Animal models for the study of milk secretion

Partitioning of Nutrients During Pregnancy and Lactation: A Review of Mechanisms Involving Homeostasis and Homeorhesis

1980 • 1,772 citations

The physiology of reproduction

1973 • 683 citations

Maternal Rescue of Transforming Growth Factor-β 1 Null Mice

1994 • 494 citations

Reversible Inhibition of Mammary Gland Growth by Transforming Growth Factor-β

1987 • 408 citations

Bovine Somatotropin: Review of an Emerging Animal Technology

1992 • 349 citations

Progress in prolactin physiology and pathology

1978 • 277 citations

Alteration of the quality of milk by expression of sheep β-lactoglobulin in transgenic mice

1987 • 273 citations

Regulated expression and growth inhibitory effects of transforming growth factor-β isoforms in mouse mammary gland development

1991 • 228 citations

Targeting expression of a transforming growth factor beta 1 transgene to the pregnant mammary gland inhibits alveolar development and lactation.

1993 • 224 citations

Autocrine regulation of milk secretion by a protein in milk

1995 • 215 citations

Cloning and in vivo expression of bovine growth hormone receptor mRNA

1990 • 195 citations

Prolactin Regulation of Milk Secretion and Biochemical Differentiation of Mammary Epithelial Cells in Periparturient Cows*

1981 • 182 citations

TGF-β1-induced inhibition of mouse mammary ductal growth: Developmental specificity and characterization

1989 • 174 citations

Progestin-induced growth hormone excess in the dog originates in the mammary gland.

1994 • 161 citations

Creation and phenotypic analysis of alpha-lactalbumin-deficient mice.

1994 • 147 citations

High-level synthesis of a heterologous milk protein in the mammary glands of transgenic swine.

1991 • 147 citations

The effects of oxytocin and milk removal on milk secretion in the goat

1971 • 133 citations

PROLACTIN RELEASE IN CATTLE

1974 • 128 citations

Increase in milk secretion and mammary blood flow by intra-arterial infusion of insulin-like growth factor-I into the mammary gland of the goat

1990 • 127 citations

The Nature and Regulation of the Receptors for Pituitary Growth Hormone

1985 • 122 citations

Intact and amino-terminally shortened forms of insulin-like growth factor I induce mammary gland differentiation and development.

1992 • 114 citations

The short‐term synthesis and infant‐regulated removal of milk in lactating women

1993 • 114 citations

Milk accumulation and distribution in the bovine udder during the interval between milkings

1994 • 113 citations

Lactation is disrupted by alpha-lactalbumin deficiency and can be restored by human alpha-lactalbumin gene replacement in mice.

1995 • 112 citations

Evidence that the growth hormone receptor mediates differentiation and development of the mammary gland.

1993 • 110 citations

Evidence that growth hormone stimulates milk synthesis by direct action on the mammary gland and that prolactin exerts effects on milk secretion by maintenance of mammary deoxyribonucleic acid content and tight junction status.

1994 • 109 citations

Bovine lactoferrin mRNA: Sequence, analysis, and expression in the mammary gland

1991 • 105 citations

NON-LACTOGENIC EFFECTS OF GROWTH HORMONE ON GROWTH AND INSULIN-LIKE GROWTH FACTOR-I MESSENGER RIBONUCLEIC ACID OF RAT MAMMARY GLAND

1990 • 105 citations

Effects of Long-Term Thrice-Daily Milking on Mammary Enzyme Activity, Cell Population and Milk Yield in the Goat1

1987 • 102 citations

Effect of exogenous prolactin administration on lactational performance of dairy cows

1987 • 96 citations

The role of growth hormone, prolactin and insulin-like growth factors in the regulation of rat mammary gland and adipose tissue metabolism during lactation

1992 • 96 citations

THE MAINTENANCE OF LACTATION IN THE RABBIT AFTER HYPOPHYSECTOMY

1969 • 96 citations

Once daliy milking of dairy cows: relationship between yield loss and cisternal milk storage

1994 • 92 citations

TGF beta suppresses casein synthesis in mouse mammary explants and may play a role in controlling milk levels during pregnancy.

1993 • 90 citations

Milk composition and lactation of beta-casein-deficient mice.

1994 • 89 citations

Galactopoietic and mammogenic effects of long-term treatment with bovine growth hormone and thrice daily milking in goats

1990 • 85 citations

Effects of 2-Br-α-ergocryptine on plasma prolactin level and milk yield in cows

1972 • 79 citations

EFFECT OF 2-BROMO-α-ERGOCRYPTINE ON MILK YIELD AND THE LEVEL OF PROLACTIN AND GROWTH HORMONE IN THE BLOOD OF THE GOAT AT MILKING

1973 • 74 citations

Galactopoietic Activity of Purified Anterior Pituitary Growth Hormone

1949 • 72 citations

Bovine Serum Prolactin, Growth Hormone, Cortisol and Milk Yield after Ergocryptine

1974 • 69 citations

Milk yield and mammary function in goats during and after once-daily milking

1990 • 68 citations

Transcription of prolactin gene in milk secretory cells of the rat mammary gland

1993 • 67 citations

Role of growth hormone and insulin-like growth factor-I in mammary development.

1993 • 66 citations

Feed‐back control of milk secretion in the goat by a chemical in milk.

1984 • 65 citations

Inhibition of Lactation and Prolactin Secretion in Rats by Ergot Alkaloids

1972 • 60 citations

Growth Hormone-Releasing Factor Stimulates Milk Production and Sustains Growth Hormone Release in Holstein Cows

1986 • 58 citations

Regulation of bovine mammary growth by peptide hormones: involvement of receptors, growth factors and binding proteins

1993 • 57 citations

Effects of 2-Br-α-ergokryptine on plasma prolactin level during parturition and onset of lactation in cows

1972 • 57 citations

Ligand-specific dimerization of the extracellular domain of the bovine growth hormone receptor.

1993 • 56 citations

Local regulation of mammary apoptosis in the lactating goat

1994 • 54 citations

Distribution of milk in the goat mammary gland and its relation to the rate and control of milk secretion

1988 • 54 citations

Investigation of the mechanism of action of growth hormone in stimulating lactation in the rat

1992 • 51 citations

Evidence for a Steady Rate of Secretion of Prolactin Following Suckling in the Rat

1974 • 49 citations

Separate and additive stimulation of bovine milk yield by the local and systemic galactopoietic stimuli of frequent milking and growth hormone

1992 • 48 citations

THE IMPORTANCE OF PROLACTIN FOR LACTATION IN THE EWE

1978 • 47 citations

Mechanisms Involved in the Adrenalin-Induced Blockade of Milk Ejection in Dairy Cattle

1985 • 46 citations

EFFECTS OF BROMOCRIPTINE ON MILK SECRETION IN THE RABBIT

1975 • 44 citations

EFFECTS OF REMOVING MILK FROM THE MAMMARY DUCTS AND ALVEOLI, OR OF DILUTING STORED MILK, ON THE RATE OF MILK SECRETION IN THE GOAT

1987 • 44 citations

Stimulation of Milk Yield and Feed Intake by Bovine Placental Lactogen in the Dairy Cow

1992 • 43 citations

Effects of an antiserum to rat growth hormone on lactation in the rat

1986 • 42 citations

Lactational Performance of Rats Injected with Oxytocin, Cortisol-21-acetate, Prolactin and Growth Hormone During Prolonged Lactation

1970 • 37 citations

HORMONALLY-INDUCED LACTATION IN HYPOPHYSECTOMIZED RATS¹

1958 • 37 citations

THE EFFECTS OF MILKING THRICE INSTEAD OF TWICE DAILY ON MILK SECRETION IN THE GOAT

1983 • 37 citations

COMPLETE RESTORATION OF LACTATION IN THE GOAT AFTER HYPOPHYSECTOMY

1964 • 36 citations

Milking frequency alters the milk yield and mammary blood flow response to intra-mammary infusion of insulin-like growth factor-I in the goat

1992 • 35 citations

Effects of Infusions of Various Doses of Bovine Growth Hormone-Releasing Factor on Growth Hormone and Lactation in Holstein Cows

1988 • 35 citations

Mammary tumorigenesis and chemoprevention studies in carcinogen-treated rats

1996 • 35 citations

EFFECTS OF ADMINISTERING ANTISERA TO MOUSE GROWTH HORMONE AND PROLACTIN ON GAIN IN LITTER WEIGHT AND ON MAMMARY NUCLEIC ACID CONTENT OF LACTATING C3H MICE

1972 • 34 citations

Relaxin Detected by Immunocytochemistry and Northern Analysis in the Mammary Gland of the Guinea Pig*

1989 • 34 citations

Comparison of Somatotropin and Growth Hormone-Releasing, Factor on Milk Yield, Serum Hormones, and Energy Status

1991 • 34 citations

Effect of Human Growth Hormone-releasing Factor (1–29)NH2 on Growth Hormone Release and Milk Production in Dairy Cows

1988 • 34 citations

Effects of prolactin, progesterone and ovariectomy on metabolic activities and insulin receptors in the mammary gland and adipose tissue during extended lactation in the rat

1984 • 33 citations

In VivoEffects of Antisera to Prolactin Receptors in Female Rats*

1978 • 32 citations

Local control of parathyroid hormone-related protein secretion by the mammary gland of the goat

1994 • 31 citations

Mammary Arterial and Venous Concentrations of Prolactin in Lactating Cows after Milking or Administration of Thyrotropin-Releasing Hormone or Ergocryptine*

1979 • 29 citations

Several insulin-like growth factor-I analogues and complexes of insulin-like growth factors-I and -II with insulin-like growth factor-binding protein-3 fail to mimic the effect of growth hormone upon lactation in the rat

1994 • 29 citations

Relationship between milk storage characteristics and the short-term response of dairy cows to thrice-daily milking

1994 • 29 citations

Metabolic adaptations in goat mammary tissue during long-term incomplete milking

1989 • 29 citations

Effects of CB154 on serum hormone level and lactogenesis in dairy cows.

1978 • 27 citations

Production Responses of Cows to Recombinantly Derived Bovine Somatotropin and to Frequency of Milking

1994 • 26 citations

Transforming growth factor-β1 inhibits casein secretion from differentiating mammary-gland explants but not from lactating mammary cells

1994 • 25 citations

Milk yield responses to sequential treatments with recombinant bovine somatotrophin and frequent milking in lactating goats

1992 • 25 citations

Sixty-Day Infusions of Somatotropin-Releasing Factor Stimulate Milk Production in Dairy Cows

1990 • 25 citations

Active immunization of pigs against growth hormone-releasing factor: effect on concentrations of growth hormone and insulin-like growth factor 1.

1990 • 24 citations

Galactopoietic Effects of Recombinant Somatotropin and Growth Hormone-Releasing Factor in Dairy Cows

1993 • 21 citations

Effects of Ergot Drugs on Prolactin and Growth Hormone Secretion, and on Mammary Nucleic Acid Content in C3H/Bi Mice2

1974 • 20 citations

Prostaglandins and lactation.

1981 • 18 citations

β-Adrenergic blockade counteracts starvational ketosis, but aggravates post-exercise ketosis in non-athletes

1988 • 17 citations

Location of an epitope defined by an enhancing monoclonal antibody to growth hormone: some structural details and biological implications.

1994 • 17 citations

SYNTHESIS OF LACTOFERRIN AND CASEIN BY EXPLANTS OF BOVINE MAMMARY TISSUE

1994 • 16 citations

Decrease in litter weight gain and in progesterone secretion in lactating rats treated with antiserum to rat prolactin

1976 • 16 citations

Effect of active immunization against growth hormone releasing factor on concentrations of somatotropin and insulin-like growth factor I in lactating beef cows

1992 • 15 citations

Effect of Increased Postmilking Prolactin Concentrations on Lactation, Plasma Metabolites, and Pancreatic Hormones in Lactating Goats

1991 • 15 citations

Growth Hormone-Releasing Factor Effects on Pituitary Function, Growth, and Lactation

1987 • 14 citations

PITUITARY GRAFTS AND MILK SECRETION IN HYPOPHYSECTOMIZED RATS

1960 • 14 citations

THE MAINTENANCE OF LACTATION IN THE GOAT AFTER HYPOPHYSECTOMY

1961 • 14 citations

THE MAINTENANCE OF LACTATION IN THE RAT AFTER HYPOPHYSECTOMY

1957 • 13 citations

Effects of immunization against an autocrine inhibitor of milk secretion in lactating goats.

1996 • 13 citations

An Object-Oriented Model for Simulating Milking Parlor Operations

1994 • 13 citations

Effect of a fraction of goat milk serum proteins on milk accumulation and enzyme activities in rabbit mammary gland

1987 • 13 citations

THE EFFECT OF ERGOTAMINE AND DIHYDROERGOTAMINE ON LACTATION IN THE RAT

1956 • 12 citations

Effect of Ergotamine on Milk-Ejection in Lactating Rat.

1956 • 11 citations

HYPOPHYSECTOMY OF THE GOAT

1961 • 11 citations

Immunization against somatotropin release inhibiting factor increases milk yield in ewes

1990 • 11 citations

Effect of Graded Levels of Lactogenic Hormone upon Mammary Gland Growth and Lactation in Rats.

1966 • 11 citations

Local Control of Mammary Apoptosis by Milk Stasis

1995 • 10 citations

Effects of Growth Hormone on Lactation and Body Growth of Parturient Rats.

1957 • 6 citations

The effect of psychopharmacologic prolactin releasers on lactation in sheep.

1974 • 6 citations

Role of Bovine Placental Lactogen in Intercellular Signalling during Mammary Growth and Lactation

1995 • 6 citations

INFLUENCE OF THE SUPPRESSION OF THE PRE PARTUM SURGE OF PROLACTIN BY ERGOCRYPTIN ON THE MILK YIELD AND ON THE POST PARTUM ANOESTRUS OF THE NURSING EWE

1976 • 5 citations

Effect of 9-Fluoroprednisolone Acetate and Transplanted Pituitaries on Milk Synthesis

1970 • 5 citations

EFFECT OF ANTISERUM TO RAT PROLACTIN ON MILK YIELD AND FOOD INTAKE IN THE RAT

1975 • 5 citations

Local control of the onset of mammary extraction of plasma triglycerides during lactogenesis in the goat

1990 • 2 citations