Activation of heteromeric G protein-gated inward rectifier K ⁺ channels overexpressed by adenovirus gene transfer inhibits the excitability of hippocampal neurons

Ionic channels of excitable membranes

1985 • 7,199 citations

Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos.

1986 • 1,118 citations

The Ionic Channels in Excitable Membranes

1975 • 1,096 citations

A G Protein Couples Serotonin and GABA _B Receptors to the Same Channels in Hippocampus

1986 • 870 citations

Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification

1994 • 847 citations

The G-protein-gated atrial K+ channel IKAch is a heteromultimer of two inwardly rectifying K+-channel proteins

1995 • 830 citations

Über humorale übertragbarkeit der Herznervenwirkung

1921 • 817 citations

Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.

1987 • 766 citations

Liquid junction potentials and small cell effects in patch-clamp analysis

1991 • 681 citations

Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene.

1988 • 523 citations

Spermine and Spermidine as Gating Molecules for Inward Rectifier K ⁺ Channels

1994 • 520 citations

A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation

1995 • 510 citations

GABAB-receptor-activated K+ current in voltage-clamped CA3 pyramidal cells in hippocampal cultures.

1985 • 468 citations

Differential modulation of three separate K-conductances in hippocampal CA1 neurons by serotonin

1987 • 463 citations

IRK(1–3) and GIRK(1–4) Inwardly Rectifying K⁺Channel mRNAs Are Differentially Expressed in the Adult Rat Brain

1996 • 450 citations

The inward rectifier potassium channel family

1995 • 426 citations

Atrial G protein-activated K+ channel: expression cloning and molecular properties.

1993 • 355 citations

Strong voltage-dependent inward rectification of inward rectifier K+ channels is caused by intracellular spermine

1995 • 354 citations

Direct hyperpolarizing action of baclofen on hippocampal pyramidal cells

1984 • 342 citations

Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K ⁺ channel GIRK2

1997 • 336 citations

Drug receptors and the inhibition of nerve cells

1989 • 308 citations

Evidence that neuronal G-protein-gated inwardly rectifying K+ channels are activated by G beta gamma subunits and function as heteromultimers.

1995 • 304 citations

Enkephalin hyperpolarizes interneurones in the rat hippocampus.

1988 • 296 citations

Cloning provides evidence for a family of inward rectifier and G‐protein coupled K⁺ channels in the brain

1994 • 280 citations

Functional Effects of the Mouse weaver Mutation on G Protein–Gated Inwardly Rectifying K+ Channels

1996 • 269 citations

Dependence of an adenosine-activated potassium current on a GTP-binding protein in mammalian central neurons

1987 • 254 citations

Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolism.

1992 • 248 citations

Heteromultimerization of G-Protein-Gated Inwardly Rectifying K⁺Channel Proteins GIRK1 and GIRK2 and Their Altered Expression inweaverBrain

1996 • 244 citations

A-type potassium channels expressed from Shaker locus cDNA.

1988 • 225 citations

Characterization of GABAergic neurons in hippocampal cell cultures

1994 • 201 citations

Cloning and functional expression of a rat heart KATP channel

1994 • 184 citations

Cloning of a Xenopus laevis Inwardly Rectifying K+ Channel Subunit That Permits GIRK1 Expression of IKACh Currents in Oocytes

1996 • 176 citations

Analysis of adenosine actions on Ca2+ currents and synaptic transmission in cultured rat hippocampal pyramidal neurones.

1991 • 165 citations

Heterologous Multimeric Assembly Is Essential for K+ Channel Activity of Neuronal and Cardiac G-Protein-Activated Inward Rectifiers

1995 • 153 citations

Opioids activate both an inward rectifier and a novel voltage-gated potassium conductance in the hippocampal formation

1991 • 145 citations

G-protein-gated inward rectifier K+ channel proteins (GIRK1) are present in the soma and dendrites as well as in nerve terminals of specific neurons in the brain

1996 • 136 citations

Three serotonin responses in cultured mouse hippocampal and striatal neurons

1988 • 97 citations

GIRK1 immunoreactivity is present predominantly in dendrites, dendritic spines, and somata in the CA1 region of the hippocampus

1997 • 95 citations

A G-protein-activated inwardly rectifying K+ channel (GIRK4) from human hippocampus associates with other GIRK channels.

1996 • 93 citations

A G-protein-activated inwardly rectifying K+ channel (GIRK4) from human hippocampus associates with other GIRK channels

1996 • 88 citations

Adenovirus-mediated transfer of a gene encoding human apolipoprotein A-I into normal mice increases circulating high-density lipoprotein cholesterol.

1994 • 86 citations

Pancreatic Islet Cells Express a Family of Inwardly Rectifying K+ Channel Subunits Which Interact to Form G-protein-activated Channels

1995 • 78 citations

Polyamines in Human Brain: Regional Distribution and Influence of Aging

1995 • 62 citations

The measurement of ionic conductivities and mobilities of certain less common organic ions needed for junction potential corrections in electrophysiology

1995 • 59 citations

Heterologously expressed serotonin 1A receptors couple to muscarinic K+ channels in heart.

1991 • 59 citations

Colocalization of mu opioid receptors with GIRK1 potassium channels in the rat brain: an immunocytochemical study.

1995 • 47 citations

Electrophysiology of 5‐HT_1A receptors in the rat hippocampus and cortex

1992 • 36 citations

Functional Expression of an Epitope-tagged G protein-coupled K+ Channel (GIRK1)

1995 • 28 citations