Placental Expression of HLA Class I Genes

A Class I Antigen, HLA-G, Expressed in Human Trophoblasts

1990 • 1,417 citations

Recognition of a lipid antigen by CD1-restricted αβ+ T cells

1994 • 976 citations

Alternative splicing of HLA-G transcripts yields proteins with primary structures resembling both class I and class II antigens.

1992 • 515 citations

Human placental HLA-G expression is restricted to differentiated cytotrophoblasts.

1995 • 479 citations

A soluble form of the HLA-G antigen is encoded by a messenger ribonucleic acid containing intron 4.

1994 • 365 citations

Regulation of MHC Class I Transport by the Molecular Chaperone, Calnexin (p88, IP90)

1994 • 351 citations

DNA methylation and genomic imprinting

1994 • 349 citations

?Both man & bird & beast?: comparative organization of MHC genes

1995 • 307 citations

The Role of Cytokines in Gestation

1994 • 254 citations

An alternatively spliced form of HLA-G mRNA in human trophoblasts and evidence for the presence of HLA-G transcript in adult lymphocytes.

1994 • 230 citations

Differential expression of HLA-E, HLA-F, and HLA-G transcripts in human tissue

1990 • 224 citations

Secretion of HLA-A and -B antigens via an alternative RNA splicing pathway.

1986 • 220 citations

Immunoregulation and Fetal Survival

1987 • 214 citations

The human amnion is a site of MHC class Ib expression: evidence for the expression of HLA-E and HLA-G.

1995 • 171 citations

Role of beta2-microglobulin in the intracellular transport and surface expression of murine class I histocompatibility molecules

1989 • 153 citations

The physiology of reproduction

1922 • 143 citations

HLA Class I Chromosomal Region, Genes, and Products: Facts and Questions

1994 • 123 citations

Intracellular transport of class I MHC molecules in antigen processing mutant cell lines.

1993 • 116 citations

Role of beta 2-microglobulin in the intracellular transport and surface expression of murine class I histocompatibility molecules.

1989 • 108 citations

The HLA-G gene is expressed at a low mRNA level in different human cells and tissues

1994 • 108 citations

HLA-G polymorphisms in African Americans.

1994 • 105 citations

Analysis of beta 2-microglobulin gene expression in the developing mouse embryo and placenta.

1990 • 96 citations

An unstable beta 2-microglobulin: major histocompatibility complex class I heavy chain intermediate dissociates from calnexin and then is stabilized by binding peptide.

1994 • 93 citations

The MHC E locus in macaques is polymorphic and is conserved between macaques and humans

1995 • 90 citations

Regulation of the β-globin locus

1993 • 88 citations

Methylation status and transcriptional expression of the MHC class I loci in human trophoblast cells from term placenta.

1995 • 83 citations

Immunobiology of pregnancy

1992 • 73 citations

Recent developments in the human maternal-fetal immune interaction

1991 • 64 citations

HLA-E is the only class I gene that escapes CpG methylation and is transcriptionally active in the trophoblast-derived human cell line JAR

1993 • 64 citations

Antigen presentation by non-classical class I molecules

1994 • 64 citations

Biochemical characterization of 39-kDa class I histocompatibility antigen in plasma. A secretable membrane protein derived from transmembrane domain deletion

1991 • 63 citations

Extraembryonic expression of the human MHC class I gene HLA-G in transgenic mice. Evidence for a positive regulatory region located 1 kilobase 5' to the start site of transcription.

1993 • 61 citations

Impaired intracellular transport and cell surface expression of nonpolymorphic HLA-E: evidence for inefficient peptide binding.

1992 • 61 citations

Generation of an antibody to HLA-G in transgenic mice and demonstration of the tissue reactivity of this antibody

1994 • 57 citations

MHC class I surface expression in embryo-derived cell lines inducible with peptide or interferon

1991 • 54 citations

HLA antigen expression and induction by γ-interferon in cultured human trophoblasts

1987 • 52 citations

Detection of membrane-bound HLA-G translated products with a specific monoclonal antibody.

1995 • 43 citations

Alternative splicing generates secretory isoforms of human CD1.

1994 • 41 citations

Paternal and maternal major histocompatibility complex class I antigens are expressed co-dominantly by equine trophoblast

1994 • 38 citations

Localization of major histocompatibility complex class I and II mRNA in human first-trimester chorionic villi by in situ hybridization.

1992 • 32 citations

Expression of TAP1 by human trophoblast

1995 • 28 citations

Altered regulation of MHC class I genes in different tumor cell lines is reflected by distinct sets of DNase I hypersensitive sites.

1989 • 28 citations

Lack of expression of HLA-B27 gene in transgenic mouse trophoblast. Conserved genetic pressures underlying extra-embryonic development.

1989 • 26 citations

Purification of human cytotrophoblast from term amniochorion by flow cytometry

1990 • 25 citations

Amnion membrane epithelial cells express class I HLA and contain class I HLA mRNA.

1988 • 23 citations

Expression of HLA class II-associated peptide transporter and proteasome genes in human placentas and trophoblast cell lines.

1994 • 22 citations

A defect in the presentation of intracellular viral antigens is restored by interferon‐γ in cell lines with impaired major histocompatibility complex class I assembly

1992 • 19 citations

Differential nuclear expression of enhancer A DNA-binding proteins in human first trimester trophoblast cells.

1993 • 19 citations

Nuclear Regulation of HLA Class I Genes in Human Trophoblasts

1994 • 18 citations

Evolution of class I Promoter Sequences: Relationship to Function and Diversity

1995 • 17 citations

Transfected trophoblast‐derived human cells can express a single HLA class I allelic product

1991 • 16 citations

Major Histocompatibility Complex Class I Molecules and Resistance against Intracellular Pathogens

1994 • 15 citations

Biogenesis of MHC class I antigens: involvement of multiple chaperone molecules.

1994 • 14 citations

Expression of HLA class I and β2-microglobulin on human choriocarcinoma cell lines: Induction of HLA class I by interferon-γ

1991 • 12 citations

MHC class I genes are not imprinted in the mouse placenta

1994 • 11 citations

Differences Between Human Sperm and Somatic Cell DNA in CpG Methylation Within the HLA Class I Chromosomal Region

1993 • 10 citations

Overexpression of Class I MHC in Murine Trophoblast and Increased Rates of Spontaneous Abortion

1994 • 8 citations

Transcription of HLA-G transgenes commences shortly after implantation during embryonic development in mice.

1994 • 8 citations

Immune Control of Pregnancy

1994 • 4 citations