Herpes Simplex Virus Inhibitor ICP47 Destabilizes the Transporter Associated with Antigen Processing (TAP) Heterodimer

ABC Transporters: From Microorganisms to Man

1992 • 3,956 citations

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

Identification of self peptides bound to purified HLA-B27

1991 • 844 citations

Herpes simplex virus turns off the TAP to evade host immunity

1995 • 736 citations

Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters

1990 • 717 citations

Roles for Calreticulin and a Novel Glycoprotein, Tapasin, in the Interaction of MHC Class I Molecules with TAP

1996 • 697 citations

A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway

1990 • 644 citations

CYTOLOGY OF BURKITT'S TUMOUR (AFRICAN LYMPHOMA)

1964 • 627 citations

A viral inhibitor of peptide transporters for antigen presentation

1995 • 599 citations

A Critical Role for Tapasin in the Assembly and Function of Multimeric MHC Class I-TAP Complexes

1997 • 528 citations

Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells.

1989 • 443 citations

The Cystic Fibrosis Transmembrane Conductance Regulator

1993 • 438 citations

Transport Protein Genes in the Murine MHC: Possible Implications for Antigen Processing

1990 • 438 citations

MHC class II region encoding proteins related to the muKidrug resistance family of transmembrane transporters

1990 • 426 citations

MHC class l/β2-microglobulin complexes associate with TAP transporters before peptide binding

1994 • 356 citations

Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47.

1996 • 350 citations

Interaction of MHC Class I Molecules with the Transporter Associated with Antigen Processing

1994 • 300 citations

Soluble Tapasin Restores MHC Class I Expression and Function in the Tapasin-Negative Cell Line .220

1998 • 298 citations

A sequential model for peptide binding and transport by the transporters associated with antigen processing

1994 • 290 citations

Stable binding of the herpes simplex virus ICP47 protein to the peptide binding site of TAP.

1996 • 271 citations

Evidence that transporters associated with antigen processing translocate a major histocompatibility complex class I-binding peptide into the endoplasmic reticulum in an ATP-dependent manner.

1993 • 266 citations

Functional expression and purification of the ABC transporter complex associated with antigen processing (TAP) in insect cells

1994 • 201 citations

Dependence of Peptide Binding by MHC Class I Molecules on Their Interaction with TAP

1995 • 189 citations

Mutations that impair a posttranscriptional step in expression of HLA-A and -B antigens.

1985 • 183 citations

Human transporters associated with antigen processing possess a promiscuous peptide-binding site

1994 • 178 citations

The Active Site of ICP47, a Herpes Simplex Virus–encoded Inhibitor of the Major Histocompatibility Complex (MHC)-encoded Peptide Transporter Associated with Antigen Processing (TAP), Maps to the NH2-terminal 35 Residues

1997 • 169 citations

Characteristics of peptide and major histocompatibility complex class I/beta 2-microglobulin binding to the transporters associated with antigen processing (TAP1 and TAP2).

1994 • 150 citations

Mapping the fine specificity of a cytolytic T cell response to HIV-1 nef protein.

1990 • 133 citations

Cloning and functional characterization of a subunit of the transporter associated with antigen processing

1997 • 127 citations

MHC class I expression and transport in a calnexin-deficient cell line.

1995 • 108 citations

The active domain of the herpes simplex virus protein ICP47: A potent inhibitor of the transporter associated with antigen processing (TAP)

1997 • 88 citations

Rescue of Daudi cell HLA expression by transfection of the mouse beta 2-microglobulin gene.

1988 • 79 citations

Reconstitution of peptide‐binding activity by TAP in proteoliposomes

1997 • 5 citations