Structure and Function of a Human Insulin-like Growth Factor-I Gene Promoter

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 • 4,669 citations

Firefly luciferase gene: structure and expression in mammalian cells.

1987 • 3,088 citations

Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA

1985 • 2,505 citations

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1987 • 2,107 citations

Insulin-Like Growth Factors I and II. Peptide, Messenger Ribonucleic Acid and Gene Structures, Serum, and Tissue Concentrations*

1989 • 1,796 citations

Regulation of Inducible and Tissue-Specific Gene Expression

1987 • 1,640 citations

The “initiator” as a transcription control element

1989 • 1,597 citations

Actions of Insulin-Like Growth Factors

1985 • 1,141 citations

Identification of two distinct regulatory regions adjacent to the human β-interferon gene

1983 • 1,076 citations

Heat shock factor and the heat shock response

1991 • 615 citations

Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines.

1989 • 614 citations

Regulation of insulin-like growth factor I gene expression by growth hormone.

1986 • 558 citations

[72] Identification of regulatory elements of cloned genes with functional assays

1987 • 477 citations

Transcription factors that activate the Ultrabithorax promoter in developmentally staged extracts

1988 • 454 citations

Promoters for housekeeping genes

1986 • 412 citations

Analysis of Insulin-Like Growth Factor I Gene Expression in Malignancy: Evidence for a Paracrine Role in Human Breast Cancer

1989 • 403 citations

Organization and sequence of the human insulin-like growth factor I gene. Alternative RNA processing produces two insulin-like growth factor I precursor peptides.

1986 • 371 citations

Two insulin-like growth factor I messenger RNAs are expressed in human liver.

1986 • 260 citations

Structure, Evolution, Expression and Regulation of Insulin-Like Growth Factors I and II

1991 • 247 citations

Two distinct factors interact with the promoter regions of several liver-specific genes.

1988 • 226 citations

Sequences of liver cDNAs encoding two different mouse insulin-like growth factor I precursors

1986 • 215 citations

Isolation of the human insulin-like growth factor genes: insulin-like growth factor II and insulin genes are contiguous.

1985 • 212 citations

Estradiol Regulation of Insulin-Like Growth Factor-I Expression in Osteoblastic Cells: Evidence for Transcriptional Control

1991 • 138 citations

Acute regulation of insulin-like growth factor-I gene expression by growth hormone during adipose cell differentiation.

1987 • 120 citations

An inducible nuclear factor binds to a growth hormone-regulated gene.

1990 • 109 citations

Structure of the chicken insulin-like growth factor I gene reveals conserved promoter elements

1991 • 96 citations

Organization of the human genes for insulin‐like growth factors I and II

1986 • 88 citations

Regulation of insulin-like growth factor I gene expression in the human macrophage-like cell line U937.

1990 • 86 citations

Transcription initiation in the two leader exons of the rat IGF-I gene occurs from disperse versus localized sites

1991 • 85 citations

Cloning and characterization of the proximal promoter region of the rat insulin-like growth factor I (IGF-I) receptor gene

1990 • 84 citations

Complexities of gene regulation by cAMP

1989 • 83 citations

Identification of multiple transcription start sites in the human insulin-like growth factor-I gene

1991 • 82 citations

Rat IGF-I cDNA's contain multiple 5′-untranslated regions

1987 • 76 citations

The Size Heterogeneity of Rat Insulin-Like Growth Factor-I mRNAs is Due Primarily to Differences in the Length of 3′-Untranslated Sequence

1989 • 73 citations

Complete characterization of the human IGF‐I nucleotide sequence isolated from a newly constructed adult liver cDNA library

1986 • 72 citations

Cloning of Ovine Insulin-Like Growth Factor-I cDNAs: Heterogeneity in the mRNA Population

1989 • 65 citations

Complete nucleotide sequence of the high molecular weight human IGF-I mRNA

1991 • 63 citations

A Novel Human Insulin-Like Growth Factor I Messenger RNA is Expressed in Normal and Tumor Cells

1990 • 59 citations

Nucleotide sequence of a genomic fragment of the rat IGF-I gene spanning an alternate 5′ non coding exon

1989 • 42 citations