DNA helical stability accounts for mutational defects in a yeast replication origin.

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

A rapid boiling method for the preparation of bacterial plasmids

1981 • 3,334 citations

Predicting DNA duplex stability from the base sequence.

1986 • 1,800 citations

A dye-buoyant-density method for the detection and isolation of closed circular duplex DNA: the closed circular DNA in HeLa cells.

1967 • 1,317 citations

The localization of replication origins on ARS plasmids in S. cerevisiae

1987 • 1,051 citations

Calculating thermodynamic data for transitions of any molecularity from equilibrium melting curves

1987 • 1,037 citations

Isolation and characterisation of a yeast chromosomal replicator

1979 • 795 citations

Duplex opening by dnaA protein at novel sequences in initiation of replication at the origin of the E. coli chromosome

1988 • 678 citations

Physicochemical studies on polydeoxyribonucleotides containing defined repeating nucleotide sequences

1970 • 550 citations

The in vivo replication origin of the yeast 2μm plasmid

1987 • 437 citations

Binding and unwinding—How T antigen engages the SV40 origin of DNA replication

1990 • 404 citations

Organization of replication of ribosomal DNA in Saccharomyces cerevisiae.

1988 • 369 citations

Localization and Sequence Analysis of Yeast Origins of DNA Replication

1983 • 364 citations

Yeast chromosome replication and segregation

1988 • 250 citations

The DNA unwinding element: a novel, cis-acting component that facilitates opening of the Escherichia coli replication origin.

1989 • 233 citations

Deletion mutations affecting autonomously replicating sequence ARS1 of Saccharomyces cerevisiae.

1984 • 210 citations

A yeast replication origin consists of multiple copies of a small conserved sequence

1988 • 194 citations

The ease of DNA unwinding as a determinant of initiation at yeast replication origins

1988 • 193 citations

Close association of a DNA replication origin and anARSelement on chromosome III of the yeast,Saccharomyces cerevisiae

1988 • 175 citations

Mutational Analysis of the Consensus Sequence of a Replication Origin from Yeast Chromosome III

1990 • 174 citations

Stable DNA unwinding, not "breathing," accounts for single-strand-specific nuclease hypersensitivity of specific A+T-rich sequences.

1988 • 165 citations

Initiation protein induced helix destabilization at the λ origin: A prepriming step in DNA replication

1988 • 147 citations

New beginnings in studies of eukaryotic DNA replication origins

1989 • 139 citations

Intramolecular DNA triplexes, bent DNA and DNA unwinding elements in the initiation region of an amplified dihydrofolate reductase replicon

1990 • 129 citations

Organization of Replication of Ribosomal DNA in Saccharomyces cerevisiae

1988 • 118 citations

Fine-structure analysis of the DNA sequence requirements for autonomous replication of Saccharomyces cerevisiae plasmids.

1986 • 113 citations

A DNA replication enhancer in Saccharomyces cerevisiae.

1990 • 100 citations

DNA sequence analysis ofARSelements from chromosome III ofSaccharomyces cerevisiae: identification of a new conserved sequence

1986 • 83 citations

The two faces of higher eukaryotic DNA replication origins

1990 • 73 citations

Deletion Mutations Affecting Autonomously Replicating Sequence ARS1 of Saccharomyces cerevisiae

1984 • 71 citations

Yeast regulatory sequences preferentially adopt a non-B conformation in supercoiled DNA

1987 • 60 citations

Thermal energy suppresses mutational defects in DNA unwinding at a yeast replication origin.

1990 • 60 citations

Mung bean nuclease cleavage of a dA + dT-rich sequence or an inverted repeat sequence in supercoiled PM2 DNA depends on ionic environment

1984 • 50 citations

Simian virus 40 origin auxiliary sequences weakly facilitate T-antigen binding but strongly facilitate DNA unwinding.

1990 • 46 citations

Fine-Structure Analysis of the DNA Sequence Requirements for Autonomous Replication of Saccharomyces cerevisiae Plasmids

1986 • 41 citations

Action of mung bean nuclease on supercoiled PM2 DNA.

1982 • 38 citations

Interaction of the H4 autonomously replicating sequence core consensus sequence and its 3'-flanking domain.

1989 • 37 citations

Interaction of the H4 Autonomously Replicating Sequence Core Consensus Sequence and Its 3′-Flanking Domain

1989 • 22 citations