Localization and processing of outer membrane and periplasmic proteins in Escherichia coli strains harboring export-specific suppressor mutations.

Experiments in molecular genetics

1972 • 28,260 citations

The Release of Enzymes from Escherichia coli by Osmotic Shock and during the Formation of Spheroplasts

1965 • 1,490 citations

E. coli mutant pleiotropically defective in the export of secreted proteins

1981 • 512 citations

Solubilization of the Cytoplasmic Membrane of Escherichia coli by Triton X-100

1971 • 498 citations

Suppressor mutations that restore export of a protein with a defective signal sequence

1981 • 382 citations

Protein localization in E. coli: Is there a common step in the secretion of periplasmic and outer-membrane proteins?

1981 • 359 citations

Secretion of beta-lactamase requires the carboxy end of the protein

1980 • 311 citations

The mechanism of protein secretion across membranes

1980 • 285 citations

Proteins of the Outer Membrane of Gram-Negative Bacteria

1980 • 282 citations

Mutations which alter the function of the signal sequence of the maltose binding protein of Escherichia coli

1980 • 268 citations

Purification and characterization of leader (signal) peptidase from Escherichia coli.

1980 • 237 citations

Bacterial Outer Membranes

1981 • 212 citations

Different exported proteins in E. coli show differences in the temporal mode of processing in vivo

1981 • 203 citations

Sequence analysis of mutations that prevent export of λ receptor, an Escherichia coli outer membrane protein

1980 • 195 citations

A single amino acid substitution in a histidine-transport protein drastically alters its mobility in sodium dodecyl sulfate-polyacrylamide gel electrophoresis

1979 • 183 citations

Mutations affecting localization of an Escherichia coli outer membrane protein, the bacteriophage λ receptor

1980 • 153 citations

An Escherichia coli mutant with an amino acid alteration within the signal sequence of outer membrane prolipoprotein.

1978 • 131 citations

Escherichia coli mutants accumulating the precursor of a secreted protein in the cytoplasm

1979 • 129 citations

A mechanism of protein localization: the signal hypothesis and bacteria.

1980 • 127 citations

Affinity chromatographic isolation of the periplasmic maltose binding protein of Escherichia coli

1978 • 124 citations

Mutations altering the cellular localization of the phage lambda receptor, an Escherichia coli outer membrane protein.

1978 • 106 citations

A Genetic Method for Determining the Order of Events in a Biological Pathway

1973 • 103 citations

A mutation downstream from the signal peptidase cleavage site affects cleavage but not membrane insertion of phage coat protein.

1981 • 67 citations

Processing of filamentous phage pre-coat protein

1980 • 64 citations

Interaction of the cheC and cheZ gene products is required for chemotactic behavior in Escherichia coli.

1979 • 53 citations

Assembly of membrane proteins in Escherichia coli.

1980 • 16 citations

Genetic studies on mechanisms of protein localization in escherichia coli K‐12

1980 • 13 citations