Complex Actions of 2-Aminoethyldiphenyl Borate on Store-operated Calcium Entry
Data up to Jan 2025
Total Citations Per Year
Abstract
References (38)
A model for receptor-regulated calcium entry
1986 • 2,535 citations
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function
2006 • 2,174 citations
Store-Operated Calcium Channels
2005 • 2,077 citations
STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx
2005 • 2,020 citations
STIM1, an essential and conserved component of store-operated Ca2+ channel function
2005 • 1,757 citations
Depletion of intracellular calcium stores activates a calcium current in mast cells
1992 • 1,748 citations
STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane
2005 • 1,358 citations
Orai1 is an essential pore subunit of the CRAC channel
2006 • 1,305 citations
CRACM1 Is a Plasma Membrane Protein Essential for Store-Operated Ca 2+ Entry
2006 • 1,285 citations
Capacitative calcium entry
1995 • 1,112 citations
Genome-wide RNAi screen of Ca 2+ influx identifies genes that regulate Ca 2+ release-activated Ca 2+ channel activity
2006 • 838 citations
The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER–plasma membrane junctions
2006 • 630 citations
Requirement of the Inositol Trisphosphate Receptor for Activation of Store-Operated Ca 2+ Channels
2000 • 582 citations
Amplification of CRAC current by STIM1 and CRACM1 (Orai1)
2006 • 576 citations
CRACM1 Multimers Form the Ion-Selective Pore of the CRAC Channel
2006 • 555 citations
Orai1 and STIM Reconstitute Store-operated Calcium Channel Function
2006 • 547 citations
Large Store-operated Calcium Selective Currents Due to Co-expression of Orai1 or Orai2 with the Intracellular Calcium Sensor, Stim1
2006 • 537 citations
Potentiation and inhibition of Ca2+ release‐activated Ca2+ channels by 2‐aminoethyldiphenyl borate (2‐APB) occurs independently of IP3 receptors
2001 • 492 citations
CRACM1, CRACM2, and CRACM3 Are Store-Operated Ca2+ Channels with Distinct Functional Properties
2007 • 369 citations
Coupling of STIM1 to store-operated Ca 2+ entry through its constitutive and inducible movement in the endoplasmic reticulum
2006 • 300 citations
Calcium Inhibition and Calcium Potentiation of Orai1, Orai2, and Orai3 Calcium Release-activated Calcium Channels
2007 • 236 citations
Aggregation of STIM1 underneath the plasma membrane induces clustering of Orai1
2006 • 225 citations
Role of the Phospholipase C-Inositol 1,4,5-Trisphosphate Pathway in Calcium Release-activated Calcium Current and Capacitative Calcium Entry
2001 • 221 citations
Emerging perspectives in store-operated Ca2+ entry: Roles of Orai, Stim and TRP
2006 • 215 citations
A non‐capacitative pathway activated by arachidonic acid is the major Ca2+ entry mechanism in rat A7r5 smooth muscle cells stimulated with low concentrations of vasopressin
1999 • 199 citations
2‐Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1‐dependent gating of CRAC channels
2008 • 190 citations
Store-dependent and -independent Modes Regulating Ca2+ Release-activated Ca2+ Channel Activity of Human Orai1 and Orai3
2008 • 183 citations
Modification of Store-operated Channel Coupling and Inositol Trisphosphate Receptor Function by 2-Aminoethoxydiphenyl Borate in DT40 Lymphocytes
2002 • 173 citations
Ca2+-store-dependent and -independent reversal of Stim1 localization and function
2008 • 172 citations
Assessment of the Role of the Inositol 1,4,5-Trisphosphate Receptor in the Activation of Transient Receptor Potential Channels and Store-operated Ca2+ Entry Channels
2001 • 171 citations
New molecular players in capacitative Ca2+ entry
2007 • 158 citations
An examination of the secretion‐like coupling model for the activation of the Ca2+ release‐activated Ca2+ current ICRAC in RBL‐1 cells
2001 • 143 citations
Capacitative calcium entry supports calcium oscillations in human embryonic kidney cells
2004 • 124 citations
Role of the microtubule cytoskeleton in the function of the store-operated Ca2+ channel activator STIM1
2007 • 124 citations
2-Aminoethoxydiphenyl borate (2-APB) inhibits capacitative calcium entry independently of the function of inositol 1,4,5-trisphosphate receptors.
2001 • 124 citations
Role of the store‐operated calcium entry proteins Stim1 and Orai1 in muscarinic cholinergic receptor‐stimulated calcium oscillations in human embryonic kidney cells
2007 • 104 citations
Stable Activation of Single Ca2+ Release-activated Ca2+ Channels in Divalent Cation-free Solutions
2001 • 103 citations
Dissociation of Regulated Trafficking of TRPC3 Channels to the Plasma Membrane from Their Activation by Phospholipase C
2006 • 66 citations