Thrombin-induced platelet responses differ in requirement for receptor occupancy. Evidence for tight coupling of occupancy and compartmentalized phosphatidic acid formation.

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

Production of diglyceride from phosphatidylinositol in activated human platelets.

1979 • 727 citations

Inhibition of arachidonic acid release from cells as the biochemical action of anti-inflammatory corticosteroids.

1976 • 573 citations

Metabolism of Molecular Species of Diacylglycerophospholipids

1978 • 331 citations

Determination of ATP and ADP in blood platelets: A modification of the firefly luciferase assay for plasma

1972 • 330 citations

Stimulation of phosphatidic acid production in platelets precedes the formation of arachidonate and parallels the release of serotonin

1979 • 285 citations

Studies on gel-filtered human platelets: isolation and characterization in a medium containing no added Ca2+, Mg2+, or K+.

1975 • 181 citations

Kinetics of the thrombin-induced release of calcium(II) by platelets

1973 • 164 citations

The fatty acid composition of phosphatidylinositol from thrombin-stimulated human platelets.

1981 • 125 citations

Release of intracellular membrane-bound calcium precedes the onset of stimulus-induced exocytosis in platelets

1980 • 109 citations

Changes in ³²P‐Content of Phosphatidic Acid and the Phosphoinositides of Rabbit Platelets during Aggregation Induced by Collagen or Thrombin

1974 • 101 citations

Identification of cytidine diphosphate-diglyceride in the pineal gland of the rat and its accumulation in the presence of DL-propranolol.

1975 • 99 citations

Secretory mechanisms. Behaviour of adenine nucleotides during the platelet release reaction induced by adenosine diphosphate and adrenaline

1972 • 96 citations

Behaviour of endogenous and newly absorbed serotonin in the platelet release reaction

1973 • 81 citations

Determination of acid hydrolases in human platelets

1980 • 78 citations

Dissociation of thrombin from platelets by hirudin. Evidence for receptor processing.

1979 • 66 citations

Diglyceride kinase in human platelets

1973 • 60 citations

Adenine nucleotide metabolism of blood platelets

1977 • 53 citations

Protein phosphorylation in platelets stimulated by immobilized thrombin at 37 degrees and 4 degrees C.

1980 • 50 citations

Factors influencing the initiation and the extrusion phase of the platelet release reaction

1972 • 37 citations

Simultaneous measurement of aggregation, secretion, oxygen uptake, proton production, and intracellular metabolites in the same platelet suspension

1979 • 36 citations