Opposite effects of acute and repeated administration of desmethylimipramine on adrenergic responsiveness in rat pineal gland

THE CATECHOLAMINE HYPOTHESIS OF AFFECTIVE DISORDERS: A REVIEW OF SUPPORTING EVIDENCE

1965 • 3,421 citations

Norepinephrine in Depressive Reactions

1965 • 1,127 citations

Development of β-adrenergic receptor subsensitivity by antidepressants

1977 • 727 citations

Action of various antidepressant treatments reduces reactivity of noradrenergic cyclic AMP-generating system in limbic forebrain

1975 • 599 citations

Inhibition of Uptake of Tritiated-noradrenaline in the Intact Rat Brain by Imipramine and Structurally Related Compounds

1964 • 506 citations

The fate of H3-norepinephrine in animals.

1961 • 431 citations

Stereospecific [3H](−)-alprenolol binding sites, β-adrenergic receptors and adenylate cyclase

1974 • 229 citations

β-Adrenergic Receptors in Aged Rat Brain: Reduced Number and Capacity of Pineal Gland to Develop Supersensitivity

1978 • 226 citations

The fate of 3H-iso-proterenol in the rat

1964 • 164 citations

Theoretical implications of drug-induced adaptive regulation for a biogenic amine hypothesis of affective disorder.

1974 • 164 citations

SELECTIVE STIMULATION OF ADENYL CYCLASE OF RAT PINEAL GLAND BY PHARMACOLOGICALLY ACTIVE CATECHOLAMINES

1968 • 148 citations

Desmethylimipramine-induced decrease in β-adrenergic receptor binding in rat cerebral cortex

1978 • 141 citations

Sympathetic Nerve Endings in the Pineal Gland Protect Against Acute Stress-Induced Increase in N-Acetyltransferase (EC 2.3.1.5.) Activity

1976 • 127 citations

Psychoactive drug effects on a system which generates cyclic AMP in brain

1976 • 124 citations

INFLUENCE OF IMIPRAMINE AND RELATED PSYCHOACTIVE AGENTS ON THE EFFECT OF 5-HYDROXYTRYPTAMINE AND CATECHOLAMINES ON THE CAT NICTITATING MEMBRANE.

1963 • 104 citations

The effect of tri-iodothyronine in combination with imipramine on [3H]-cyclic AMP production in slices of rat cerebral cortex

1974 • 92 citations

Advances in cyclic nucleotide research

1984 • 83 citations

Changes in Norepinephrine Turnover in Rat Brain During Chronic Administration of Imipramine and Protriptyline: A Possible Explanation for the Delay in Onset of Clinical Antidepressant Effects

1971 • 77 citations

Effects of environmental lighting and chronic denervation on the activation of adenyl cyclase of rat pineal gland by norepinephrine and sodium fluoride.

1969 • 77 citations

Influence of acute and chronic treatment with desmethylimipramine on catecholamine effects in the rat.

1978 • 76 citations

Chronic treatment with desipramine caused a sustained decrease of 3,4-dihydroxyphenylglycol-sulphate and total 3-methoxy-4-hydroxyphenylglycol in the rat brain

1977 • 74 citations

Convenient elimination of trichloroacetic acid prior to radioimmunoassay of cyclic nucleotides

1977 • 66 citations

MODE OF ACTION OF IMIPRAMINE ANID 5-(3'-METHYLAMINOPROPYLIDEN)-DIBENZO[a,e]CYCLOHEPTA[1,3,5]TRIEN HYDROCHLORIDE (RO 4-6011), A NEW ANTIDEPRESSANT DRUG, ON PERIPHERAL ADRENERGIC MECHANISMS

1964 • 52 citations

Decrease in brain NE turnover after chronic DMI treatment; no effect with iprindole

1978 • 42 citations

Do tricyclic antidepressants enhance adrenergic transmission?

1977 • 37 citations

Radioimmunoassay of imipramine and desmethylimipramine

1978 • 36 citations

Desipramine and some other antidepressant drugs decrease the major norepinephrine metabolite 3,4-dihydroxyphenylglycol-sulphate in the rat brain

1977 • 34 citations

In Vivo Inactivation of Catecholamines in Mice

1963 • 23 citations

Increase caused by desmethylimipramine in the production of [3H]melatonin by isolated pineal glands

1977 • 22 citations