Pycnogenol inhibits tumor necrosis factor- ? -induced nuclear factor kappa B activation and adhesion molecule expression in human vascular endothelial cells

Structure, Regulation and Function of NF-kappaB

1994 • 2,110 citations

Antioxidant and redox regulation of gene transcription

1996 • 1,999 citations

Transcriptional regulation of endothelial cell adhesion molecules: NF‐κB and cytokine‐inducible enhancers

1995 • 1,715 citations

Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells.

1993 • 1,079 citations

Intercellular Adhesion Molecule-1 (ICAM-1) in the Pathogenesis of asthma

1990 • 916 citations

Redox Regulation of NF-kappa B Activation

1997 • 852 citations

Antioxidant activity and biologic properties of a procyanidin-rich extract from pine (pinus maritima) bark, pycnogenol

1999 • 643 citations

Expression of intercellular adhesion molecule-1 in atherosclerotic plaques.

1992 • 585 citations

Overexpression of Manganese Superoxide Dismutase Suppresses Tumor Necrosis Factor-induced Apoptosis and Activation of Nuclear Transcription Factor-κB and Activated Protein-1

1998 • 580 citations

Endothelial nuclear factor-kappa B and the initiation of the atherosclerotic lesion.

1993 • 525 citations

Reactive Oxygen Species Mediate Cytokine Activation of c-Jun NH2-terminal Kinases

1996 • 491 citations

Skeletal muscle myocytes undergo protein loss and reactive oxygen-mediated NF-κB activation in response to tumor necrosis factor α

1998 • 486 citations

Functional analysis of the human vascular cell adhesion molecule 1 promoter.

1992 • 442 citations

Antioxidants inhibit monocyte adhesion by suppressing nuclear factor-kappa B mobilization and induction of vascular cell adhesion molecule-1 in endothelial cells stimulated to generate radicals.

1994 • 349 citations

E-selectin expression in human endothelial cells by TNF-α-induced oxidant generation and NF-κB activation

1998 • 171 citations

Differential regulation of vascular cell adhesion molecule 1 gene expression by specific NF-kappa B subunits in endothelial and epithelial cells.

1993 • 170 citations

Modulation of transcription factor NFχB activity by intracellular glutathione levels and by variations of the extracellular cysteine supply

1995 • 168 citations

A set of inducible genes expressed by activated human monocytic and endothelial cells contain kappa B-like sites that specifically bind c-Rel-p65 heterodimers.

1994 • 155 citations

Vascular cell adhesion molecule 1: contrasting transcriptional control mechanisms in muscle and endothelium.

1993 • 90 citations

Effects of anti-nuclear factor kappa B reagents in blocking adhesion of human cancer cells to vascular endothelial cells.

1995 • 78 citations

Pycnogenol Inhibits Macrophage Oxidative Burst, Lipoprotein Oxidation, and Hydroxyl Radical-Induced DNA Damage

1998 • 62 citations

Pycnogenol enhances endothelial cell antioxidant defenses

1997 • 62 citations

Proteasome inhibitors block VCAM‐1 and ICAM‐1 gene expression in endothelial cells without affecting nuclear translocation of nuclear factor‐ϰB

1996 • 46 citations

Pycnogenol protects vascular endothelial cells from t-butyl hydroperoxide induced oxidant injury.

1994 • 44 citations

Activation of Transcriptionally Active Nuclear Factor-κB by Tumor Necrosis Factor-α and Its Inhibition by Antioxidants in Rat Thyroid FRTL-5 Cells¹

1998 • 42 citations

Endothelial cell associated platelet-activating factor (PAF), a costimulatory intermediate in TNF-alpha-induced H2O2 release by adherent neutrophil leukocytes.

1995 • 41 citations

Ginkgo biloba inhibits hydrogen peroxide–induced activation of nuclear factor kappa B in vascular endothelial cells

1999 • 34 citations

Pycnogenol Improves Learning Impairment and Memory Deficit in Senescence-Accelerated Mice

1999 • 17 citations

Effects of Aminoguanidine on Adhesion Molecule Expression of Human Endothelial Cells

1997 • 13 citations