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Krox-20 is a key regulator of rhombomere-specific gene expression in the developing hindbrain

Data up to Jan 2025

Published1997
Citations94
References55

Total Citations Per Year

Abstract

References (55)

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Segmental patterns of neuronal development in the chick hindbrain

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1994 • 486 citations

Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20.

1993 • 469 citations

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1992 • 461 citations

Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain

1993 • 452 citations

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Expression of truncated Sek-1 receptor tyrosine kinase disrupts the segmental restriction of gene expression in the Xenopus and zebrafish hindbrain

1995 • 315 citations

The zinc finger gene Krox20 regulates HoxB2 (Hox2.8) during hindbrain segmentation

1993 • 297 citations

Base sequence discrimination by zinc-finger DNA-binding domains

1991 • 261 citations

Even-numbered rhombomeres control the apoptotic elimination of neural crest cells from odd-numbered rhombomeres in the chick hindbrain

1993 • 260 citations

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1994 • 252 citations

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1988 • 234 citations

A receptor protein tyrosine kinase implicated in the segmental patterning of the hindbrain and mesoderm

1992 • 226 citations

Segment-specific expression of a homoeobox-containing gene in the mouse hindbrain

1989 • 214 citations

Segmental migration of the hindbrain neural crest does not arise from its segmental generation

1993 • 210 citations

The segment-specific gene Krox-20 encodes a transcription factor with binding sites in the promoter region of the Hox-1.4 gene.

1990 • 190 citations

Segmental expression of Hoxa-2 in the hindbrain is directly regulated by Krox-20

1996 • 188 citations

Reorganization of Pontine Rhythmogenic Neuronal Networks in Krox-20 Knockout Mice

1996 • 178 citations

Immunolocalization of the Nuk receptor tyrosine kinase suggests roles in segmental patterning of the brain and axonogenesis.

1994 • 174 citations

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1994 • 172 citations

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1993 • 170 citations

Violation of cell lineage restriction compartments in the chick hindbrain

1994 • 170 citations

EctopicHoxa-1induces rhombomere transformation in mouse hindbrain

1994 • 166 citations

Segmental repetition of neuronal phenotype sets in the chick embryo hindbrain

1993 • 156 citations

Segmental and neuronal architecture of the hindbrain of Krox-20 mouse mutants

1997 • 137 citations

Several receptor tyrosine kinase genes of the Eph family are segmentally expressed in the developing hindbrain

1994 • 135 citations

Expression of inhibin subunits and follistatin during postimplantation mouse development: decidual expression of activin and expression of follistatin in primitive streak, somites and hindbrain

1994 • 126 citations

Rhombomeric origin and rostrocaudal reassortment of neural crest cells revealed by intravital microscopy

1995 • 125 citations

The conserved role of Krox-20 in directing Hox gene expression during vertebrate hindbrain segmentation.

1996 • 123 citations

Analysis of the murine Hox-2.7 gene: conserved alternative transcripts with differential distributions in the nervous system and the potential for shared regulatory regions.

1992 • 123 citations

Mouse cellular retinoic acid binding protein: cloning, complementary DNA sequence, and messenger RNA expression during the retinoic acid-induced differentiation of F9 wild type and RA-3-10 mutant teratocarcinoma cells.

1989 • 122 citations

Progressive Spatial Restriction ofSek-1andKrox-20Gene Expression during Hindbrain Segmentation

1996 • 119 citations

Nucleotide sequence and expression in vitro of cDNA derived from mRNA of int-1, a provirally activated mouse mammary oncogene.

1985 • 110 citations

Defective bone formation in Krox-20 mutant mice

1996 • 108 citations

The expression of the receptor-protein tyrosine kinase gene, eck, is highly restricted during early mouse development

1994 • 98 citations

The Eck receptor tyrosine kinase is implicated in pattern formation during gastrulation, hindbrain segmentation and limb development.

1994 • 78 citations

Telling Axons Where to Grow: A Role for Eph Receptor Tyrosine Kinases in Guidance

1995 • 76 citations

Hoxb-2 transcriptional activation in rhombomeres 3 and 5 requires an evolutionarily conserved cis-acting element in addition to the Krox-20 binding site.

1996 • 75 citations

Embryo brain kinase: a novel gene of the eph/elk receptor tyrosine kinase family

1995 • 63 citations

Interactions between rhombomeres modulate Krox-20 and follistatin expression in the chick embryo hindbrain

1996 • 53 citations

Mapping functional regions of the segment-specific transcription factor Krox-20

1992 • 46 citations

Molecular mechanisms of segmental patterning in the vertebrate hindbrain.

1993 • 13 citations

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Krox-20 is a key regulator of rhombomere-specific gene expression in the developing… (1997) – Mechanisms of Development | Metascience Observatory Explorer