Linkage Analysis of a Complex Pedigree with Severe Bipolar Disorder, Using a Markov Chain Monte Carlo Method

Easy calculations of lod scores and genetic risks on small computers.

1984 • 1,526 citations

Construction of multilocus genetic linkage maps in humans.

1987 • 1,461 citations

Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics.

1996 • 1,201 citations

Complete multipoint sib-pair analysis of qualitative and quantitative traits.

1995 • 929 citations

Bipolar affective disorders linked to DNA markers on chromosome 11

1987 • 826 citations

The affected-pedigree-member method of linkage analysis.

1988 • 493 citations

A Class of Tests for Linkage Using Affected Pedigree Members

1994 • 346 citations

Allele frequency estimation from data on relatives.

1991 • 271 citations

Genetic mapping using haplotype, association and linkage methods suggests a locus for severe bipolar disorder (BPI) at 18q22-q23

1996 • 260 citations

A complete genome screen for genes predisposing to severe bipolar disorder in two Costa Rican pedigrees

1996 • 175 citations

A genome-wide search for chromosomal loci linked to bipolar affective disorder in the Old Order Amish

1996 • 173 citations

An approach to investigating linkage for bipolar disorder using large Costa Rican pedigrees

1996 • 44 citations