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Abstract

References (40)

A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

1995 • 5,208 citations

Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures.

1995 • 1,968 citations

Annexin V-Affinity assay: A review on an apoptosis detection system based on phosphatidylserine exposure

1998 • 1,850 citations

High-Level Neuronal Expression of Aβ1–42in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation

2000 • 1,793 citations

Calpain and caspase: can you tell the difference?

2000 • 911 citations

The central executioners of apoptosis: caspases or mitochondria?

1998 • 772 citations

Programmed cell death and Bcl-2 protection in the absence of a nucleus.

1994 • 560 citations

Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury.

1998 • 514 citations

A Subfamily of P-Type ATPases with Aminophospholipid Transporting Activity

1996 • 472 citations

Apoptosis and the Nervous System

2000 • 469 citations

Molecular Cloning of Human Plasma Membrane Phospholipid Scramblase

1997 • 389 citations

Properties of the caspases

1998 • 370 citations

Synaptic and neuritic alterations during the progression of Alzheimer's disease

1994 • 355 citations

Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis.

1996 • 353 citations

Evidence for Synaptic Apoptosis

1998 • 342 citations

Rapid Preparation of Synaptosomes from Mammalian Brain Using Nontoxic Isoosmotic Gradient Material (Percoll)

1984 • 338 citations

Peptide inhibitors of the ice protease family arrest programmed cell death of motoneurons in vivo and in vitro

1995 • 324 citations

Calpain Functions in a Caspase-Independent Manner to Promote Apoptosis-Like Events During Platelet Activation

1999 • 318 citations

Amyloid β-peptide induces apoptosis-related events in synapses and dendrites

1998 • 254 citations

Sensitive method for measuring apoptosis and cell surface phenotype in human thymocytes by flow cytometry

1994 • 226 citations

The glutamatergic nerve terminal

1993 • 221 citations

Establishment of a Cell-Free System of Neuronal Apoptosis: Comparison of Premitochondrial, Mitochondrial, and Postmitochondrial Phases

1997 • 188 citations

Constitutive Death of Platelets Leading to Scavenger Receptor-mediated Phagocytosis

2000 • 171 citations

β-Amyloid Induces Local Neurite Degeneration in Cultured Hippocampal Neurons: Evidence for Neuritic Apoptosis

1998 • 162 citations

ALZHEIMER'S DISEASE AND RELATED DISORDERS

2001 • 158 citations

Phosphatidylserine Exposure during Apoptosis Is a Cell-Type-Specific Event and Does Not Correlate with Plasma Membrane Phospholipid Scramblase Expression

1999 • 151 citations

Involvement of multiple proteases during Fas‐mediated apoptosis in T lymphocytes

1995 • 136 citations

Phosphatidylserine Externalization Is a Downstream Event of Interleukin-1β–Converting Enzyme Family Protease Activation During Apoptosis

1997 • 127 citations

Effects of ICE-like protease and calpain inhibitors on neuronal apoptosis

1996 • 121 citations

Behavioral Effects of 5-HT2CReceptor Antagonism in the Substantia Nigra Zona Reticulata of the 6-Hydroxydopamine-Lesioned Rat Model of Parkinson's Disease

1998 • 80 citations

Temporal relationships between de novo protein synthesis, calpain and caspase 3-like protease activation, and DNA fragmentation during apoptosis in septo-hippocampal cultures

1998 • 78 citations

Binding of Annexin V to Membrane Products of Lipid Peroxidation

2001 • 69 citations

Quantitative characterization of crude synaptosomal fraction (P-2) components by flow cytometry

2000 • 59 citations

Lipid peroxidation associated protein damage in rat brain crude synaptosomal fraction mediated by iron and ascorbate

2001 • 56 citations

Choline Uptake and Acetylcholine Synthesis in Synaptosomes: Investigations Using Two Different Labeled Variants of Choline

1981 • 47 citations

SOME PROBLEMS INHERENT IN TRANSPORT STUDIES IN SYNAPTOSOMES

1978 • 46 citations

EFFECT OF PRETREATMENT UNDER VARIOUS CATIONIC CONDITIONS ON ACETYLCHOLINE CONTENT AND CHOLINE TRANSPORT IN RAT WHOLE BRAIN SYNAPTOSOMES

1978 • 42 citations

Synaptosomal transport and acetylation of choline

1977 • 41 citations

Differential subcellular localization of caspase family proteins in the adult rat brain

2001 • 33 citations

Caspase inhibition protects nerve terminals from in vitro degradation.

2002 • 14 citations

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