A genome-wide scan points to a susceptibility locus for bipolar disorder on chromosome 12

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

1995 • 5,291 citations

PedCheck: A Program for Identification of Genotype Incompatibilities in Linkage Analysis

1998 • 2,089 citations

Faster sequential genetic linkage computations.

1993 • 1,378 citations

Handbook of Human Genetic Linkage.

1996 • 878 citations

Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease

1999 • 699 citations

Avoiding Recomputation in Linkage Analysis

1994 • 679 citations

Handbook of human genetic linkage

1995 • 591 citations

Genetics of bipolar disorder

1999 • 529 citations

The VITESSE algorithm for rapid exact multilocus linkage analysis via genotype set–recoding and fuzzy inheritance

1995 • 514 citations

A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: II. Suicidal behavior

2003 • 417 citations

A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2

1999 • 399 citations

Chromosome 18 DNA markers and manic-depressive illness: evidence for a susceptibility gene.

1994 • 378 citations

Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect.

1995 • 347 citations

SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene provide evidence for association with major depression

2004 • 323 citations

A possible vulnerability locus for bipolar affective disorder on chromosome 21q22.3

1994 • 320 citations

Replication of Linkage Studies of Complex Traits: An Examination of Variation in Location Estimates

1999 • 282 citations

A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: I. Affective disorders

2003 • 272 citations

A locus for bipolar affective disorder on chromosome 4p

1996 • 272 citations

Polymorphisms at the G72/G30 Gene Locus, on 13q33, Are Associated with Bipolar Disorder in Two Independent Pedigree Series*

2003 • 270 citations

Genetic mapping using haplotype, association and linkage methods suggests a locus for severe bipolar disorder (BPI) at 18q22-q23

1996 • 260 citations

Affected-sib-pair interval mapping and exclusion for complex genetic traits: Sampling considerations

1996 • 225 citations

Genome-wide search for linkage of bipolar affective disorders in a very large pedigree derived from a homogeneous population in Quebec points to a locus of major effect on chromosome 12q23-q24

1999 • 221 citations

High-resolution genetic mapping of complex traits.

1995 • 220 citations

Initial genome scan of the NIMH genetics initiative bipolar pedigrees: Chromosomes 1, 6, 8, 10, and 12

1997 • 218 citations

Predisposition Locus for Major Depression at Chromosome 12q22-12q23.2

2003 • 196 citations

Genetic Approaches to Mental Disorders

1995 • 173 citations

Chromosome 18 DNA markers and manic-depressive illness : evidence for a susceptibility gene

1994 • 169 citations

Initial genomic scan of the NIMH genetics initiative bipolar pedigrees: Chromosomes 3, 5, 15, 16, 17, and 22

1997 • 165 citations

Genome scan of pedigrees multiply affected with bipolar disorder provides further support for the presence of a susceptibility locus on chromosome 12q23-q24, and suggests the presence of additional loci on 1p and 1q

2003 • 152 citations

Evidence of a predisposing locus to bipolar disorder on Xq24-q27.1 in an extended Finnish pedigree.

1995 • 142 citations

True and False Positive Peaks in Genomewide Scans: Applications of Length-Biased Sampling to Linkage Mapping

1997 • 140 citations

Initial Genome Scan of the NIMH Genetics Initiative Bipolar Pedigrees: Chromosomes 4, 7, 9, 18, 19, 20, and 21q

1997 • 133 citations

Familial Cosegregation of Major Affective Disorder and Darier's Disease (Keratosis Follicularis)

1994 • 133 citations

A genome-wide scan shows significant linkage between bipolar disorder and chromosome 12q24.3 and suggestive linkage to chromosomes 1p22–21, 4p16, 6q14–22, 10q26 and 16p13.3

2002 • 130 citations

Evaluation of linkage of bipolar affective disorder to chromosome 18 in a sample of 57 German families

1999 • 129 citations

Affected-sib-pair analyses reveal support of prior evidence for a susceptibility locus for bipolar disorder, on 21q.

1996 • 124 citations

Evidence for a putative bipolar disorder locus on 2p13–16 and other potential loci on 4q31, 7q34, 8q13, 9q31, 10q21–24, 13q32, 14q21 and 17q11–12

2003 • 124 citations

Significant linkage between bipolar affective disorder and chromosome 12q24

1998 • 119 citations

Linkage studies of bipolar disorder in the region of the Darier's disease gene on chromosome 12q23‐24.1

1995 • 107 citations

Initial genome screen for bipolar disorder in the NIMH genetics initiative pedigrees: Chromosomes 2, 11, 13, 14, and X

1997 • 104 citations

Linkage of Bipolar Affective Disorder to Chromosome 18 Markers in a New Pedigree Series

1997 • 100 citations

Two-Locus Admixture Linkage Analysis of Bipolar and Unipolar Affective Disorder Supports the Presence of Susceptibility Loci on Chromosomes 11p15 and 21q22

1997 • 93 citations

Further Evidence for the Increased Power of LOD Scores Compared with Nonparametric Methods

1999 • 88 citations

Evidence of susceptibility loci on 4q32 and 16p12 for bipolar disorder

2003 • 83 citations

Support for the possible locus on chromosome 4p16 for bipolar affective disorder

1998 • 78 citations

A study of chromosome 4p markers and dopamine D5 receptor gene in schizophrenia and bipolar disorder

1998 • 70 citations

Inter- and intrafamilial heterogeneity: effective sampling strategies and comparison of analysis methods.

1992 • 66 citations

Assessing the Feasibility of Linkage Disequilibrium Methods for Mapping Complex Traits: An Initial Screen for Bipolar Disorder Loci on Chromosome 18

1999 • 65 citations

Genetic association between alleles of pancreatic phospholipase A2 gene and bipolar affective disorder

1995 • 58 citations

Anticipation and repeat expansion in bipolar disorder

2003 • 57 citations

Further evidence for a bipolar risk gene on chromosome 12q24 suggested by investigation of haplotype sharing and allelic association in patients from the Faroe Islands

2001 • 53 citations

Exclusion of the Darier's disease gene, ATP2A2, as a common susceptibility gene for bipolar disorder

2000 • 50 citations

Linkage Analysis of a Complex Pedigree with Severe Bipolar Disorder, Using a Markov Chain Monte Carlo Method

2001 • 50 citations

Population isolates: their special value for locating genes for bipolar disorder

2001 • 48 citations

Genome wide scan using homozygosity mapping and linkage analyses of a single pedigree with affective disorder suggests oligogenic inheritance

2003 • 47 citations

Hyperekplexia: abnormal startle response due to glycine receptor mutations

1997 • 40 citations

An approach to high-throughput genotyping.

1996 • 40 citations

Fine mapping supports previous linkage evidence for a bipolar disorder susceptibility locus on 13q32

2001 • 35 citations

Possible evidence for a common risk locus for bipolar affective disorder and schizophrenia on chromosome 4p16 in patients from the Faroe Islands

2003 • 32 citations

Linkage of a bipolar disorder susceptibility locus to human chromosome 13q32 in a new pedigree series

2003 • 31 citations

Association study of bipolar disorder at the phospholipase A2 gene (PLA2A) in the Darierʼs disease (DAR) region of chromosome 12q23-q24.1

1996 • 26 citations

Regional inference with averagedPvalues increases the power to detect linkage

1999 • 20 citations

Improvement of the power to detect complex disease genes by regional inference procedures

1997 • 19 citations

Refined Genetic Mapping of the Darier Locus to a <1-cM Region of Chromosome 12q24.1, and Construction of a Complete, High-Resolution P1 Artificial Chromosome/Bacterial Artificial Chromosome Contig of the Critical Region

1998 • 15 citations

Genetic heterogeneity in a very large bipolar affective disorder pedigree from Quebec

2003 • 6 citations

Use of Weighted p‐Values in Regional Inference Procedures

2001 • 3 citations