Topiramate Treatment Protects Blood-Brain Barrier Pericytes from Hyperglycemia-Induced Oxidative Damage in Diabetic Mice

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

2009 • 13,873 citations

Free radicals and antioxidants in normal physiological functions and human disease

2006 • 13,251 citations

Superoxide Dismutase

1969 • 12,578 citations

Biochemistry and molecular cell biology of diabetic complications

2001 • 8,707 citations

The Pathobiology of Diabetic Complications

2005 • 4,849 citations

Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

2001 • 4,399 citations

Reactive Oxygen Species and the Central Nervous System

1992 • 2,931 citations

Pericytes regulate the blood–brain barrier

2010 • 2,459 citations

Pericytes are required for blood–brain barrier integrity during embryogenesis

2010 • 1,848 citations

High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria

1997 • 1,695 citations

Production of Reactive Oxygen Species by Mitochondria

2003 • 1,519 citations

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

2010 • 1,284 citations

Generation of reactive oxygen species by the mitochondrial electron transport chain

2002 • 1,208 citations

Analysis of glutathione: implication in redox and detoxification

2003 • 1,126 citations

Pericyte physiology

1993 • 582 citations

Relation of Diabetes to Mild Cognitive Impairment

2007 • 569 citations

Proteins as biomarkers of oxidative/nitrosative stress in diseases: The contribution of redox proteomics

2004 • 439 citations

Activation of PKC-δ and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy

2009 • 402 citations

CNS Microvascular Pericytes Exhibit Multipotential Stem Cell Activity

2006 • 401 citations

Increased blood-brain barrier permeability in type II diabetes demonstrated by gadolinium magnetic resonance imaging

2002 • 398 citations

Neurodegenerative disorders associated with diabetes mellitus

2004 • 351 citations

Increased blood–brain barrier permeability and altered tight junctions in experimental diabetes in the rat: contribution of hyperglycaemia and matrix metalloproteinases

2006 • 312 citations

Lipid peroxide levels of serum lipoprotein fractions of diabetic patients

1981 • 305 citations

Role of the CNS microvascular pericyte in the blood-brain barrier

1998 • 301 citations

Pericyte Migration from the Vascular Wall in Response to Traumatic Brain Injury

2000 • 295 citations

Pericytes: Pluripotent Cells of the Blood Brain Barrier

2008 • 271 citations

Oxidative and nitrosative stress in brain mitochondria of diabetic rats

2005 • 261 citations

Pericyte Migration

2008 • 224 citations

Analysis of Glutathione, Glutathione Disulfide, Cysteine, Homocysteine, and Other Biological Thiols by High-Performance Liquid Chromatography Following Derivatization by N-(1-Pyrenyl)maleimide

1995 • 218 citations

Recent advances in pericyte biology--implications for health and disease.

1991 • 203 citations

Streptozotocin-induced diabetes progressively increases blood-brain barrier permeability in specific brain regions in rats

2006 • 192 citations

Type 2 diabetes and risk of cognitive impairment and dementia

2007 • 191 citations

The CNS microvascular pericyte: pericyte-astrocyte crosstalk in the regulation of tissue survival

2011 • 187 citations

Carbonic Anhydrase Inhibitors. The Mitochondrial Isozyme VB as a New Target for Sulfonamide and Sulfamate Inhibitors

2005 • 186 citations

Cognitive impairment and MRI correlates in the elderly patients with type 2 diabetes mellitus

2007 • 168 citations

Effects of hypoxia on endothelial/pericytic co-culture model of the blood–brain barrier

2004 • 153 citations

Pericyte Signaling in the Neurovascular Unit

2008 • 143 citations

Effect of Diabetes Mellitus on the Permeability of the Blood–Brain Barrier to Insulin

1997 • 142 citations

Cultured human and canine endothelial cells from brain microvessels

1988 • 110 citations

Capillary pericytes: Perspectives and future trends

1991 • 108 citations

Predictors of Cognitive Decline in Older Individuals With Diabetes

2008 • 108 citations

Cultured retinal capillary pericytes die by apoptosis after an abrupt fluctuation from high to low glucose levels: a comparative study with retinal capillary endothelial cells

1996 • 107 citations

Mitochondrial carbonic anhydrase CA VB: Differences in tissue distribution and pattern of evolution from those of CA VA suggest distinct physiological roles

2000 • 89 citations

Potential role of cerebral glutathione in the maintenance of blood-brain barrier integrity in rat.

1999 • 88 citations

Long-term effects of topiramate on bipolar mood instability, weight change and glycemic control: a case-series

2001 • 86 citations

The effect of exercise on brain antioxidant status of diabetic rats.

2002 • 85 citations

Differentiation‐dependent expression of CA V and the role of carbonic anhydrase isozymes in pyruvate carboxylation in adipocytes

1996 • 83 citations

Expression of Carbonic Anhydrase V in Pancreatic Beta Cells Suggests Role for Mitochondrial Carbonic Anhydrase in Insulin Secretion

1998 • 81 citations

Topiramate modulates pH of hippocampal CA3 neurons by combined effects on carbonic anhydrase and Cl⁻/HCO₃⁻ exchange

2004 • 78 citations

Microvascular Disease in Type 1 Diabetes Alters Brain Activation

2006 • 66 citations

Relationship of lipid peroxides to diabetic complications

1992 • 64 citations

Inhibition of CA V decreases glucose synthesis from pyruvate

1986 • 62 citations

Pericyte biology and diseases.

2005 • 61 citations

Carbonic anhydrase: inhibition results in decreased urea production by hepatocytes

1986 • 61 citations

Lipid peroxides and alpha-tocopherol in rat streptozotocin-induced diabetes mellitus.

1982 • 47 citations

Topiramate ameliorates hyperglycaemia and improves glucose‐stimulated insulin release in ZDF rats and db/db mice

2004 • 44 citations

Adjuvant Topiramate Administration: A Pharmacologic Strategy for Addressing NMDA Receptor Hypofunction in Schizophrenia

2003 • 37 citations

Myosin translocation in retinal pericytes during free-radical induced apoptosis

1999 • 34 citations

Mitochondrial carbonic anhydrase (isozyme V) in mouse and rat: cDNA cloning, expression, subcellular localization, processing, and tissue distribution.

1994 • 33 citations

Glucocorticoid-Induced Apoptosis in CNS Microvascular Pericytes

2003 • 28 citations

Glucose transporter GLUT1 in human brain microvessels revealed by ultrastructural immunocytochemistry.

1997 • 25 citations

Effect of Carbonic Anhydrase Inhibition and Acetoacetate on Anaplerotic Pyruvate Carboxylase Activity in Cultured Rat Astrocytes

1997 • 18 citations