Ligand-Independent Actions of the Vitamin D Receptor Maintain Hair Follicle Homeostasis

The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed

1998 • 1,391 citations

Targeted ablation of the vitamin D receptor: An animal model of vitamin D-dependent rickets type II with alopecia

1997 • 933 citations

Targeted ablation of the 25-hydroxyvitamin D 1α-hydroxylase enzyme: Evidence for skeletal, reproductive, and immune dysfunction

2001 • 623 citations

Normalization of Mineral Ion Homeostasis by Dietary Means Prevents Hyperparathyroidism, Rickets, and Osteomalacia, But Not Alopecia in Vitamin D Receptor-Ablated Mice¹

1998 • 514 citations

Point mutations in the Human Vitamin D Receptor Gene Associated with Hypocalcemic Rickets

1988 • 490 citations

Alopecia Universalis Associated with a Mutation in the Human hairless Gene

1998 • 415 citations

Cloning of Human 25-Hydroxyvitamin D-1α-Hydroxylase and Mutations Causing Vitamin D-Dependent Rickets Type 1

1997 • 398 citations

Targeted Inactivation of the 25-Hydroxyvitamin D3-1α-Hydroxylase Gene (CYP27B1) Creates an Animal Model of Pseudovitamin D-Deficiency Rickets*

2001 • 385 citations

The Polymorphic N Terminus in Human Vitamin D Receptor Isoforms Influences Transcriptional Activity by Modulating Interaction with Transcription Factor IIB

2000 • 367 citations

Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice.

1989 • 365 citations

The Vitamin D Receptor and the Syndrome of Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets*

1999 • 363 citations

Inactivating Mutations in the 25-Hydroxyvitamin D₃1α-Hydroxylase Gene in Patients with Pseudovitamin D–Deficiency Rickets

1998 • 360 citations

Deletion of Deoxyribonucleic Acid Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D

2002 • 277 citations

Retinoid X receptors stimulate and 9-cis retinoic acid inhibits 1,25-dihydroxyvitamin D3-activated expression of the rat osteocalcin gene.

1993 • 272 citations

SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers.

1996 • 244 citations

Physical and Functional Interaction between the Vitamin D Receptor and Hairless Corepressor, Two Proteins Required for Hair Cycling

2003 • 215 citations

Overexpression of parathyroid hormone-related protein in the skin of transgenic mice interferes with hair follicle development.

1994 • 210 citations

Genetics of Vitamin D 1α-Hydroxylase Deficiency in 17 Families

1998 • 189 citations

The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor

2001 • 182 citations

Cloning, Genomic Organization, Alternative Transcripts and Mutational Analysis of the Gene Responsible for Autosomal Recessive Universal Congenital Alopecia

1998 • 156 citations

Evidence for Ligand-Dependent Intramolecular Folding of the AF-2 Domain in Vitamin D Receptor-Activated Transcription and Coactivator Interaction

1997 • 154 citations

Metabolic and cellular analysis of alopecia in vitamin D receptor knockout mice

2001 • 139 citations

Baculovirus-mediated expression of the human vitamin D receptor. Functional characterization, vitamin D response element interactions, and evidence for a receptor auxiliary factor.

1991 • 128 citations

Targeting Expression of the Human Vitamin D Receptor to the Keratinocytes of Vitamin D Receptor Null Mice Prevents Alopecia

2001 • 116 citations

The Thyroid Hormone-Regulated Corepressor Hairless Associates with Histone Deacetylases in Neonatal Rat Brain

2002 • 113 citations

The Interaction of the Vitamin D Receptor with Nuclear Receptor Corepressors and Coactivators

1998 • 109 citations

Evaluation of Keratinocyte Proliferation and Differentiation in Vitamin D Receptor Knockout Mice*

2000 • 108 citations

Hair loss and cyst formation in hairless and rhino mutant mice

1971 • 107 citations

ANALYSIS OF THE RELATION BETWEEN ALOPECIA AND RESISTANCE TO 1,25‐DIHYDROXYVITAMIN D

1986 • 100 citations

Hair follicle expression of 1,25-dihydroxyvitamin D3 receptors during the murine hair cycle

2006 • 93 citations

A Novel Mutation in Helix 12 of the Vitamin D Receptor Impairs Coactivator Interaction and Causes Hereditary 1,25-Dihydroxyvitamin D-Resistant Rickets without Alopecia

2002 • 91 citations

Two novel 1α-hydroxylase mutations in French-Canadians with vitamin D dependency rickets type I

1998 • 86 citations

Ligand occupancy is not required for vitamin D receptor and retinoid receptor-mediated transcriptional activation.

1995 • 66 citations

Targeted Expression of Human Vitamin D Receptor in the Skin Promotes the Initiation of the Postnatal Hair Follicle Cycle and Rescues the Alopecia in Vitamin D Receptor Null Mice

2002 • 59 citations

What controls hair follicle cycling?

1999 • 58 citations

Association with Ets-1 Causes Ligand- and AF2-Independent Activation of Nuclear Receptors

2000 • 51 citations

Studies on the repression of basal transcription (silencing) by artificial and natural human thyroid hormone receptor-beta mutants.

1995 • 44 citations