Replication of Linkage Studies of Complex Traits: An Examination of Variation in Location Estimates

Numerical Recipes, The Art of Scientific Computing

1987 • 10,372 citations

The Advanced Theory of Statistics.

1978 • 6,960 citations

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

1995 • 5,291 citations

Numerical Recipes: The Art of Scientific Computing

1987 • 4,758 citations

Parametric and nonparametric linkage analysis: a unified multipoint approach.

1996 • 2,905 citations

The Advanced Theory of Statistics

1963 • 1,885 citations

Complete multipoint sib-pair analysis of qualitative and quantitative traits.

1995 • 929 citations

A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22

1996 • 638 citations

Positional cloning moves from perditional to traditional

1995 • 603 citations

Detecting marker-QTL linkage and estimating QTL gene effect and map location using a saturated genetic map.

1993 • 493 citations

A potential vulnerability locus for schizophrenia on chromosome 6p24–22: evidence for genetic heterogeneity

1995 • 465 citations

A simple method to calculate resolving power and confidence interval of QTL map location.

1997 • 425 citations

Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan

1997 • 418 citations

Linkage strategies for genetically complex traits. III. The effect of marker polymorphism on analysis of affected relative pairs.

1990 • 398 citations

An international two–stage genome–wide search for schizophrenia susceptibility genes

1995 • 385 citations

A search for type 1 diabetes susceptibility genes in families from the United Kingdom

1998 • 329 citations

Genomewide Scan of Multiple Sclerosis in Finnish Multiplex Families

1997 • 308 citations

Testing for heterogeneity of recombination fraction values in Human Genetics

1963 • 303 citations

Eye Tracking Dysfunction and Schizophrenia: A Critical Perspective

1993 • 287 citations

Evaluation of a susceptibility gene for schizophrenia on chromosome 6p by multipoint affected sib–pair linkage analysis

1995 • 279 citations

Evidence that a locus for familial psoriasis maps to chromosome 4q

1996 • 226 citations

Eye tracking dysfunction is a putative phenotypic susceptibility marker of schizophrenia and maps to a locus on chromosome 6p in families with multiple occurrence of the disease

1996 • 185 citations

Adequacy of single‐locus approximations for linkage analyses of oligogenic traits

1992 • 107 citations

Susceptibility to Insulin-Dependent Diabetes Mellitus Maps to a Locus (IDDM11) on Human Chromosome 14q24.3–q31

1996 • 99 citations

Further Evidence for the Increased Power of LOD Scores Compared with Nonparametric Methods

1999 • 88 citations

Linkage analysis of putative schizophrenia gene candidate regions on chromosomes 3p, 5q, 6p, 8p, 20p and 22q in a population-based sampled Finnish family set

1998 • 80 citations

Use of a Quantitative Trait to Map a Locus Associated with Severity of Positive Symptoms in Familial Schizophrenia to Chromosome 6p

1997 • 71 citations

6p24-22 region and major psychoses in the Eastern Quebec population. Le Groupe IREP.

1997 • 70 citations

Linkage analysis under “random” and “genetic” reduced penetrance

1989 • 70 citations

Cutting a Gordian knot in the linkage analysis of complex human traits.

1990 • 68 citations

6p24–22 Region and Major Psychoses in the Eastern Quebec Population

1997 • 63 citations

Surgical Emphysema as a Complication of Anaesthesia

1955 • 9 citations

Non-parametric analysis of chromosome 6p24–22 marker data and schizophrenia in southern African Bantu-speaking families

1997 • 7 citations