HLA Class I Expression on the Materno‐Fetal Interface

A Class I Antigen, HLA-G, Expressed in Human Trophoblasts

1990 • 1,417 citations

Granulated lymphocytes in human endometrium: histochemical and immunohistochemical studies

1991 • 550 citations

Alternative splicing of HLA-G transcripts yields proteins with primary structures resembling both class I and class II antigens.

1992 • 515 citations

Human placental HLA-G expression is restricted to differentiated cytotrophoblasts.

1995 • 479 citations

Nature of polymorphism in HLA-A, -B, and -C molecules.

1988 • 379 citations

Pathology of the Human Placenta

1995 • 378 citations

A soluble form of the HLA-G antigen is encoded by a messenger ribonucleic acid containing intron 4.

1994 • 365 citations

The membrane-bound and soluble forms of HLA-G bind identical sets of endogenous peptides but differ with respect to TAP association

1995 • 320 citations

Evidence for the expression of HLAA-C class I mRNA and protein by human first trimester trophoblast.

1996 • 259 citations

HLA-E. A novel HLA class I gene expressed in resting T lymphocytes.

1988 • 239 citations

Early human decidual cells exhibit NK activity against the K562 cell line but not against first trimester trophoblast

1989 • 233 citations

An alternatively spliced form of HLA-G mRNA in human trophoblasts and evidence for the presence of HLA-G transcript in adult lymphocytes.

1994 • 230 citations

Differential expression of HLA-E, HLA-F, and HLA-G transcripts in human tissue

1990 • 224 citations

Resistance of HLA-G and HLA-A2 Transfectants to Lysis by Decidual NK Cells

1994 • 179 citations

Interaction between major histocompatibility complex antigens and epidermal growth factor receptors on human cells.

1984 • 176 citations

The human amnion is a site of MHC class Ib expression: evidence for the expression of HLA-E and HLA-G.

1995 • 171 citations

Differentiation and proliferation patterns in human trophoblast revealed by c-erbB-2 oncogene product and EGF-R.

1993 • 160 citations

The major histocompatibility complex class I heavy chain as a structural subunit of the human cell membrane insulin receptor: implications for the range of biological functions of histocompatibility antigens.

1986 • 153 citations

Analysis of HLA-G mRNA in human placental and extraplacental membrane cells by in situ hybridization.

1991 • 144 citations

Cell-cell adhesion mediated by CD8 and human histocompatibility leukocyte antigen G, a nonclassical major histocompatibility complex class 1 molecule on cytotrophoblasts.

1991 • 128 citations

HLA Class I Chromosomal Region, Genes, and Products: Facts and Questions

1994 • 123 citations

HLA-G revisited

1996 • 112 citations

The HLA-G gene is expressed at a low mRNA level in different human cells and tissues

1994 • 108 citations

Amnion Epithelial Cells, in Contrast to Trophoblast Cells, Express All Classical HLA Class I Molecules Together With HLA‐G

1997 • 107 citations

HLA-G polymorphisms in African Americans.

1994 • 105 citations

Polymorphism at the HLA-E locus predates most HLA-A and -B polymorphism

1992 • 102 citations

Soluble HLA-G molecule

1995 • 94 citations

Expression of HLA class I molecules in human first trimester and term placenta trophoblast

1996 • 93 citations

The MHC E locus in macaques is polymorphic and is conserved between macaques and humans

1995 • 90 citations

Molecular association between major histocompatibility complex class I antigens and insulin receptors in mouse liver membranes.

1985 • 87 citations

Expression of class I HLA genes by trophoblast cells. Analysis by in situ hybridization.

1988 • 86 citations

Cytotoxic activity against trophoblast and choriocarcinoma cells of large granular lymphocytes from human early pregnancy decidua

1991 • 84 citations

Reciprocal expression of epidermal growth factor receptor (EGF-R) and c-erbB2 by non-invasive and invasive human trophoblast populations

1994 • 83 citations

Methylation status and transcriptional expression of the MHC class I loci in human trophoblast cells from term placenta.

1995 • 83 citations

The mRNA of a human class I gene HLA G/HLA 6.0 exhibits a restricted pattern of expression

1990 • 80 citations

Evidence for the expression of non-HLA-A,-B,-C class I genes in the human fetal liver.

1992 • 77 citations

Regulation of insulin receptor functions by a peptide derived from a major histocompatibility complex class I antigen

1990 • 73 citations

In situ hybridization and northern blot demonstration of HLA-G mRNA in human trophoblast populations by locus-specific oligonucleotide

1993 • 70 citations

Placental Expression of HLA Class I Genes

1996 • 69 citations

Recent developments in the human maternal-fetal immune interaction

1991 • 64 citations

HLA-E is the only class I gene that escapes CpG methylation and is transcriptionally active in the trophoblast-derived human cell line JAR

1993 • 64 citations

Antigenic heterogeneity of human cytotrophoblast and evidence for the transient expression of MHC class I antigens distinct from HLA-G

1993 • 63 citations

Identification of class I MHC mRNA in human first trimester trophoblast cells by in situ hybridization.

1990 • 61 citations

Generation of an antibody to HLA-G in transgenic mice and demonstration of the tissue reactivity of this antibody

1994 • 57 citations

HLA‐G: expression in human keratinocytes in vitro and in human skin in vivo

1994 • 51 citations

Molecular and biological interaction between major histocompatibility complex class I antigens and luteinizing hormone receptors or beta-adrenergic receptors triggers cellular response in mice.

1988 • 47 citations

Human decidual leukocytes do not proliferate in response to either extravillous trophoblast or allogeneic peripheral blood lymphocytes

1996 • 33 citations

Regulation of receptor internalization by the major histocompatibility complex class I molecule.

1994 • 22 citations

Detection of class I MHC mRNA in subpopulations of first trimester cytotrophoblast cells by in situ hybridization

1991 • 20 citations

A set of antibodies which specifically bind alternative HLA-G proteins distinguish HLA-G expression in vivo

1996 • 3 citations

Soluble HLA class I molecules induce apoptosis in human PHA-activated CD8+ T lymphocytes

1996 • 2 citations

Interferoy-γ rescues HLA class Ia cell surface expression in term villous trophoblast cells by inducing synthesis of TAP proteins

1996 • 1 citations