Molecular diagnosis of exocrine pancreatic cancer using a percutaneous technique

Therapy of locally unresectable pancreatic carcinoma: A randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil. The gastrointestinal tumor study group

1981 • 1,038 citations

Prognostic indicators for survival after resection of pancreatic adenocarcinoma

1993 • 763 citations

Preoperative Chemoradiation and Pancreaticoduodenectomy for Adenocarcinoma of the Pancreas

1992 • 718 citations

K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization.

1993 • 656 citations

Randomised trial of endoscopic endoprosthesis versus operative bypass in malignant obstructive jaundice.

1989 • 572 citations

Endoscopic biliary endoprosthesis in the palliation of malignant obstruction of the distal common bile duct: A randomized trial

1988 • 548 citations

Factors influencing survival after pancreaticoduodenectomy for pancreatic cancer

1991 • 538 citations

K-ras and p53 gene mutations in pancreatic cancer: ductal and nonductal tumors progress through different genetic lesions.

1994 • 389 citations

Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma.

1993 • 380 citations

Detection of K-ras mutations in the stool of patients with pancreatic adenocarcinoma and pancreatic ductal hyperplasia.

1994 • 369 citations

Frequent c-Ki-ras oncogene activation in mucous cell hyperplasias of pancreas suffering from chronic inflammation.

1993 • 351 citations

Rapid detection of ras oncogenes in human tumors: applications to colon, esophageal, and gastric cancer.

1989 • 275 citations

Laparoscopy in the staging and planning of therapy for pancreatic cancer

1986 • 255 citations

Thin-section contrast-enhanced computed tomography accurately predicts the resectability of malignant pancreatic neoplasms

1994 • 247 citations

Comparative analysis of mutations in the p53 and K‐ras genes in pancreatic cancer

1994 • 235 citations

Preoperative chemoradiation, pancreaticoduodenectomy, and intraoperative radiation therapy for adenocarcinoma of the pancreatic head

1996 • 233 citations

Rapid and sensitive nonradioactive detection of mutant K-ras genes via 'enriched' PCR amplification.

1991 • 184 citations

Prevention of orthotopic human lung cancer growth by intratracheal instillation of a retroviral antisense K-ras construct.

1993 • 162 citations

Clinical application of ras gene mutation for diagnosis of pancreatic adenocarcinoma

1991 • 148 citations

Detection of point mutations in the K-ras oncogene at codon 12 in pure pancreatic juice for diagnosis of pancreatic carcinoma

1994 • 142 citations

Detection of c-K-ras mutations in fine needle aspirates from human pancreatic adenocarcinomas.

1990 • 132 citations

Fine needle aspiration of the pancreas. In quest of accuracy.

1995 • 110 citations

Identification of H-ras Mutations in Urine Sediments Complements Cytology in the Detection of Bladder Tumors

1995 • 93 citations

Significance of peritoneal cytology in patients with potentially resectable adenocarcinoma of the pancreatic head

1995 • 91 citations

Pancreatic Cancer Cell DNA Content Correlates With Long-term Survival After Pancreatoduodenectomy

1991 • 90 citations

Detection of c-Ki-ras Mutation by PCR/RFLP Analysis and Diagnosis of Pancreatic Adenocarcinomas

1993 • 85 citations

Identification of K‐ras Oncogene Mutations in the Pure Pancreatic Juice of Patients with Ductal Pancreatic Cancers

1993 • 70 citations

Reoperative Pancreaticoduodenectomy

1994 • 56 citations

Diagnosis of pancreatic adenocarcinoma by polymerase chain reaction from pancreatic secretions

1994 • 53 citations

Factors influencing survival after resection of pancreatic cancer. A DNA analysis and a histomorphologic study

1994 • 50 citations

Fine‐needle aspiration biopsy of pancreatic ductal adenocarcinoma: Loss of diagnostic accuracy with small tumors

1994 • 46 citations

Prognostic significance of DNA ploidy in adenocarcinoma of the pancreas. A flow cytometric study of paraffin-embedded specimens

1993 • 42 citations

K-ras-2 Topographic Genotyping of Pancreatic Adenocarcinoma

1994 • 38 citations

DETECTION OF K-RAS MUTATION IN NORMAL AND MALIGNANT COLONIC TISSUES BY AN ENRICHED PCR METHOD

1994 • 32 citations

Role of fine needle aspiration cytology and endoscopic biopsy in the preoperative assessment of pancreatic and peripancreatic malignancies

1994 • 29 citations

A multi-institutional comparative trial of radiation therapy alone and in combination with 5-fluorouracil for locally unresectable pancreatic carcinoma. The Gastrointestinal Tumor Study Group.

1979 • 27 citations

Detection of c-Ki-ras point mutation from pancreatic juice

1993 • 25 citations

Quantitative nuclear DNA content in fine needle aspirates of pancreatic cancer.

1991 • 20 citations

Diagnostic accuracy of fine needle aspiration cytology in pancreatic lesions. A review of 77 cases.

1993 • 20 citations

DNA aneuploidy is an independent factor of poor prognosis in pancreatic and peripancreatic cancer

1993 • 17 citations

ras oncogene detection in pre-neoplastic lesions: possible applications for diagnosis and prevention.

1992 • 13 citations

Dendritic Development in Normal Lumbar Motoneurons and Following Neonatal Nerve Crush in the Rat

1994 • 12 citations

Preoperative chemoradiation for adenocarcinoma of the pancreas: M.D. Anderson experience

1995 • 8 citations

Preoperative chemoradiation, pancreaticoduodenectomy, and intraoperative radiation therapy for adenocarcinoma of the pancreatic head: Survival and pattern of failure analysis

1995 • 2 citations

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