A Constitutive Heat Shock Element-binding Factor Is Immunologically Identical to the Ku Autoantigen

Molecular cloning: A laboratory manual

1990 • 85,659 citations

The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen

1993 • 1,219 citations

The biology of heat shock proteins and molecular chaperones

1994 • 1,203 citations

Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation

1988 • 886 citations

Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress.

1993 • 879 citations

Chromatin as an essential part of the transcriptional mechanim

1992 • 853 citations

Steroid hormone receptors compete for factors that mediate their enhancer function

1989 • 580 citations

Mechanism of interaction between Ku protein and DNA.

1986 • 485 citations

Molecular cloning and expression of a human heat shock factor, HSF1.

1991 • 472 citations

Activation of human heat shock genes is accompanied by oligomerization, modification, and rapid translocation of heat shock transcription factor HSF1.

1993 • 455 citations

Characterization of a high molecular weight acidic nuclear protein recognized by autoantibodies in sera from patients with polymyositis-scleroderma overlap.

1981 • 430 citations

Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen.

1990 • 415 citations

Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells.

1988 • 407 citations

Trimerization of a yeast transcriptional activator via a coiled-coil motif

1989 • 392 citations

Stress-induced oligomerization and chromosomal relocalization of heat-shock factor

1991 • 391 citations

Purification and Properties of Drosophila Heat Shock Activator Protein

1987 • 388 citations

Cloning and characterization of two mouse heat shock factors with distinct inducible and constitutive DNA-binding ability.

1991 • 381 citations

Isolation of a cDNA for HSF2: evidence for two heat shock factor genes in humans.

1991 • 347 citations

Characterization of the DNA-binding protein antigen Ku recognized by autoantibodies from patients with rheumatic disorders.

1986 • 333 citations

Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks.

1993 • 311 citations

In vitro activation of heat shock transcription factor DNA-binding by calcium and biochemical conditions that affect protein conformation.

1990 • 295 citations

Activation in vitro of sequence-specific DNA binding by a human regulatory factor

1988 • 278 citations

EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single- to double-strand transitions in DNA

1993 • 247 citations

Molecular Cloning of cDNA Encoding the p70 (Ku) Lupus Autoantigen

1989 • 212 citations

Purification and characterization of a template-associated protein kinase that phosphorylates RNA polymerase II

1993 • 184 citations

Protein Denaturation during Heat Shock and Related Stress

1989 • 166 citations

Use of monoclonal antibodies for the characterization of novel DNA-binding proteins recognized by human autoimmune sera.

1985 • 156 citations

Purification and characterization of proximal sequence element-binding protein 1, a transcription activating protein related to Ku and TREF that binds the proximal sequence element of the human U1 promoter.

1990 • 141 citations

cDNA-derived Amino Acid Sequence of the 86-kDa Subunit of the Ku Antigen

1989 • 125 citations

c-Jun is phosphorylated by the DNA-dependent protein kinasein vitro; definition of the minimal kinase recognition motif

1993 • 104 citations

Heat shock protein hsp70 accelerates the recovery of heat-shocked mammalian cells through its modulation of heat shock transcription factor HSF1.

1995 • 94 citations

ANTIBODIES TO THE p70/p80 (Ku) ANTIGENS IN SYSTEMIC LUPUS ERYTHEMATOSUS

1992 • 89 citations

The nucleolar transcription activator UBF relieves Ku antigen-mediated repression of mouse ribosomal gene transcription

1993 • 80 citations

A 10S particle released from deoxyribonuclease-sensitive regions of HeLa cell nuclei contains the 86-kilodalton-70-kilodalton protein complex

1986 • 68 citations

Suppression of heat-induced hsp70 expression by the 70-kDa subunit of the human Ku autoantigen.

1995 • 56 citations

The autoantigen Ku is indistinguishable from NF IV, a protein forming multimeric protein-DNA complexes.

1990 • 52 citations

Dual control of heat shock response: involvement of a constitutive heat shock element-binding factor.

1993 • 49 citations

The DNA-activated protein kinase, DNA-PK: a potential coordinator of nuclear events.

1991 • 43 citations

Enhancer 1 binding factor, a Ku-related protein, is a positive regulator of RNA polymerase I transcription initiation.

1994 • 42 citations

The Binding Site of a Steroid Hormone Receptor-Like Protein within the Drosophila Adh Adult Enhancer Is Required for High Levels of Tissue-Specific Alcohol Dehydrogenase Expression

1992 • 34 citations

Characterization of the Factor E1BF from a Rat Hepatoma That Modulates Ribosomal RNA Gene Transcription and Its Relationship to the Human Ku Autoantigen

1993 • 29 citations

The presence of an antigen reactive with a human autoantibody inTrichosia pubescens (Diptera: Sciaridae) and its association with certain transcriptionally active regions of the genome

1990 • 26 citations

Decreased stress inducibility of the HSP68 protein in a rat hepatoma variant clone

1992 • 19 citations