Induction of specific T-cell responses in HIV infection

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1995 • 4,310 citations

Identification of a major co-receptor for primary isolates of HIV-1

1996 • 3,649 citations

HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time

1996 • 3,496 citations

Viral dynamics in human immunodeficiency virus type 1 infection

1995 • 3,277 citations

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

1996 • 3,189 citations

Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8 ⁺ T Cells

1995 • 2,890 citations

Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

1996 • 2,883 citations

The role of a mutant CCR5 allele in HIV–1 transmission and disease progression

1996 • 1,364 citations

The Th1–Th2 hypothesis of HIV infection: new insights

1994 • 708 citations

Molecular Cloning and Functional Expression of a New Human CC-Chemokine Receptor Gene

1996 • 701 citations

Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell numbers and clinical staging.

1989 • 637 citations

A Short-Term Study of the Safety, Pharmacokinetics, and Efficacy of Ritonavir, an Inhibitor of HIV-1 Protease

1995 • 569 citations

A Preliminary Study of Ritonavir, an Inhibitor of HIV-1 Protease, to Treat HIV-1 Infection

1995 • 484 citations

Preferential infection of CD4+ memory T cells by human immunodeficiency virus type 1: evidence for a role in the selective T-cell functional defects observed in infected individuals.

1990 • 443 citations

Effect of Immunization with a Common Recall Antigen on Viral Expression in Patients Infected with Human Immunodeficiency Virus Type 1

1996 • 379 citations

A Phase I Evaluation of the Safety and Immunogenicity of Vaccination with Recombinant gp160 in Patients with Early Human Immunodeficiency Virus Infection

1991 • 248 citations

Heterozygosity for a deletion in the CKR-5 gene leads to prolonged AIDS-free survival and slower CD4 T-cell decline in a cohort of HIV-seropositive individuals

1997 • 238 citations

Characteristics of the specific cell-mediated immune response in human immunodeficiency virus infection

1987 • 177 citations

Inhibition of functional properties of tetanus antigen-specific T-cell clones by envelope glycoprotein GP120 of human immunodeficiency virus

1990 • 112 citations

Loss of Inducible Virus in CD45RA Naive Cells After Human Immunodeficiency Virus-1 Entry Accounts for Preferential Viral Replication in CD45RO Memory Cells

1997 • 88 citations

Serum chemokine levels in patients with non-progressing HIV infection

1996 • 84 citations

Randomised trial of MNrgp120 HIV-1 vaccine in symptomless HIV-1 infection

1996 • 71 citations

Initial Studies on Active Immunization of HIV-Infected Subjects Using a gp120-Depleted HIV-1 Immunogen: Long-Term Follow-Up

1996 • 59 citations

Enhancement of human immunodeficiency virus (HIV)-specific CD4+ and CD8+ cytotoxic T-lymphocyte activities in HIV-infected asymptomatic patients given recombinant gp160 vaccine.

1992 • 54 citations

Human Immunodeficiency Virus (HIV-l) gp160-Specific Lymphocyte Proliferative Responses of Mononuclear Leukocytes from HIV-l Recombinant gp160 Vaccine Recipients

1991 • 43 citations

Immunization with subunit human immunodeficiency virus vaccine generates stronger T helper cell immunity than natural infection

1991 • 43 citations

Improved cell-mediated immune responses in HIV-1-infected asymptomatic individuals after immunization with envelope glycoprotein gp160.

1994 • 43 citations

HIV infection leads to differential expression of T-cell receptor Vβ genes in CD4+ and CD8+ T cells

1993 • 42 citations

Lymphocyte proliferative responses following immunization with human immunodeficiency virus recombinant GP160

1992 • 38 citations

Assessments of Plasma HIV RNA and CD4 Cell Counts after Combined Pneumovax® and Tetanus Toxoid Vaccination: No Detectable Increase in HIV Replication 6 Weeks after Immunization

1996 • 31 citations

Impaired proliferative capacity and abnormal cytokine profile of naive and memory CD4 T cells from HIV-seropositive patients

1992 • 30 citations

HIV-Specific Vaccine Therapy: Concepts, Status, and Future Directions

1992 • 28 citations

Lymphoproliferative Responses to Mitogens and HIV-1 Envelope Glycoprotein Among Volunteers Vaccinated with Recombinant gp160

1990 • 27 citations

Markedly disturbed glutathione redox status in CD45RA+CD4+ lymphocytes in human immunodeficiency virus type 1 infection is associated with selective depletion of this lymphocyte subset

1996 • 23 citations

The influence of MT-2 tropism on the prognostic implications of the Δ32 deletion in the CCR-5 gene

1997 • 20 citations

Virology

1996 • 11 citations

Evidence for an in vivo superantigenic activity in human immunodeficiency virus-infected individuals

1996 • 10 citations

Effect of a Recombinant CD4-IgG on In Vitro T Helper Cell Function: Data from a Phase I/II Study of Patients with AIDS

1993 • 7 citations