Potential role of cerebral glutathione in the maintenance of blood-brain barrier integrity in rat.

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

1979 • 27,693 citations

A fluorometric method for determination of oxidized and reduced glutathione in tissues

1976 • 4,013 citations

Bromobenzene-Induced Liver Necrosis. Protective Role of Glutathione and Evidence for 3,4-Bromobenzene Oxide as the Hepatotoxic Metabolite

1974 • 3,074 citations

Glutathione metabolism and its selective modification.

1988 • 1,975 citations

BIOCHEMISTRY OF OXYGEN TOXICITY

1989 • 1,046 citations

Oxy-Radicals and Related Species: Their Formation, Lifetimes, and Reactions

1986 • 958 citations

Glutathione deficiency produced by inhibition of its synthesis, and its reversal; Applications in research and therapy

1991 • 906 citations

Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death

1997 • 719 citations

Development of the blood-brain barrier

1990 • 533 citations

THE INTERACTION OF SOLUBLE HORSERADISH PEROXIDASE WITH MOUSE PERITONEAL MACROPHAGES IN VITRO

1972 • 431 citations

Glutathione deficiency leads to mitochondrial damage in brain.

1991 • 428 citations

On the antioxidant effects of ascorbic acid and glutathione

1992 • 382 citations

Natural antioxidants. III. Antioxidative components isolated from rhizome of Curcuma longa L.

1985 • 311 citations

Implications of the Blood-Brain Barrier and Its Manipulation

1989 • 308 citations

Quantitative aspects of reversible osmotic opening of the blood-brain barrier

1980 • 276 citations

Gelatinase B modulates selective opening of the blood-brain barrier during inflammation

1998 • 233 citations

Low blood glutathione levels in healthy aging adults.

1992 • 206 citations

Inhibition of glutathione synthesis in the newborn rat: a model for endogenously produced oxidative stress.

1991 • 194 citations

Brain edema and cerebrovascular permeability during cerebral ischemia in rats.

1990 • 176 citations

Evidence for carrier-mediated transport of glutathione across the blood-brain barrier in the rat.

1990 • 163 citations

The role of methionine in glutathione biosynthesis by isolated hepatocytes

1977 • 159 citations

THE DEVELOPMENT OF THE BLOOD‐BRAIN BARRIER*

1957 • 150 citations

Turmerin: A water soluble antioxidant peptide from turmeric [Curcuma longa]

1992 • 125 citations

Enzymatic Protection Against Peroxidative Damage in Isolated Brain Capillaries

1987 • 86 citations

The Anatomic Basis of the Blood-Brain Barrier

1989 • 83 citations

Effect of diethylmaleate and other glutathione depletors on protein synthesis

1986 • 78 citations

Protective effects of tirilazad mesylate and metabolite U-89678 against blood-brain barrier damage after subarachnoid hemorrhage and lipid peroxidative neuronal injury

1996 • 76 citations

Evidence for the Existence of a Sodium-dependent Glutathione (GSH) Transporter

1996 • 76 citations

Pathophysiology of the blood-brain barrier

1996 • 75 citations

Free radical scavenger depletion in post-ischemic reperfusion brain damage

1993 • 70 citations

Lipid peroxidation, protein thiols and calcium homeostasis in bromobenzene-induced liver damage

1987 • 69 citations

Effect of oral glutathione on hepatic glutathione levels in rats and mice

1989 • 65 citations

21-aminosteroid and 2-(aminomethyl)chromans inhibition of arachidonic acid-induced lipid peroxidation and permeability enhancement in bovine brain microvessel endothelial cell monolayers

1995 • 50 citations

Methods for depleting brain glutathione

1989 • 41 citations

Morphine metabolism revisited. II. Isolation and chemical characterization of a glutathionylmorphine adduct from rat liver microsomal preparations

1984 • 41 citations

Effect of sulfhydryl group modification on the activities of 5-oxo-L-prolinase.

1982 • 36 citations

Effect of 2-cyclohexene-1-one-induced glutathione diminution on ischemia/reperfusion-induced alterations in the physical state of brain synaptosomal membrane proteins and lipids

1997 • 33 citations

Alterations in free radical scavenging mechanisms following blood-brain barrier disruption

1993 • 25 citations

Phenytoin metabolic activation: role of cytochrome P-450, glutathione, age, and sex in rats and mice.

1988 • 25 citations

Long-term home use of acetylcysteine in chronic bronchitis.

1975 • 9 citations

Role of lipid peroxidation on renal dysfunction associated with glutathione depletion. Effects of vitamin E

1991 • 8 citations

Influence of Pyrazolones on Hepatic Glutathione in Rats

1985 • 3 citations