Biosynthesis and intracellular transport of a bile canalicular plasma membrane protein: Studiesin vivo and in the perfused rat liver

Phase separation of integral membrane proteins in Triton X-114 solution.

1981 • 3,366 citations

Morphogenesis of the Polarized Epithelial Cell Phenotype

1989 • 1,087 citations

Cell Surface Polarity in Epithelia

1985 • 880 citations

Structural and functional polarity of canalicular and basolateral plasma membrane vesicles isolated in high yield from rat liver.

1984 • 393 citations

Biogenesis of the rat hepatocyte plasma membrane in vivo: comparison of the pathways taken by apical and basolateral proteins using subcellular fractionation.

1987 • 383 citations

Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus.

1990 • 369 citations

Isolation of rat hepatocyte plasma membranes. I. Presence of the three major domains.

1983 • 306 citations

Plasma membrane protein sorting in polarized epithelial cells.

1992 • 272 citations

Phosphorylation of the Polymeric Immunoglobulin Receptor Required for Its Efficient Transcytosis

1990 • 267 citations

Endocytosis in filter-grown Madin-Darby canine kidney cells.

1989 • 264 citations

Sorting of endogenous plasma membrane proteins occurs from two sites in cultured human intestinal epithelial cells (Caco-2)

1990 • 262 citations

Ligands internalized through coated or noncoated invaginations follow a common intracellular pathway.

1987 • 254 citations

Biliary transport of IgA: role of secretory component.

1979 • 233 citations

Biogenetic pathways of plasma membrane proteins in Caco-2, a human intestinal epithelial cell line.

1990 • 228 citations

Quantitative relationship between autophagy and proteolysis during graded amino acid deprivation in perfused rat liver.

1981 • 223 citations

Endocytosis and signals for internalization

1991 • 209 citations

Coated pits act as molecular filters.

1980 • 208 citations

Rat bile as a convenient source of secretory IgA and free secretory component

1977 • 170 citations

Identification of rat hepatocyte plasma membrane proteins using monoclonal antibodies.

1985 • 140 citations

Transcellular transport of polymeric IgA in the rat hepatocyte: biochemical and morphological characterization of the transport pathway.

1985 • 134 citations

Biochemical characterization of domain-specific glycoproteins of the rat hepatocyte plasma membrane.

1985 • 134 citations

High levels of secretory IgA and free secretory component in the serum of rats with bile duct obstruction.

1978 • 128 citations

5'nucleotidase is sorted to the apical domain of hepatocytes via an indirect route [published erratum appears in J Cell Biol 1993 Nov;123(3):following 767]

1992 • 121 citations

Plasma membrane protein sorting in epithelial cells: Do secretory pathways hold the key?

1988 • 121 citations

Galactose transfer to endogenous acceptors within Golgi fractions of rat liver.

1982 • 105 citations

Amino acid and hormonal control of macromolecular turnover in perfused rat liver. Evidence for selective autophagy.

1987 • 99 citations

Endocytosis

1989 • 97 citations

The preendosomal compartment comprises distinct coated and noncoated endocytic vesicle populations.

1991 • 97 citations

Endogenous and exogenous domain markers of the rat hepatocyte plasma membrane.

1985 • 92 citations

Protein traffic between distinct plasma membrane domains: Isolation and characterization of vesicular carriers involved in transcytosis

1991 • 89 citations

Human interleukin 1 beta is not secreted from hamster fibroblasts when expressed constitutively from a transfected cDNA.

1988 • 87 citations

Formation of plasma membrane domains in rat hepatocytes and hepatoma cell lines in culture

1988 • 84 citations

Fluid phase endocytosis by cultured rat hepatocytes and perfused rat liver: implications for plasma membrane turnover and vesicular trafficking of fluid phase markers.

1986 • 80 citations

Hepatocyte Handling of Immunoglobulin a in the Rat: The Role of Microtubules

1983 • 79 citations

Newly synthesized hepatocyte plasma membrane proteins are transported in transcytotic vesicles in the bile duct-ligated rat

1993 • 75 citations

Control of protein traffic between distinct plasma membrane domains. Requirement for a novel 108,000 protein in the fusion of transcytotic vesicles with the apical plasma membrane.

1993 • 71 citations

Biogenesis of the polymeric IgA receptor in rat hepatocytes. II. Localization of its intracellular forms by cell fractionation studies.

1985 • 68 citations

Extrahepatic obstructive cholestasis reverses the bile salt secretory polarity of rat hepatocytes.

1989 • 59 citations

Distribution of secretory component in hepatocytes and its mode of transfer into bile

1980 • 55 citations

Cell Surface Glycoproteins of Hepatocytes and Hepatoma Cells Identified by Monoclonal Antibodies

1986 • 51 citations

Effect of colchicine on the transfer of IgA across hepatocytes into bile in isolated perfused rat livers

1980 • 50 citations

Altered Zonal Expression of the Cd26 Antigen (Dipeptidyl Peptidase Iv) in Human Cirrhotic Liver

1992 • 49 citations

Transcytotic vesicular carriers for polymeric iga receptors accumulate in rat hepatocytes after bile duct ligation

1991 • 47 citations

Dynamics of four rat liver plasma membrane proteins and polymeric IgA receptor. Rates of synthesis and selective loss into the bile.

1992 • 45 citations

Characterization of rat hepatocyte plasma membrane domains by monoclonal antibodies.

1985 • 41 citations

Changes in IgA Following Varying Degrees of Biliary Obstruction in the Rat

1983 • 39 citations

Effect of colchicine and phalloidin on the distribution of three plasma membrane antigens in rat hepatocytes: Comparison with bile duct ligation

1987 • 36 citations

Sorting of plasma membrane proteins in epithelial cells

1991 • 32 citations

[47] Biogenesis of the rat hepatocyte plasma membrane

1990 • 30 citations

Uneven distribution of enzymatic alterations on the liver cell surface in experimental extrahepatic cholestasis of rat

1978 • 29 citations

Marker enzymes in rat liver vesicles involved in transcellular transport

1989 • 25 citations

Distribution and processing of the polymeric immunoglobulin receptor in the rat hepatocyte: morphological and biochemical characterization of subcellular fractions.

1986 • 18 citations

Analysis of hepatocyte plasma membrane domains during rat development using monoclonal antibodies.

1988 • 16 citations

Hepatic accumulation of lysosomes and defective transcytotic vesicular pathways in cirrhotic rat liver

1992 • 16 citations

Analysis of hepatocyte plasma membrane polarity during rat azo dye hepatocarcinogenesis using monoclonal antibodies directed against domain-associated antigens.

1988 • 11 citations

Plasma Membrane Biogenesis and Vesicle Traffic in Polarized Hepatocytes: What can Perturbations Tell Us?

1992 • 2 citations