Mechanism of modulation of dopamine .beta.-monooxygenase by pH and fumarate as deduced from initial rate and primary deuterium isotope effect studies

Enzyme structure and mechanism

1977 • 2,935 citations

[6] Statistical analysis of enzyme kinetic data

1979 • 2,002 citations

The Enzymatic Conversion of 3,4-Dihydroxyphenylethylamine to Norepinephrine

1960 • 435 citations

Determining the Chemical Mechanisms of Enzyme‐Catalyzed Reactions by Kinetic Studies

1977 • 340 citations

The Intrinsic Pk_A-Values of Functional Groups in Enzymes: Improper Deductions from the Ph-Dependence of Steady-State Parameter

1976 • 168 citations

Bioenergetic processes in chromaffin granules a new perspective on some old problems

1978 • 139 citations

Dopamine-β-hydroxylase

1973 • 120 citations

Kinetic studies of the enzymic dopamine β-hydroxylation reaction

1968 • 119 citations

Mechanism of dopamine-beta-hydroxylation. Semidehydroascorbate as the enzyme oxidation product of ascorbate.

1981 • 119 citations

pH Variation of isotope effects in enzyme-catalyzed reactions. 1. Isotope- and pH-dependent steps the same

1981 • 118 citations

pH Variation of isotope effects in enzyme-catalyzed reactions. 2. Isotope-dependent step not pH dependent. Kinetic mechanism of alcohol dehydrogenase

1981 • 100 citations

Direct spectrophotometric detection of ascorbate free radical formed by dopamine β-monooxygenase and by ascorbate oxidase

1980 • 92 citations

Effect of pH on the Process of Ternary‐Complex Interconversion in the liver‐Alcohol‐Dehydrogenase Reaction

1978 • 71 citations

Ascorbate as a natural constituent of chromaffin granules from the bovine adrenal medulla

1975 • 70 citations

Bovine adrenal medullary dopamine β-hydroxylase: Purification by affinity chromatography, kinetic studies and presence of essential histidyl residues

1973 • 67 citations

Minimal kinetic mechanism and general equation for deuterium isotope effects on enzymic reactions: uncertainty of detecting a rate-limiting step

1981 • 67 citations

Deduction of kinetic mechanism in multisubstrate enzyme reactions from tritium isotope effects. Application to dopamine beta-hydroxylase.

1980 • 58 citations

The Enzyme‐Bound Copper of Dopamine β‐Monooxygenase

1979 • 53 citations

Dopamine beta-hydroxylase. Comparative specificities and mechanisms of the oxygenation reactions.

1981 • 42 citations

Dopamine .beta.-hydroxylase: activity and inhibition in the presence of .beta.-substituted phenethylamines

1982 • 39 citations

Mechanism of tyrosine hydroxylase activation by phosphorylation

1982 • 25 citations

Effect of pH on bovine adrenal medulla dopamine‐β‐hydroxylase

1973 • 18 citations

[34] Deduction of kinetic mechanisms from primary Hydrogen isotope effects: Dopamine β-monooxygenase —A case history

1982 • 13 citations