On the nature of origins of DNA replication in eukaryotes

The localization of replication origins on ARS plasmids in S. cerevisiae

1987 • 1,051 citations

A Yeast Chromosomal Origin of DNA Replication Defined by Multiple Functional Elements

1992 • 634 citations

A replication fork barrier at the 3′ end of yeast ribosomal RNA genes

1988 • 555 citations

Nuclear reconstitution in vitro: Stages of assembly around protein-free DNA

1987 • 550 citations

Mapping replicational sites in the eucaryotic cell nucleus.

1989 • 520 citations

A model for initiation at origins of DNA replication

1988 • 452 citations

The in vivo replication origin of the yeast 2μm plasmid

1987 • 437 citations

Binding and unwinding—How T antigen engages the SV40 origin of DNA replication

1990 • 404 citations

Targeting the E1 Replication Protein to the Papillomavirus Origin of Replication by Complex Formation with the E2 Transactivator

1990 • 396 citations

Organization of replication of ribosomal DNA in Saccharomyces cerevisiae.

1988 • 369 citations

Transcriptional elements as components of eukaryotic origins of DNA replication

1988 • 341 citations

Identification of an origin of bidirectional DNA replication in mammalian chromosomes

1990 • 288 citations

Replication initiates in a broad zone in the amplified CHO dihydrofolate reductase domain

1990 • 287 citations

The DNA unwinding element: a novel, cis-acting component that facilitates opening of the Escherichia coli replication origin.

1989 • 233 citations

Introduction of cloned DNA into sea urchin egg cytoplasm: Replication and persistence during embryogenesis

1985 • 229 citations

Studies on Scaffold Attachment Sites and Their Relation to Genome Function

1990 • 210 citations

Lack of specific sequence requirement for DNA replication in Xenopus eggs compared with high sequence specificity in yeast

1984 • 203 citations

The ease of DNA unwinding as a determinant of initiation at yeast replication origins

1988 • 193 citations

Replication occurs at discrete foci spaced throughout nuclei replicating in vitro

1989 • 192 citations

Activation of Replication Origins within Yeast Chromosomes

1991 • 185 citations

Close association of a DNA replication origin and anARSelement on chromosome III of the yeast,Saccharomyces cerevisiae

1988 • 175 citations

Multiple replication origins are used during Drosophila chorion gene amplification.

1990 • 170 citations

Evidence suggesting that the ARS elements associated with silencers of the yeast mating-type locus HML do not function as chromosomal DNA replication origins.

1991 • 169 citations

Amplification enhancers and replication origins in the autosomal chorion gene cluster of Drosophila.

1989 • 161 citations

Mapping of replication initiation sites in mammalian genomes by two-dimensional gel analysis: stabilization and enrichment of replication intermediates by isolation on the nuclear matrix.

1991 • 153 citations

An initiation zone of chromosomal DNA replication located upstream of the c-myc gene in proliferating HeLa cells.

1990 • 152 citations

Autonomous DNA replication in human cells is affected by the size and the source of the DNA.

1991 • 143 citations

Emetine allows identification of origins of mammalian DNA replication by imbalanced DNA synthesis, not through conservative nucleosome segregation.

1991 • 140 citations

Replication initiates at multiple locations on an autonomously replicating plasmid in human cells.

1991 • 133 citations

Intramolecular DNA triplexes, bent DNA and DNA unwinding elements in the initiation region of an amplified dihydrofolate reductase replicon

1990 • 129 citations

Mapping an origin of DNA replication at a single-copy locus in exponentially proliferating mammalian cells.

1990 • 128 citations

Autonomous replication of a DNA fragment containing the chromosomal replication origin of the human c-myc gene

1990 • 120 citations

Control of rDNA replication in Tetrahymena involves a cis-acting upstream repeat of a promoter element

1986 • 117 citations

DNA helical stability accounts for mutational defects in a yeast replication origin.

1992 • 107 citations

Autonomous replication and addition of telomerelike sequences to DNA microinjected into Paramecium tetraurelia macronuclei.

1988 • 95 citations

Identification and purification of a protein that binds the yeast ARS consensus sequence

1991 • 94 citations

Replication of the extrachromosomal ribosomal RNA genes of Tetrahymena thermophilia

1981 • 93 citations

Analysis of chromosomal replicons in early embryos ofDrosophila melanogasterby two-dimensional gel electrophoresis

1991 • 92 citations

Bent DNA functions as a replication enhancer in Saccharomyces cerevisiae.

1988 • 82 citations

Localization and DNA sequence of a replication origin in the rhodopsin gene locus of Chinese hamster cells

1992 • 76 citations

The two faces of higher eukaryotic DNA replication origins

1990 • 73 citations

A single-stranded DNA binding protein from S. cerevisiae specifically recognizes the T-rich strand of the core sequence of ARS elements and discriminates against mutant sequences.

1991 • 68 citations

Conserved DNA structures in origins of replication

1990 • 65 citations

Replication of Ribosomal DNA in Xenopus laevis

1981 • 60 citations

A specific replication origin in the chromosomal rDNA of Lytechinus variegatus

1982 • 58 citations

Persistence and replication of plasmid DNA microinjected into early embryos of Xenopus laevis

1988 • 51 citations

Sequences near the origin of replication of the DHFR locus of Chinese hamster ovary cells adopt left-handed Z-DNA and triplex structures.

1990 • 51 citations

Classes of autonomously replicating sequences are found among early-replicating monkey DNA

1991 • 51 citations

Electron microscopic analysis of replicating DNA of sea urchin embryos

1978 • 48 citations

Amplification of tandemly repeated origin control sequences confers a replication advantage on rDNA replicons in Tetrahymena thermophila.

1990 • 42 citations

Plasmids bearing mammalian DNA-replication origin-enriched (ors) fragments initiate semiconservative replication in a cell-free system

1991 • 38 citations

Replication forks are underrepresented in chromosomal DNA of Xenopus laevis embryos.

1986 • 36 citations

Single-strand-binding factor(s) which interact with ARS1 of Saccharomyces cerevisiae

1990 • 32 citations

Distinct mouse DNA sequences enable establishment and persistence of plasmid DNA polymers in mouse cells

1989 • 21 citations

Initiation of DNA Replication in Eukaryotes

1985 • 21 citations

Control of Animal Cell Proliferation

1987 • 17 citations

Differential compartmentalization of plasmid DNA microinjected into Xenopus laevis embryos relates to replication efficiency.

1991 • 14 citations

Activation of DNA Synthesis during Early Embryogenesis

1985 • 13 citations