Multi‐step DNA cleavage in rat liver nuclei is inhibited by thiol reactive agents

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

Biochemical Effects of Mercury, Cadmium, and Lead

1972 • 1,464 citations

Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death.

1984 • 1,441 citations

Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

1993 • 1,144 citations

Apoptosis: The Biochemistry and Molecular Biology of Programmed Cell Death*

1993 • 1,005 citations

Death and the cell

1986 • 616 citations

A biochemical hallmark of apoptosis: Internucleosomal degradation of the genome

1992 • 523 citations

Calpain activation in apoptosis

1994 • 445 citations

Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation.

1993 • 419 citations

Topoisomerase II-reactive chemotherapeutic drugs induce apoptosis in thymocytes.

1991 • 392 citations

Spectrophotometric assay of thiols

1987 • 301 citations

Calcium-activated DNA Fragmentation in Rat Liver Nuclei

1989 • 281 citations

Periodicity of DNA folding in higher order chromatin structures.

1990 • 275 citations

Endonuclease Activities Associated with High Molecular Weight and Internucleosomal DNA Fragmentation in Apoptosis

1994 • 173 citations

[36] Reactions with N-ethylmaleimide and p-mercuribenzoate

1972 • 161 citations

Gel electrophoresis of nucleic acids: a practical approach

1982 • 148 citations

Calcium/magnesium-dependent endonuclease from human spleen: Purification, properties, and role in apoptosis

1993 • 123 citations

Mg(2+)-dependent cleavage of DNA into kilobase pair fragments is responsible for the initial degradation of DNA in apoptosis.

1994 • 116 citations

Role of proteolysis in apoptosis: involvement of serine proteases in internucleosomal DNA fragmentation in immature thymocytes

1993 • 109 citations

Formation of disulfides with diamide

1987 • 100 citations

Cadmium- and Zinc-Mediated Changes of the Ca2+-Dependent Endonuclease in Apoptosis

1993 • 99 citations

Formation of 50 kbp chromatin fragments in isolated liver nuclei is mediated by protease and endonuclease activation

1994 • 96 citations

Gel electrophoresis of nucleic acids: A practical approach

1991 • 92 citations

Inhibitors of proteases prevent endonucleolysis accompanying apoptotic death of HL-60 leukemic cells and normal thymocytes.

1992 • 86 citations

Properties of some nuclear nucleases of rat thymocytes and their changes in radiation‐induced apoptosis

1993 • 68 citations

Use of serine‐protease inhibitors as probes for the different proteolytic activities of the rat liver multicatalytic proteinase complex

1992 • 44 citations

Early mobilization of Ca2+ is not required for glucocorticoid-induced apoptosis in thymocytes.

1993 • 39 citations

DNA fragmentation into 200–250 and/or 30–50 kilobase pair fragments in rat liver nuclei is stimulated by Mg²⁺ alone and Ca²⁺/Mg²⁺ but not by Ca²⁺ alone

1994 • 32 citations

Gel electrophoresis of nucleic acids: A practical approach (2nd edition)

1991 • 17 citations

Purification and properties of a thiol protease from rat liver nuclei

1984 • 7 citations

[Polarographic method of determination of adrenalin and noradrenalin and of substances with certain properties of adrenalin oxidation products].

1959 • 6 citations