with direct beta counting.

1991 • 31 citations

Mechanism of multidrug resistance in human tumour cell lines and complete reversion of cellular resistance

1992 • 30 citations

Radioprotection of membranes

1988 • 25 citations

Multidrug Resistance

1991 • 19 citations

Characterization of adriamycin-resistant and radiation-sensitive Chinese hamster cell lines

1992 • 19 citations

Keynote address: Multidrug resistance: A pleiotropic response to cytotoxic drugs

1991 • 18 citations

Interaction between Radiation and Drug Damage in Mammalian Cells: IV. Radiation Response of Adriamycin-Resistant V79 Cells

1989 • 15 citations

Transfer of adriamycin resistance by fusion of Mr 170,000 P-glycoprotein to the plasma membrane of sensitive cells.

1990 • 14 citations

Glutathione 5-transferase and P-glycoprotein in multidrug resistant chinese hamster cells

1990 • 14 citations

The influence of pH on the interaction of lipophilic anthracyclines with bovine serum albumin

1992 • 13 citations

Interaction between Radiation and Drug Damage in Mammalian Cells. V. DNA Damage and Repair Induced in LZ Cells by Adriamycin and/or Radiation

1991 • 11 citations

An enhanced ability for transforming adriamycin into a noncytotoxic form in a multidrug-resistant cell line (LZ-8)

1992 • 10 citations

Electrophysiological effects of basolateral [Na+] in Necturus gallbladder epithelium.

1992 • 8 citations

Interaction between Radiation and Drug Damage in Mammalian Cells. VI. Radiation and Doxorubicin Age-Response Function of Doxorubicin-Sensitive and -Resistant Chinese Hamster Cells

1992 • 3 citations

Surface heterogeneity of tumor cells and changes upon ionizing radiation.

1989 • 3 citations