Eukaryotic transcription factors

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

Zinc Finger-DNA Recognition: Crystal Structure of a Zif268-DNA Complex at 2.1 Å

1991 • 2,034 citations

Crystal structure of a yeast TBP/TATA-box complex

1993 • 1,082 citations

Co-crystal structure of TBP recognizing the minor groove of a TATA element

1993 • 1,039 citations

Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain

1993 • 723 citations

Crystal Structure of a Five-Finger GLI-DNA Complex: New Perspectives on Zinc Fingers

1993 • 679 citations

Structure of NF-κB p50 homodimer bound to a κB site

1995 • 564 citations

Crystal structure of a TFIIB–TBP–TATA-element ternary complex

1995 • 542 citations

Structure of the NF-κB p50 homodimer bound to DNA

1995 • 525 citations

Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules

1994 • 506 citations

A General Strategy for Selecting High-Affinity Zinc Finger Proteins for Diverse DNA Target Sites

1997 • 327 citations

Crystal structure of a yeast TFIIA/TBP/DNA complex

1996 • 312 citations

A new pattern for helix–turn–helix recognition revealed by the PU.l ETS–domain–DNA complex

1996 • 307 citations

The Crystal Structure of the DNA-Binding Domain of Yeast RAP1 in Complex with Telomeric DNA

1996 • 306 citations

How Proteins Recognize the TATA Box

1996 • 301 citations

Crystal structure of a human TATA box-binding protein/TATA element complex.

1996 • 281 citations

TATA-binding protein-independent initiation: YY1, TFIIB, and RNA polymerase II direct basal transcription on supercoiled template DNA

1994 • 275 citations

Crystal Structure of the Yeast TFIIA/TBP/DNA Complex

1996 • 263 citations

Crystal Structure of the MATa1/MATα2 Homeodomain Heterodimer Bound to DNA

1995 • 260 citations

The solution structure of a specific GAGA factor–DNA complex reveals a modular binding mode

1997 • 219 citations

1.9 Å resolution refined structure of TBP recognizing the minor groove of TATAAAAG

1994 • 206 citations

Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility.

1997 • 205 citations

Cocrystal structure of YY1 bound to the adeno-associated virus P5 initiator

1996 • 187 citations

Modulation of Transcription Factor Ets-1 DNA Binding: DNA-Induced Unfolding of an α Helix

1995 • 177 citations

The Crystal Structure of a Hyperthermophilic Archaeal TATA-box Binding Protein

1996 • 170 citations

The crystal structure of an intact human Max–DNA complex: new insights into mechanisms of transcriptional control

1997 • 162 citations

Solution structure of the ETS domain from murine Ets-1: a winged helix-turn-helix DNA binding motif.

1996 • 157 citations

The 2.1-Å crystal structure of an archaeal preinitiation complex: TATA-box-binding protein/transcription factor (II)B core/TATA-box

1997 • 156 citations

Synergy between adjacent zinc fingers in sequence-specific DNA recognition

1997 • 148 citations

Characterization of the Cooperative Function of Inhibitory Sequences in Ets-1

1996 • 145 citations

Oct-1 POU domain-DNA interactions: cooperative binding of isolated subdomains and effects of covalent linkage.

1996 • 136 citations

Structures of Zinc Finger Domains from Transcription Factor Sp1

1997 • 133 citations

Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA

1997 • 126 citations

The solution structure of the human ETS1-DNA complex reveals a novel mode of binding and true side chain intercalation

1995 • 108 citations

High-resolution mapping of nucleoprotein complexes by site-specific protein-DNA photocrosslinking: organization of the human TBP-TFIIA-TFIIB-DNA quaternary complex.

1996 • 107 citations

YY1 transcriptional initiator: Protein interactions and association with a DNA site containing unpaired strands

1996 • 103 citations

Radical mutations reveal TATA-box binding protein surfaces required for activated transcription in vivo.

1996 • 97 citations

Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc

1997 • 96 citations

New Insights on DNA Recognition by ets Proteins from the Crystal Structure of the PU.1 ETS Domain-DNA Complex

1996 • 80 citations

Structural coupling of the inhibitory regions flanking the ETS domain of murine Ets‐1

1996 • 66 citations

Transcription Factor IIA Mutations Show Activator-specific Defects and Reveal a IIA Function Distinct from Stimulation of TBP-DNA Binding

1996 • 48 citations

Role of base‐backbone and base‐base interactions in alternating DNA conformations

1996 • 44 citations

Dual role of the nuclear factor of activated T cells insert region in DNA recognition and cooperative contacts to activator protein 1

1997 • 43 citations

Crystal structure of the DNA-binding domain of Mbp1, a transcription factor important in cell-cycle control of DNA synthesis

1997 • 41 citations

The solution structure of the first zinc finger domain of SWI5: a novel structural extension to a common fold

1996 • 39 citations

Analysis of Co-Crystal Structures to Identify the Stereochemical Determinants of the Orientation of TBP on the TATA Box

1996 • 21 citations

The Solution Structure of the Human ETS1-DNA Complex Reveals a Novel Mode of Binding and True Side Chain Intercalation

1996 • 9 citations