NR2B-Containing Receptors Mediate Cross Talk among Hippocampal Synapses

Glutamate uptake

2001 • 3,867 citations

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1999 • 2,319 citations

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

2002 • 1,612 citations

Molecular diversity of the NMDA receptor channel

1992 • 1,354 citations

Functional repression of cAMP response element in 6-hydroxydopamine-treated neuronal cells.

2006 • 1,287 citations

Quantitative Ultrastructural Analysis of Hippocampal Excitatory Synapses

1997 • 973 citations

Three-Dimensional Relationships between Hippocampal Synapses and Astrocytes

1999 • 844 citations

Homeostatic plasticity in neuronal networks: the more things change, the more they stay the same

1999 • 808 citations

Cell Type and Pathway Dependence of Synaptic AMPA Receptor Number and Variability in the Hippocampus

1998 • 798 citations

The Incorporation of NMDA Receptors with a Distinct Subunit Composition at Nascent Hippocampal SynapsesIn Vitro

1999 • 780 citations

Different modes of expression of AMPA and NMDA receptors in hippocampal synapses

1999 • 673 citations

The Number of Glutamate Transporter Subtype Molecules at Glutamatergic Synapses: Chemical and Stereological Quantification in Young Adult Rat Brain

1998 • 666 citations

Nonuniform Probability of Glutamate Release at a Hippocampal Synapse

1993 • 641 citations

Developmental switch in the expression of NMDA receptors occurs in vivo and in vitro

1993 • 447 citations

Extrasynaptic Glutamate Diffusion in the Hippocampus: Ultrastructural Constraints, Uptake, and Receptor Activation

1998 • 437 citations

The NMDA Receptor Is Coupled to the ERK Pathway by a Direct Interaction between NR2B and RasGRF1

2003 • 427 citations

Extrasynaptic Glutamate Spillover in the Hippocampus: Dependence on Temperature and the Role of Active Glutamate Uptake

1997 • 425 citations

NMDA channel behavior depends on agonist affinity

1992 • 401 citations

Postsynaptic contribution to long-term potentiation revealed by the analysis of miniature synaptic currents

1992 • 372 citations

Increased contribution of NR2A subunit to synaptic NMDA receptors in developing rat cortical neurons

1998 • 364 citations

Facilitation at single synapses probed with optical quantal analysis

2002 • 330 citations

NMDA Receptor Content of Synapses in Stratum Radiatum of the Hippocampal CA1 Area

2000 • 294 citations

Variation in the number, location and size of synaptic vesicles provides an anatomical basis for the nonuniform probability of release at hippocampal CA1 synapses

1995 • 290 citations

Glial Contribution to Glutamate Uptake at Schaffer Collateral–Commissural Synapses in the Hippocampus

1998 • 289 citations

Amplitude fluctuations of

1994 • 288 citations

Presynaptic Kainate Receptor Mediation of Frequency Facilitation at Hippocampal Mossy Fiber Synapses

2001 • 272 citations

Neuronal Glutamate Transporters Limit Activation of NMDA Receptors by Neurotransmitter Spillover on CA1 Pyramidal Cells

2001 • 256 citations

Cooperation between independent hippocampal synapses is controlled by glutamate uptake

2002 • 256 citations

Glutamate spillover suppresses inhibition by activating presynaptic mGluRs

2000 • 246 citations

Developmental Changes in NMDA Receptor Glycine Affinity and Ifenprodil Sensitivity Reveal Three Distinct Populations of NMDA Receptors in Individual Rat Cortical Neurons

1998 • 229 citations

Prolonged Synaptic Currents and Glutamate Spillover at the Parallel Fiber to Stellate Cell Synapse

2000 • 229 citations

Asymmetrical Allocation of NMDA Receptor ε2 Subunits in Hippocampal Circuitry

2003 • 211 citations

Neuronal Glutamate Uptake Contributes to GABA Synthesis and Inhibitory Synaptic Strength

2003 • 204 citations

Activity-Dependent Recruitment of Extrasynaptic NMDA Receptor Activation at an AMPA Receptor-Only Synapse

2002 • 201 citations

Activation of AMPA, Kainate, and Metabotropic Receptors at Hippocampal Mossy Fiber Synapses

1998 • 200 citations

Modulation of GABAergic Signaling among Interneurons by Metabotropic Glutamate Receptors

2000 • 189 citations

C-Terminal Truncation of NR2A Subunits Impairs Synaptic But Not Extrasynaptic Localization of NMDA Receptors

2000 • 184 citations

Glutamate and γ-aminobutyric acid mediate a heterosynaptic depression at mossy fiber synapses in the hippocampus

1999 • 182 citations

Barrel Cortex Critical Period Plasticity Is Independent of Changes in NMDA Receptor Subunit Composition

2001 • 182 citations

An Evaluation of Synapse Independence

2001 • 174 citations

A Monte Carlo Model Reveals Independent Signaling at Central Glutamatergic Synapses

2002 • 169 citations

High Probability Opening of NMDA Receptor Channels by L-Glutamate

1992 • 166 citations

Presynaptic Kainate Receptors that Enhance the Release of GABA on CA1 Hippocampal Interneurons

2001 • 161 citations

Kainate receptor-dependent axonal depolarization and action potential initiation in interneurons

2001 • 148 citations

Relationship between Availability of NMDA Receptor Subunits and Their Expression at the Synapse

2002 • 148 citations

Asymmetry of Glia near Central Synapses Favors Presynaptically Directed Glutamate Escape

2002 • 142 citations

Distinct synaptic and extrasynaptic NMDA receptors identified in dorsal horn neurones of the adult rat spinal cord

2000 • 137 citations

Development and Subunit Composition of Synaptic NMDA Receptors in the Amygdala: NR2B Synapses in the Adult Central Amygdala

2003 • 135 citations

Synaptic activation of AMPA receptors inhibits GABA release from cerebellar interneurons

2000 • 124 citations

Allosteric interaction between the amino terminal domain and the ligand binding domain of NR2A

2001 • 118 citations

Analysis of dendritic spines in rat CA1 pyramidal cells intracellularly filled with a fluorescent dye

1995 • 112 citations

The Role of Perisynaptic Glial Sheaths in Glutamate Spillover and Extracellular Ca2+ Depletion

2001 • 109 citations

Activation of NMDA Receptors in Rat Dentate Gyrus Granule Cells by Spontaneous and Evoked Transmitter Release

2003 • 97 citations

Synapses in hippocampus occupy only 1–2% of cell membranes and are spaced less than half-micron apart: a quantitative ultrastructural analysis with discussion of physiological implications

1998 • 82 citations

Enhancement of glutamate release uncovers spillover-mediated transmission by N-methyl-d-aspartate receptors in the rat hippocampus

1999 • 80 citations

Postsynaptic conversion of silent synapses during LTP affects synaptic gain and transmission dynamics

2001 • 73 citations

Extracellular Resistance in Cell Adhesion Measured with a Transistor Probe

2000 • 51 citations

Polyhedral Protein Cages Encase Synaptic Vesicles and Participate in Their Attachment to the Active Zone

1997 • 17 citations