Biochemical and Ultrastructural Processing of [125I]Epidermal Growth Factor in Rat Epidermis and Hair Follicles: Accumulation of Nuclear Label

Epidermal Growth Factor

1979 • 2,964 citations

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

1978 • 2,146 citations

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts.

1976 • 1,293 citations

Redistribution and Pinocytosis of Lymphocyte Surface Immunoglobulin Molecules Induced by Anti-Immunoglobulin Antibody

1971 • 1,093 citations

Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody.

1983 • 792 citations

Recycling receptors: The round-trip itinerary of migrant membrane proteins

1983 • 780 citations

Direct visualization of the binding and internalization of a ferritin conjugate of epidermal growth factor in human carcinoma cells A-431.

1979 • 528 citations

Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts.

1978 • 358 citations

Down regulation of epidermal growth factor receptors: direct demonstration of receptor degradation in human fibroblasts.

1984 • 357 citations

Comparison of Epidermal Growth Factor Binding and Receptor Distribution in Normal Human Epidermis and Epidermal Appendages

1984 • 316 citations

Down-regulation of the epidermal growth factor receptor in KB cells is due to receptor internalization and subsequent degradation in lysosomes.

1984 • 295 citations

EFFECTS OF THE EXTRACT OF THE MOUSE SUBMAXILLARY SALIVARY GLANDS ON THE SYMPATHETIC SYSTEM OF MAMMALS*

1960 • 271 citations

Molecular mechanism of mitogen action: Processing of receptor induced by epidermal growth factor

1978 • 271 citations

Interaction of platelet-derived growth factor with its fibroblast receptor. Demonstration of ligand degradation and receptor modulation.

1982 • 239 citations

Regulation of Cell Proliferation by Epidermal Growth Factor

1983 • 235 citations

Receptor-mediated endocytosis of epidermal growth factor by rat hepatocytes: receptor pathway.

1986 • 217 citations

Chromatin binding of epidermal growth factor, nerve growth factor, and platelet-derived growth factor in cells bearing the appropriate surface receptors.

1986 • 193 citations

Antibodies to High Molecular Weight Polypeptides of Desmosomes: Specific Localization of a Class of Junctional Proteins in Cells and Tissues

1981 • 181 citations

Co-localization of 125I-epidermal growth factor and ferritin-low density lipoprotein in coated pits: a quantitative electron microscopic study in normal and mutant human fibroblasts.

1982 • 171 citations

Monovalent ionophores inhibit secretion of procollagen and fibronectin from cultured human fibroblasts

1979 • 159 citations

Epidermal and Nerve Growth Factors in Mammalian Development

1981 • 154 citations

Relationship between epidermal growth factor receptor occupancy and mitogenic response. Quantitative analysis using a steady state model system.

1984 • 149 citations

Properties of the receptor for epidermal growth factor

1984 • 149 citations

Internalized insulin receptors are recycled to the cell surface in rat hepatocytes.

1982 • 142 citations

Insulin-induced down-regulation of insulin receptors in 3T3-L1 adipocytes. Altered rate of receptor inactivation.

1982 • 139 citations

Distribution and number of epidermal growth factor receptors in skin is related to epithelial cell growth

1983 • 124 citations

Distribution of Epidermal Growth Factor Receptors in Rat Tissues During Embryonic Skin Development, Hair Formation, and the Adult Hair Growth Cycle

1984 • 113 citations

Differences in Human Skin Between the Epidermal Growth Factor Receptor Distribution Detected by EGF Binding and Monoclonal Antibody Recognition

1985 • 113 citations

The morphologic pathway of binding and internalization of epidermal growth factor in cultured cells

1983 • 90 citations

Direct linkage of 125I-EGF to cell surface receptors. A useful artifact of chloramine-T treatment.

1982 • 89 citations

Epidermal Growth Factor Receptor in Human Epidermal Cells: Direct Demonstration in Cultured Cells

1982 • 84 citations

EFFECTS OF EPIDERMAL GROWTH FACTOR ON HAIR GROWTH IN THE MOUSE

1981 • 83 citations

Nuclear accumulation of epidermal growth factor in cultured bovine corneal endothelial and granulosa cells.

1981 • 81 citations

Isolation and characterization of a highly enriched preparation of receptosomes (endosomes) from a human cell line.

1983 • 73 citations

Epidermal growth factor delays the development of the epidermis and hair follicles of mice during growth of the first coat

1983 • 72 citations

Intracellular processing of epidermal growth factor and its effect on ligand-receptor interactions.

1985 • 71 citations

Role of the degradation process in the mitogenic effect of epidermal growth factor

1980 • 61 citations

Intracellular processing of epidermal growth factor. I. Acidification of 125I-epidermal growth factor in intracellular organelles.

1984 • 54 citations

Histomorphological effects of epidermal growth factor on skin and oral mucosa in neonatal mice

1980 • 45 citations

Modulation of the Epidermal Growth Factor Receptor of Human Keratinocytes by Calcium Ion

1983 • 41 citations

Restricted mobility of membrane constituents in cell-substrate focal contacts of chicken fibroblasts.

1982 • 37 citations

Accumulation of epidermal growth factor within cells does not depend on receptor recycling

1980 • 36 citations

Stages in specialization of fibroblast adhesion and deposition of extracellular matrix.

1983 • 30 citations

Monensin, like methylamine, prevents degradation of 125I-epidermal growth factor, causes intracellular accumulation of receptors and blocks the mitogenic response

1984 • 28 citations

Examination of various methods for the intensification of radioautographs by scintillators.

1979 • 8 citations