A Phase I Evaluation of the Safety and Immunogenicity of Vaccination with Recombinant gp160 in Patients with Early Human Immunodeficiency Virus Infection

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Abnormalities of B-Cell Activation and Immunoregulation in Patients with the Acquired Immunodeficiency Syndrome

1983 • 1,625 citations

The Human Immunodeficiency Virus: Infectivity and Mechanisms of Pathogenesis

1988 • 1,496 citations

Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor

1987 • 827 citations

HIV-specific cytotoxic T lymphocytes in seropositive individuals

1987 • 797 citations

Qualitative Analysis of Immune Function in Patients with the Acquired Immunodeficiency Syndrome

1985 • 737 citations

The Risk ofPneumocystis cariniiPneumonia among Men Infected with Human Immunodeficiency Virus Type 1

1990 • 682 citations

Biologic Features of HIV-1 That Correlate with Virulence in the Host

1988 • 679 citations

Conserved Sequence and Structural Elements in the HIV-1 Principal Neutralizing Determinant

1990 • 665 citations

Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120.

1988 • 626 citations

REPLICATIVE CAPACITY OF HUMAN IMMUNODEFICIENCY VIRUS FROM PATIENTS WITH VARYING SEVERITY OF HIV INFECTION

1986 • 536 citations

A Prospective Study of Human Immunodeficiency Virus Type 1 Infection and the Development of AIDS in Subjects with Hemophilia

1989 • 536 citations

The Walter Reed Staging Classification for HTLV-III/LAV Infection

1986 • 523 citations

Neutralization of human T-lymphotropic virus type III by sera of AIDS and AIDS-risk patients

1985 • 448 citations

HTLV-III-neutralizing antibodies in patients with AIDS and AIDS-related complex

1985 • 427 citations

Defective Regulation of Epstein–Barr Virus Infection in Patients with Acquired Immunodeficiency Syndrome (AIDS) or AIDS-Related Disorders

1986 • 384 citations

Increasing Viral Burden in CD4+ T Cells from Patients with Human Immunodeficiency Virus (HIV) Infection Reflects Rapidly Progressive Immunosuppression and Clinical Disease

1990 • 281 citations

Long-Term Evaluation of HIV Antigen and Antibodies to p24 and gp41 in Patients with Hemophilia

1987 • 245 citations

Second Conserved Domain of gp120 Is Important for HIV Infectivity and Antibody Neutralization

1988 • 242 citations

Vaccination with Recombinant Herpes Simplex Virus Glycoproteins: Protection Against Initial and Recurrent Genital Herpes

1987 • 203 citations

The structure of medicine.

1948 • 200 citations

Early effects of HIV on CD4 lymphocytes in vivo.

1987 • 197 citations

Induction of interleukin-6 during human immunodeficiency virus infection

1990 • 191 citations

HIV Infection: The Clinical Picture

1988 • 172 citations

The Safety and Immunogenicity of a Human Immunodeficiency Virus Type 1 (HIV-1) Recombinant gp160 Candidate Vaccine in Humans

1991 • 170 citations

Diagnosis of AIDS by Using a 12-Amino Acid Peptide Representing an Immunodominant Epitope of the Human Immunodeficiency Virus

1987 • 166 citations

Long-Term Seropositivity for Human T-Lymphotropic Virus Type III in Homosexual Men Without the Acquired Immunodeficiency Syndrome: Development of Immunologic and Clinical Abnormalities

1986 • 164 citations

Quantitative infectivity assay for HIV-1 and -2

1988 • 163 citations

Prospects for the control of AIDS by immunizing seropositive individuals

1987 • 157 citations

Mysteries of HIV: challenges for therapy and prevention

1988 • 148 citations

Antigenic peptides recognized by T lymphocytes from AIDS viral envelope-immune humans

1988 • 146 citations

Anti-GP 120 Antibodies from HIV Seropositive Individuals Mediate Broadly Reactive Anti-HIV ADCC

1987 • 131 citations

Group-specific, major histocompatibility complex class I-restricted cytotoxic responses to human immunodeficiency virus 1 (HIV-1) envelope proteins by cloned peripheral blood T cells from an HIV-1-infected individual.

1988 • 129 citations

Neutralization of diverse HIV-1 strains by monoclonal antibodies raised against a gp41 synthetic peptide

1988 • 128 citations

CELLULAR ANTI-GP120 CYTOLYTIC REACTIVITIES IN HIV-1 SEROPOSITIVE INDIVIDUALS

1988 • 119 citations

Type-Restricted Neutralization of Molecular Clones of Human Immunodeficiency Virus

1988 • 115 citations

Induction of human immunodeficiency virus type 1 expression in chronically infected cells is associated primarily with a shift in RNA splicing patterns

1991 • 96 citations

Clinical Implications of Positive Tests for Antibodies to Human Immunodeficiency Virus Type 1 in Asymptomatic Blood Donors

1989 • 81 citations

Nonrandom development of immunologic abnormalities after infection with human immunodeficiency virus: implications for immunologic classification of the disease.

1987 • 77 citations

Characterization of GP120 binding to CD4 and an assay that measures ability of sera to inhibit this binding.

1988 • 61 citations

Detection of Antibodies to Human T-Cell Lymphotropic Virus-III (HTLV-III) with an Immunoassay Employing a Recombinant Escherichia coli-Derived Viral Antigenic Peptide

1985 • 57 citations

The N-terminal region of the human immunodeficiency virus envelope glycoprotein gp120 contains potential binding sites for CD4.

1990 • 40 citations

Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120

1988 • 36 citations

Patterns of Antibody Recognition of Selected Conserved Amino Acid Sequences from the HIV Envelope in Sera from Different Stages of HIV Infection

1989 • 36 citations

Department of army lymphocyte immunophenotyping quality assurance program

1989 • 35 citations

Isolation of HIV-1 from the blood of seropositive adults: patient stage of illness and sample inoculum size are major determinants of a positive culture. The Walter Reed Retroviral Research Group.

1990 • 26 citations

Immunologic parameters in early-stage HIV-seropositive subjects associated with vaccine responsiveness.

1991 • 23 citations

Clinical performance of a polymerase chain reaction testing algorithm for diagnosis of HIV‐1 infection in peripheral blood mononuclear cells

1991 • 21 citations

Shadow on the Land: The Epidemiology of HIV Infection

1987 • 5 citations