Evidence that Hodgkin and Reed-Sternberg cells in Hodgkin disease do not represent cell fusions

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

1999 • 1,139 citations

[Hodgkin's disease].

1988 • 829 citations

Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells.

1996 • 749 citations

Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development.

1994 • 691 citations

Hodgkin and Reed-Sternberg cells represent an expansion of a single clone originating from a germinal center B-cell with functional immunoglobulin gene rearrangements but defective immunoglobulin transcription

2000 • 493 citations

High Expression of the CC Chemokine TARC in Reed-Sternberg Cells

1999 • 379 citations

THE ORIGIN OF HODGKIN AND REED/STERNBERG CELLS IN HODGKIN'S DISEASE

1998 • 314 citations

Identification of Common Germinal-Center B-Cell Precursors in Two Patients with Both Hodgkin's Disease and Non-Hodgkin's Lymphoma

1999 • 264 citations

Rare Occurrence of Classical Hodgkin's Disease as a T Cell Lymphoma

2000 • 217 citations

Detection of clonal T-cell receptor gamma-chain gene rearrangements in Reed-Sternberg cells of classic Hodgkin disease

2000 • 214 citations

Numerical chromosome aberrations are present within the CD30+ Hodgkin and Reed-Sternberg cells in 100% of analyzed cases of Hodgkin's disease [see comments]

1995 • 153 citations

Recent Results on the Biology of Hodgkin and Reed-Sternberg Cells. I. Biopsy Material

1992 • 145 citations

Hodgkin and Reed-Sternberg–like cells in B-cell chronic lymphocytic leukemia represent the outgrowth of single germinal-center B-cell–derived clones: potential precursors of Hodgkin and Reed-Sternberg cells in Hodgkin's disease

2000 • 135 citations

Expression Status of BCL-6 and Syndecan-1 Identifies Distinct Histogenetic Subtypes of Hodgkin's Disease

1998 • 134 citations

A deletion map of the human immunoglobulin heavy chain variable region.

1991 • 51 citations

Amplification of TCRβ gene rearrangements from micromanipulated single cells: T cells rosetting around Hodgkin and Reed-Sternberg cells in Hodgkin's disease are polyclonal

1998 • 50 citations

Expression of the LMP1 oncoprotein in the EBV negative Hodgkin's disease cell line L-428 is associated with Reed-Sternberg cell morphology.

1996 • 42 citations

Cytogenetics of Hodgkin’s disease

1998 • 39 citations

Molecular single-cell analysis of the clonal relationship of small Epstein-Barr virus–infected cells and Epstein-Barr virus–harboring Hodgkin and Reed/Sternberg cells in Hodgkin disease

2000 • 35 citations

Hodgkin's disease: The sternberg-reed cell

1987 • 20 citations

Giant cell formation in Hodgkin's disease

1994 • 11 citations

The origins of Hodgkinʼs disease

1995 • 9 citations

Numerical chromosomal aberrations in Hodgkin's disease detected by in situ hybridisation on routine paraffin sections.

1997 • 7 citations