Thrombin and activators of protein kinase C modulate secretory responses of permeabilised human platelets induced by Ca²⁺

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Methods of Enzymatic Analysis

1975 • 20,446 citations

DETERMINATION OF SERUM PROTEINS BY MEANS OF THE BIURET REACTION

1949 • 16,078 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Methods of enzymatic analysis

1966 • 4,073 citations

New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures

1980 • 2,218 citations

Platelet Sequestration in Man. I. Methods*

1964 • 830 citations

Diacylglycerol and phorbol ester stimulate secretion without raising cytoplasmic free calcium in human platelets

1983 • 589 citations

Structural similarities between the Ca2+-dependent regulatory proteins of 3':5'-cyclic nucleotide phosphodiesterase and actomyosin ATPase.

1976 • 517 citations

Calcium-dependence of catecholamine release from bovine adrenal medullary cells after exposure to intense electric fields

1982 • 500 citations

Handbook of Biochemistry

2018 • 437 citations

Human platelet myosin light chain kinase requires the calcium-binding protein calmodulin for activity.

1979 • 381 citations

Calcium-dependent exocytosis in bovine adrenal medullary cells with leaky plasma membranes

1978 • 315 citations

The release of nucleotides, 5‐hydroxytryptamine and enzymes from human blood platelets during aggregation

1968 • 312 citations

Phorbol ester-induced activation of human platelets is associated with protein kinase C phosphorylation of myosin light chains

1983 • 265 citations

Thrombin-induced protein phosphorylation in human platelets.

1975 • 254 citations

Relationship between phosphorylation of blood platelet proteins and secretion of platelet granule constituents I. Effects of different aggregating agents

1977 • 216 citations

Specificity of the Fatty Acyl Moieties of Diacylglycerol for the Activation of Calcium-Activated, Phospholipid-Dependent Protein Kinase1

1982 • 182 citations

Purification and characterization of the 47,000-dalton protein phosphorylated during degranulation of human platelets.

1983 • 179 citations

Calcium, phospholipid turnover and transmembrane signalling

1983 • 154 citations

Effects of collagen, ionophore A23187 and prostaglandin E1 on the phosphorylation of specific proteins in blood platelets

1979 • 150 citations

Cyclic nucleotides control a system which regulates Ca2+ sensitivity of platelet secretion

1984 • 147 citations

Thrombin-induced platelet responses differ in requirement for receptor occupancy. Evidence for tight coupling of occupancy and compartmentalized phosphatidic acid formation.

1981 • 101 citations

Agonist selectivity and second messenger concentration in Ca2+-mediated secretion

1982 • 100 citations

Direct evidence for a role for Ca2+ in amine storage granule secretion by human platelets

1980 • 99 citations

Investigation of the release reaction in platelets exposed to phorbol myristate acetate.

1974 • 93 citations

Content and thrombin-induced release of acid hydrolases in gel-filtered platelets from patients with storage pool disease

1975 • 83 citations

Determination of acid hydrolases in human platelets

1980 • 78 citations

Thrombin-induced Platelet Release Reaction and Platelet Lysosomes

1968 • 55 citations

Platelets: Cellular Response Mechanisms and their Biological Significance

1981 • 48 citations

Helical microtubular arrays in onion root hairs

1983 • 45 citations

Modulation of Platelet Function by Prostaglandins: Characterization of Platelet Receptors for Stimulatory Prostaglandins and the Role of Arachidonate Metabolites in Platelet Degranulation Responses

1979 • 15 citations