Fibroblast Growth Factors in Normal and Malignant Melanocytes^a

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

1991 • 2,230 citations

Molecular cloning and expression of human hepatocyte growth factor

1989 • 2,191 citations

THE HEPARIN-BINDING (FIBROBLAST) GROWTH FACTOR FAMILY OF PROTEINS

1989 • 1,948 citations

Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

1987 • 1,627 citations

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

1990 • 1,448 citations

The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus

1990 • 1,208 citations

Recent developments in the cell biology of basic fibroblast growth factor.

1989 • 1,049 citations

Nucleotide Sequence of a Bovine Clone Encoding the Angiogenic Protein, Basic Fibroblast Growth Factor

1986 • 1,032 citations

Human KGF is FGF-Related with Properties of a Paracrine Effector of Epithelial Cell Growth

1989 • 989 citations

Identification of a ligand for the c-kit proto-oncogene

1990 • 970 citations

Molecular cloning of a new transforming gene from a chemically transformed human cell line

1984 • 966 citations

Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms

1990 • 870 citations

Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium

1990 • 837 citations

Primary structure and functional expression of rat and human stem cell factor DNAs

1990 • 779 citations

The kit ligand: A cell surface molecule altered in steel mutant fibroblasts

1990 • 777 citations

Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.

1988 • 727 citations

Human Endothelial Cell Growth Factor: Cloning, Nucleotide Sequence, and Chromosome Localization

1986 • 679 citations

Purification and Complementary DNA Cloning of a Receptor for Basic Fibroblast Growth Factor

1989 • 660 citations

Autocrine activities of basic fibroblast growth factor: regulation of endothelial cell movement, plasminogen activator synthesis, and DNA synthesis.

1988 • 647 citations

Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors.

1990 • 635 citations

Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles

1990 • 632 citations

Selective proliferation of normal human melanocytes in vitro in the presence of phorbol ester and cholera toxin.

1982 • 552 citations

An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family

1987 • 525 citations

A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor.

1991 • 502 citations

Basic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes.

1988 • 489 citations

High Risk of Malignant Melanoma in Melanoma-Prone Families with Dysplastic Nevi

1985 • 458 citations

Expression cDNA Cloning of the KGF Receptor by Creation of a Transforming Autocrine Loop

1991 • 427 citations

The human FGF-5 oncogene encodes a novel protein related to fibroblast growth factors.

1988 • 425 citations

Isolation of an additional member of the fibroblast growth factor receptor family, FGFR-3.

1991 • 415 citations

Amino acid and cDNA sequences of a vascular endothelial cell mitogen that is homologous to platelet-derived growth factor.

1990 • 368 citations

The identification and partial characterization of the fibroblast growth factor receptor of baby hamster kidney cells.

1985 • 352 citations

Diverse forms of a receptor for acidic and basic fibroblast growth factors.

1990 • 352 citations

Deduced primary structure of rat hepatocyte growth factor and expression of the mRNA in rat tissues.

1990 • 333 citations

Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family.

1989 • 294 citations

cDNA sequence of human transforming gene hst and identification of the coding sequence required for transforming activity.

1987 • 293 citations

Regulation of tyrosinase in human melanocytes grown in culture.

1983 • 288 citations

Proliferation of human malignant melanomas is inhibited by antisense oligodeoxynucleotides targeted against basic fibroblast growth factor.

1989 • 270 citations

Purification and characterization of heparin-binding endothelial cell growth factors.

1986 • 263 citations

Acidic and basic fibroblast growth factors stimulate tyrosine kinase activity in vivo.

1988 • 261 citations

K-sam, an amplified gene in stomach cancer, is a member of the heparin-binding growth factor receptor genes.

1990 • 260 citations

bFGF is the putative natural growth factor for human melanocytes

1987 • 259 citations

Both normal and tumor cells produce basic fibroblast growth factor

1986 • 250 citations

bFGF as an autocrine growth factor for human melanomas.

1988 • 237 citations

Two forms of the basic fibroblast growth factor receptor-like mRNA are expressed in the developing mouse brain.

1990 • 228 citations

Cytogenetics of human malignant melanoma and premalignant lesions

1984 • 213 citations

Receptor for acidic fibroblast growth factor is related to the tyrosine kinase encoded by the fms-like gene (FLG).

1989 • 203 citations

A murine fibroblast growth factor (FGF) receptor expressed in CHO cells is activated by basic FGF and Kaposi FGF.

1990 • 196 citations

Cytogenetic Analysis of Melanocytes From Premalignant Nevi and Melanomas

1988 • 195 citations

Characterization and cDNA cloning of phospholipase C-gamma, a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.

1990 • 195 citations

Characterization of the receptor for keratinocyte growth factor. Evidence for multiple fibroblast growth factor receptors.

1990 • 187 citations

In situ detection of basic fibroblast growth factor by highly specific antibodies.

1990 • 168 citations

Identification of a developmentally regulated protein-tyrosine kinase by using anti-phosphotyrosine antibodies to screen a cDNA expression library.

1989 • 165 citations

Sequence analysis of mouse tyrosinase cDNA and the effect of melanotropin on its gene expression

1988 • 156 citations

Association of bovine brain-derived growth factor receptor with protein tyrosine kinase activity.

1986 • 151 citations

Transformation of murine melanocytes by basic fibroblast growth factor cDNA and oncogenes and selective suppression of the transformed phenotype in a reconstituted cutaneous environment.

1989 • 146 citations

Isolation of a rearranged human transforming gene following transfection of Kaposi sarcoma DNA.

1987 • 125 citations

Putative tyrosine kinases expressed in K-562 human leukemia cells.

1990 • 112 citations

Chromosomal localization of the hst oncogene and its co-amplification with the int.2 oncogene in a human melanoma.

1988 • 107 citations

The murine flg gene encodes a receptor for fibroblast growth factor.

1990 • 106 citations

Alternative splicing generates at least five different isoforms of the human basic-FGF receptor.

1991 • 104 citations

Growth Regulation of Human Melanocytes: Mitogenic Factors in Extracts of Melanoma, Astrocytoma, and Fibroblast Cell Lines

1985 • 95 citations

Basic FGF and TGF-β1 influence commitment to melanogenesis in neural crest-derived cells of avian embryos

1991 • 94 citations

Functional inhibition of endogenously produced urokinase decreases cell proliferation in a human melanoma cell line.

1989 • 91 citations

Private and public autocrine loops in neoplastic cells.

1989 • 90 citations

Localization of Basic Fibroblast Growth Factor mRNA in Melanocytic Lesions by In Situ Hybridization

1991 • 89 citations

Heparin-binding growth factor 1 stimulates tyrosine phosphorylation in NIH 3T3 cells.

1989 • 85 citations

The genes for basic and acidic fibroblast growth factors are on different human chromosomes

1986 • 78 citations

Purification of basic FGF receptors from rat brain

1988 • 63 citations

Growth regulation of cancer metastases by their host organ.

1988 • 51 citations

Responses of Cultured Melanocytes to Defined Growth Factors

1988 • 39 citations

Overexpression of Phospholipase C-γ in NIH 3T3 Fibroblasts Results in Increased Phosphatidylinositol Hydrolysis in Response to Platelet-Derived Growth Factor and Basic Fibroblast Growth Factor

1990 • 34 citations

Receptor functions and ligand-dependent transforming potential of a chimeric kit proto-oncogene.

1990 • 33 citations

Overexpression of phospholipase C-gamma in NIH 3T3 fibroblasts results in increased phosphatidylinositol hydrolysis in response to platelet-derived growth factor and basic fibroblast growth factor.

1990 • 21 citations

Growth stimulation of human melanocytes: Identification and characterization of melanoma-derived melanocyte growth factor (M-McGF)

1987 • 20 citations

The human basic fibroblast growth factor gene is located on the long arm of chromosome 4 at bands q26-q27.

1990 • 18 citations

Growth Regulation in Normal and Malignant Melanocytes

1990 • 7 citations